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The map label for this gene is fur [H]

Identifier: 209547633

GI number: 209547633

Start: 20166

End: 20594

Strand: Reverse

Name: fur [H]

Synonym: Rleg2_0021

Alternate gene names: 209547633

Gene position: 20594-20166 (Counterclockwise)

Preceding gene: 209547634

Following gene: 209547632

Centisome position: 0.45

GC content: 62.0

Gene sequence:

>429_bases
ATGCCTGATGTAGCCAAGACCCTTGAGGAGCTTTGCACCGAACGCGGCATGCGCATGACCGAGCAGCGCCGCGTCATCGC
GCGCATCCTCGAAGATTCGGAAGACCATCCCGATGTCGAAGAGCTCTACCGCCGCTCGGTGAAGGTCGATGCGAAGATCT
CGATCTCGACCGTCTACCGCACGGTGAAACTGTTCGAGGATGCCGGCATCATCGCCCGCCACGATTTCCGCGACGGGCGC
TCGCGCTATGAAACGGTGCCGGAAGAGCATCACGACCACCTGATCGACCTGAAGACCGGCACGGTCATCGAATTCCGCTC
GCCGGAGATCGAGGCGCTGCAGGAGCGCATCGCCCGCGAGCACGGCTTCAAGCTGGTCGACCACCGGCTGGAACTCTACG
GCGTTCCGCTGAAGAAGGAAGACCTCTGA

Upstream 100 bases:

>100_bases
AGCGCGTTCTTCGCTAGTTCCCTGACAGAGAGATGACATGCTGGCGGGCGCAAACGCCGTCCGGCATTGTCGCAGGACGA
ATATCTTTTGAAGGCGGGCC

Downstream 100 bases:

>100_bases
AGCAATGGCCGCCGGGGAGACCAGCCTTTGATCGCCTGGCTGCGCATTGCCTGTGCTGCGGTCGTCATCCTGATCGTCAG
CATCGTGCTCGTGCCGCTGC

Product: Fur family ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MPDVAKTLEELCTERGMRMTEQRRVIARILEDSEDHPDVEELYRRSVKVDAKISISTVYRTVKLFEDAGIIARHDFRDGR
SRYETVPEEHHDHLIDLKTGTVIEFRSPEIEALQERIAREHGFKLVDHRLELYGVPLKKEDL

Sequences:

>Translated_142_residues
MPDVAKTLEELCTERGMRMTEQRRVIARILEDSEDHPDVEELYRRSVKVDAKISISTVYRTVKLFEDAGIIARHDFRDGR
SRYETVPEEHHDHLIDLKTGTVIEFRSPEIEALQERIAREHGFKLVDHRLELYGVPLKKEDL
>Mature_141_residues
PDVAKTLEELCTERGMRMTEQRRVIARILEDSEDHPDVEELYRRSVKVDAKISISTVYRTVKLFEDAGIIARHDFRDGRS
RYETVPEEHHDHLIDLKTGTVIEFRSPEIEALQERIAREHGFKLVDHRLELYGVPLKKEDL

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=120, Percent_Identity=43.3333333333333, Blast_Score=107, Evalue=3e-25,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16681; Mature: 16550

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDVAKTLEELCTERGMRMTEQRRVIARILEDSEDHPDVEELYRRSVKVDAKISISTVYR
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEHHHHHHH
TVKLFEDAGIIARHDFRDGRSRYETVPEEHHDHLIDLKTGTVIEFRSPEIEALQERIARE
HHHHHHCCCCEEECCCCCHHHHHHCCCCHHCCCEEECCCCCEEEECCCCHHHHHHHHHHH
HGFKLVDHRLELYGVPLKKEDL
HCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PDVAKTLEELCTERGMRMTEQRRVIARILEDSEDHPDVEELYRRSVKVDAKISISTVYR
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEHHHHHHH
TVKLFEDAGIIARHDFRDGRSRYETVPEEHHDHLIDLKTGTVIEFRSPEIEALQERIARE
HHHHHHCCCCEEECCCCCHHHHHHCCCCHHCCCEEECCCCCEEEECCCCHHHHHHHHHHH
HGFKLVDHRLELYGVPLKKEDL
HCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9835040 [H]