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The map label for this gene is hrcA [H]

Identifier: 209547619

GI number: 209547619

Start: 6610

End: 7698

Strand: Direct

Name: hrcA [H]

Synonym: Rleg2_0007

Alternate gene names: 209547619

Gene position: 6610-7698 (Clockwise)

Preceding gene: 209547614

Following gene: 209547620

Centisome position: 0.15

GC content: 63.73

Gene sequence:

>1089_bases
ATGGGCATCAGGTCGACATCGGTTTCGGATGCCGTTGCTGCGCTGGACGAGCGCTCCAGGGAAATTTTTCGCCGCATCGT
CGAAGGCTATCTGGAGAGCGGCGAGCCGCTCGGTTCGCGCAATCTGTCCCGCCTGCTGCCGATGTCGCTGTCGCCGGCCT
CGGTGCGCAACGTCATGAGCGATCTCGAAGATCTCGGCCTCATCTATTCGCCGCATATCAGCGCCGGCCGGCTGCCGACC
CAGATCGGCCTGCGTTTCTTCGTCGATGCCTTCATGCAGGTCGGTGATCTCTCCGCCGAGGACCGCGCCAGCATCGACCG
CCAGGTGCGGGCCGAGAGCGGTGGCAACCCGGTGGAATCGATGATGAATGAGGCAAGCCGCATGCTGTCCGGCATTTCGC
GCGGCGCCGGCCTGGTCATCACCTCGAAAAGCGATCCGGTGCTCAAACATGTCGAGTTCATCCGGCTGGAGCCGACAAAG
GCGCTGGCTGTGCTCGTCGGCGATCACGATCAGGTGGAAAACCGCATCATCGAACTGCCGGCGGGCGTCACCTCCTCGCA
GCTGGCGGAGGCGGCGAATTTTCTCAACGCCCATATGTCCGGCCAGACCCTGCCGGAGCTGCGCAAACAATTAAGCCAGC
TGAAGGATAACGTCCGTCACGAACTCGACGCCCTGTCGCGTGATCTCGTCGAGCGCGGCATCGCCGTCTGGGCCGGCAGC
CCGGACGAGGGAAAGCCGGCGCAGCTGATCATCCGCGGCCGCGCCAACCTACTTGAAGGTCTCGCCGGCGCCGAGGATCT
CGACCGGCTGCGGCTGCTGTTCGACGATCTCGAAAAGAAGGACAGCCTGATCGAGATCCTCAATCTCGCCGAAACCGGCT
CGGGCGTGCGCATCTTCATCGGCTCGGAAAACAAGCTCTTCTCGCTGTCCGGCTCATCGCTCATCGTCGCGCCCTATCGG
GACGACGACGATCGCATCGTCGGCGCCGTCGGCGTCATCGGCCCGACGCGGCTCAATTATTCCCGCATCGTGCCGATGGT
GGACTACACCGCCCAGCTCGTCTCCCGGCTTTCGCGCAATCCGCTTTGA

Upstream 100 bases:

>100_bases
TTCTACGATTGGCGGCGCCTATTTGCAAATTCCCTTTTGCCACGGCTGCGAGTTTGACTTACTTTTCGCGAAGTATCATC
AGCGCGGGTTCGGGAGTTTC

Downstream 100 bases:

>100_bases
CCAGTTTGACGAAGACCGCGGAATTTTCGCTTCTTTGTCACGCAGACTTGATTTTTTTCGGTCAAACCTCGATATCGGGC
GCATCTGAAGACACCAACCG

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MGIRSTSVSDAVAALDERSREIFRRIVEGYLESGEPLGSRNLSRLLPMSLSPASVRNVMSDLEDLGLIYSPHISAGRLPT
QIGLRFFVDAFMQVGDLSAEDRASIDRQVRAESGGNPVESMMNEASRMLSGISRGAGLVITSKSDPVLKHVEFIRLEPTK
ALAVLVGDHDQVENRIIELPAGVTSSQLAEAANFLNAHMSGQTLPELRKQLSQLKDNVRHELDALSRDLVERGIAVWAGS
PDEGKPAQLIIRGRANLLEGLAGAEDLDRLRLLFDDLEKKDSLIEILNLAETGSGVRIFIGSENKLFSLSGSSLIVAPYR
DDDDRIVGAVGVIGPTRLNYSRIVPMVDYTAQLVSRLSRNPL

Sequences:

>Translated_362_residues
MGIRSTSVSDAVAALDERSREIFRRIVEGYLESGEPLGSRNLSRLLPMSLSPASVRNVMSDLEDLGLIYSPHISAGRLPT
QIGLRFFVDAFMQVGDLSAEDRASIDRQVRAESGGNPVESMMNEASRMLSGISRGAGLVITSKSDPVLKHVEFIRLEPTK
ALAVLVGDHDQVENRIIELPAGVTSSQLAEAANFLNAHMSGQTLPELRKQLSQLKDNVRHELDALSRDLVERGIAVWAGS
PDEGKPAQLIIRGRANLLEGLAGAEDLDRLRLLFDDLEKKDSLIEILNLAETGSGVRIFIGSENKLFSLSGSSLIVAPYR
DDDDRIVGAVGVIGPTRLNYSRIVPMVDYTAQLVSRLSRNPL
>Mature_361_residues
GIRSTSVSDAVAALDERSREIFRRIVEGYLESGEPLGSRNLSRLLPMSLSPASVRNVMSDLEDLGLIYSPHISAGRLPTQ
IGLRFFVDAFMQVGDLSAEDRASIDRQVRAESGGNPVESMMNEASRMLSGISRGAGLVITSKSDPVLKHVEFIRLEPTKA
LAVLVGDHDQVENRIIELPAGVTSSQLAEAANFLNAHMSGQTLPELRKQLSQLKDNVRHELDALSRDLVERGIAVWAGSP
DEGKPAQLIIRGRANLLEGLAGAEDLDRLRLLFDDLEKKDSLIEILNLAETGSGVRIFIGSENKLFSLSGSSLIVAPYRD
DDDRIVGAVGVIGPTRLNYSRIVPMVDYTAQLVSRLSRNPL

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 39433; Mature: 39301

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIRSTSVSDAVAALDERSREIFRRIVEGYLESGEPLGSRNLSRLLPMSLSPASVRNVMS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHH
DLEDLGLIYSPHISAGRLPTQIGLRFFVDAFMQVGDLSAEDRASIDRQVRAESGGNPVES
HHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHH
MMNEASRMLSGISRGAGLVITSKSDPVLKHVEFIRLEPTKALAVLVGDHDQVENRIIELP
HHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHEECCCCEEEEEECCHHHHHHHHEECC
AGVTSSQLAEAANFLNAHMSGQTLPELRKQLSQLKDNVRHELDALSRDLVERGIAVWAGS
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
PDEGKPAQLIIRGRANLLEGLAGAEDLDRLRLLFDDLEKKDSLIEILNLAETGSGVRIFI
CCCCCCCEEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
GSENKLFSLSGSSLIVAPYRDDDDRIVGAVGVIGPTRLNYSRIVPMVDYTAQLVSRLSRN
CCCCCEEEECCCEEEEEECCCCCCCEEEEEECCCCCCCCHHHHCHHHHHHHHHHHHHHCC
PL
CC
>Mature Secondary Structure 
GIRSTSVSDAVAALDERSREIFRRIVEGYLESGEPLGSRNLSRLLPMSLSPASVRNVMS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHH
DLEDLGLIYSPHISAGRLPTQIGLRFFVDAFMQVGDLSAEDRASIDRQVRAESGGNPVES
HHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHH
MMNEASRMLSGISRGAGLVITSKSDPVLKHVEFIRLEPTKALAVLVGDHDQVENRIIELP
HHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHEECCCCEEEEEECCHHHHHHHHEECC
AGVTSSQLAEAANFLNAHMSGQTLPELRKQLSQLKDNVRHELDALSRDLVERGIAVWAGS
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECC
PDEGKPAQLIIRGRANLLEGLAGAEDLDRLRLLFDDLEKKDSLIEILNLAETGSGVRIFI
CCCCCCCEEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
GSENKLFSLSGSSLIVAPYRDDDDRIVGAVGVIGPTRLNYSRIVPMVDYTAQLVSRLSRN
CCCCCEEEECCCEEEEEECCCCCCCEEEEEECCCCCCCCHHHHCHHHHHHHHHHHHHHCC
PL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA