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The map label for this gene is cscK [H]

Identifier: 209400885

GI number: 209400885

Start: 3307410

End: 3308324

Strand: Reverse

Name: cscK [H]

Synonym: ECH74115_3592

Alternate gene names: 209400885

Gene position: 3308324-3307410 (Counterclockwise)

Preceding gene: 209397537

Following gene: 209399468

Centisome position: 59.37

GC content: 52.24

Gene sequence:

>915_bases
ATGTCAGCCAAAGTATGGGTTTTAGGGGATGCGGTCGTAGATCTCTTGCCAGAATCAGACGGGCGGCTACTGCCTTGTCC
TGGCGGCGCGCCAGCTAACGTTGCGGTGGGAATCGCCAGATTAGGCGGAACAAGTGGGTTTATAGGTCGGGTGGGGGATG
ATCCTTTTGGTGCATTAATGCAAAGAACGCTGCTAACTGAGGGAGTCGATATCACGTATCTGAAGCAAGATGAATGGCAC
CGGACATCCACGGTGCTTGTCGATCTGAACGATCAAGGGGAACGTTCATTTACGTTTATGGTCCGCCCCAGTGCCGATCT
TTTTTTAGAGACGACAGACTTGCCCTGCTGGCGACATGGCGAATGGTTACATCTCTGTTCAATTGCGTTGTCTGCCGAGC
CTTCGCGTACCAGCGCATTTACTGCGATGACGGAGATCCGGCATGCCGGAGGTTTTGTCAGCTTCGATCCCAATATTCGT
GAAGATCTATGGCAAGACGAGCATTTGCTCCGCTTGTGTTTGCGGCAGGCGCTACAACTGGCGGATGTCGTCAAGCTCTC
GGAAGAAGAATGGCGACTTATCAGTGGAAAAACACAGAACGATCGGGATATATGCGCCCTGGCAAAAGAGTATGAGATCG
CCATGCTGTTGGTGACTAAAGGTGCAGAAGGGGTGGTGGTCTGTTATCGAGGACAAGTTCACCATTTTGCTGGAATGTCT
GTGGATTGTGTCGATAGCACGGGGGCGGGAGATGCGTTCGTTGCCGGGTTACTCACAGGTCTGTCCTCTACGGGATTATC
TACAGATGAGAGAGAAATGCGACGAATTATCGATCTCGCTCAACGTTGCGGAGCGCTTGCAGTAACGGCGAAAGGGGCAA
TGACAGCGCTGCCATGTCGACAAGAACTGGAATAG

Upstream 100 bases:

>100_bases
CATTTTGTGATCGAATATGCATGTTTTAGTAAATCCATGACGATTTTGCGAAAAAGAGGTTTATCACTATGCGTAAGTCA
GATGAATTTAAGGGAAAAAA

Downstream 100 bases:

>100_bases
TGAGAAGTAAACGGCGAAGTCGCTCTTATCTCTAAATAGGACGTGAATTTTTTAACGACAGGCAGGTAATTATGGCACTG
AATATTCCATTCAGAAATGC

Product: aminoimidazole riboside kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MSAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGTSGFIGRVGDDPFGALMQRTLLTEGVDITYLKQDEWH
RTSTVLVDLNDQGERSFTFMVRPSADLFLETTDLPCWRHGEWLHLCSIALSAEPSRTSAFTAMTEIRHAGGFVSFDPNIR
EDLWQDEHLLRLCLRQALQLADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAGMS
VDCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRIIDLAQRCGALAVTAKGAMTALPCRQELE

Sequences:

>Translated_304_residues
MSAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGTSGFIGRVGDDPFGALMQRTLLTEGVDITYLKQDEWH
RTSTVLVDLNDQGERSFTFMVRPSADLFLETTDLPCWRHGEWLHLCSIALSAEPSRTSAFTAMTEIRHAGGFVSFDPNIR
EDLWQDEHLLRLCLRQALQLADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAGMS
VDCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRIIDLAQRCGALAVTAKGAMTALPCRQELE
>Mature_303_residues
SAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGTSGFIGRVGDDPFGALMQRTLLTEGVDITYLKQDEWHR
TSTVLVDLNDQGERSFTFMVRPSADLFLETTDLPCWRHGEWLHLCSIALSAEPSRTSAFTAMTEIRHAGGFVSFDPNIRE
DLWQDEHLLRLCLRQALQLADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAGMSV
DCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRIIDLAQRCGALAVTAKGAMTALPCRQELE

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=294, Percent_Identity=26.8707482993197, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790193, Length=282, Percent_Identity=28.0141843971631, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082281, Length=273, Percent_Identity=26.007326007326, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082343, Length=303, Percent_Identity=27.3927392739274, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=284, Percent_Identity=28.169014084507, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.4 [H]

Molecular weight: Translated: 33108; Mature: 32977

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGTSGFIGRVGDDPFGALM
CCCEEEEECHHHHHHCCCCCCCEEECCCCCCCHHEEEEEHHCCCCCCCCCCCCCHHHHHH
QRTLLTEGVDITYLKQDEWHRTSTVLVDLNDQGERSFTFMVRPSADLFLETTDLPCWRHG
HHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCEEEEEECCCCCEEEEECCCCCCCCC
EWLHLCSIALSAEPSRTSAFTAMTEIRHAGGFVSFDPNIREDLWQDEHLLRLCLRQALQL
CEEEEEEEHCCCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHHCCCHHHHHHHHHHHHHH
ADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAGMS
HHHHHCCCCCEEEECCCCCCCCHHHHHHHCCEEEEEEEECCCCEEEEEEECCEEECCCCE
VDCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRIIDLAQRCGALAVTAKGAMTALPCR
EEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCEEECCCH
QELE
HHCC
>Mature Secondary Structure 
SAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGTSGFIGRVGDDPFGALM
CCEEEEECHHHHHHCCCCCCCEEECCCCCCCHHEEEEEHHCCCCCCCCCCCCCHHHHHH
QRTLLTEGVDITYLKQDEWHRTSTVLVDLNDQGERSFTFMVRPSADLFLETTDLPCWRHG
HHHHHHCCCCEEEECCCCCCCEEEEEEEECCCCCCEEEEEECCCCCEEEEECCCCCCCCC
EWLHLCSIALSAEPSRTSAFTAMTEIRHAGGFVSFDPNIREDLWQDEHLLRLCLRQALQL
CEEEEEEEHCCCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHHCCCHHHHHHHHHHHHHH
ADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAGMS
HHHHHCCCCCEEEECCCCCCCCHHHHHHHCCEEEEEEEECCCCEEEEEEECCEEECCCCE
VDCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRIIDLAQRCGALAVTAKGAMTALPCR
EEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCEEECCCH
QELE
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA