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The map label for this gene is yfcH [H]

Identifier: 209400621

GI number: 209400621

Start: 3189240

End: 3190133

Strand: Direct

Name: yfcH [H]

Synonym: ECH74115_3444

Alternate gene names: 209400621

Gene position: 3189240-3190133 (Clockwise)

Preceding gene: 209399151

Following gene: 209395720

Centisome position: 57.24

GC content: 54.81

Gene sequence:

>894_bases
ATGAACATAGTGATCACCGGAGGGACGGGATTAATTGGTCGCCATTTGATTCCACGTTTGCTGGAGCTGGGCCATCAAAT
CACGGTAATGACGCGTAACCCGCAGAAAGCCAGTTCCGTTCTCGGCCCTCGGGTGACACTATGGCAAGGGCTTGCCGATC
AAAGCAACCTCAACGGCATTGATGCGGTAATCAACCTGGCCGGAGAACCGATTGCTGATAAACGTTGGACTCACGAGCAA
AAAGAGCGTCTCTGCCAAAGCCGCTGGAATATCACGCAAAAACTGGTCGATTTGATTAATGCCAGCGACACGCCACCGTC
GGTACTCATTTCCGGCTCGGCAACGGGCTATTATGGCGACTTAGGTGAAGTGGTGGTTACCGAAGAGGAACCGCCGCATA
ACAAATTTACCCATAAACTCTGCGCCCGCTGGGAAGAAATTGCCTGTCGGGCGCAAAGTGACAAAACGCGAGTGTGCCTG
CTGCGTACCGGCGTAGTGCTGGCACCGGATGGCGGTATTCTCGGTAAAATGCTGCCGCCGTTTCGTCTTGGCCTGGGCGG
GCCGATTGGTTCCGGTCGGCAGTATCTGGCCTGGATTCATATCGATGATATGGTCAACGGCATTCTCTGGCTGCTGGATA
ACGAGCTGCGCGGGCCATTTAATATGGTTTCGCCCTACCCGATACGCAATGAACAATTTGCCCATGCGCTCGGTCATGCG
CTGCATCGCCCGGCTATTTTGCGCGTCCCCGCAACCGCCATTCGGCTGTTAATGGGCGAATCTTCAGTACTGGTATTAGG
TGGACAACGCGCGCTGCCTAAACGGCTGGAAGAAGCGGGTTTTGCGTTTCGCTGGTACGATTTAGAAGAGGCGCTGGCGG
ATGTCGTTCGCTGA

Upstream 100 bases:

>100_bases
ATGCTGAAGTGGAGATCGATAAACTGCACGCGCTGCGCTACGCCGATTCGGTATCCATGACCTTAAGCTGGCAGCGTTAA
CCGCCATATCGGGAGGCTGC

Downstream 100 bases:

>100_bases
TGTGGTTTACTGCAAACATCCGCCAGTTAACTCCCGGTGTTACAGGGTTAGTGGCTTTGCGCGATAAGATCGTCTGGTGA
AAGTCGGGTCAGCGTCAGGA

Product: NAD dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNIVITGGTGLIGRHLIPRLLELGHQITVMTRNPQKASSVLGPRVTLWQGLADQSNLNGIDAVINLAGEPIADKRWTHEQ
KERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGDLGEVVVTEEEPPHNKFTHKLCARWEEIACRAQSDKTRVCL
LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRGPFNMVSPYPIRNEQFAHALGHA
LHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALADVVR

Sequences:

>Translated_297_residues
MNIVITGGTGLIGRHLIPRLLELGHQITVMTRNPQKASSVLGPRVTLWQGLADQSNLNGIDAVINLAGEPIADKRWTHEQ
KERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGDLGEVVVTEEEPPHNKFTHKLCARWEEIACRAQSDKTRVCL
LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRGPFNMVSPYPIRNEQFAHALGHA
LHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALADVVR
>Mature_297_residues
MNIVITGGTGLIGRHLIPRLLELGHQITVMTRNPQKASSVLGPRVTLWQGLADQSNLNGIDAVINLAGEPIADKRWTHEQ
KERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGDLGEVVVTEEEPPHNKFTHKLCARWEEIACRAQSDKTRVCL
LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRGPFNMVSPYPIRNEQFAHALGHA
LHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALADVVR

Specific function: Unknown

COG id: COG1090

COG function: function code R; Predicted nucleoside-diphosphate sugar epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. SDR39U1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI116812630, Length=301, Percent_Identity=35.8803986710963, Blast_Score=176, Evalue=2e-44,
Organism=Escherichia coli, GI1788642, Length=297, Percent_Identity=98.6531986531986, Blast_Score=601, Evalue=1e-173,
Organism=Drosophila melanogaster, GI28573846, Length=296, Percent_Identity=30.0675675675676, Blast_Score=161, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013549
- InterPro:   IPR001509
- InterPro:   IPR016040
- InterPro:   IPR010099 [H]

Pfam domain/function: PF08338 DUF1731; PF01370 Epimerase [H]

EC number: NA

Molecular weight: Translated: 32758; Mature: 32758

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVITGGTGLIGRHLIPRLLELGHQITVMTRNPQKASSVLGPRVTLWQGLADQSNLNGI
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCHHHHHCCCCCCCCCHH
DAVINLAGEPIADKRWTHEQKERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGD
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
LGEVVVTEEEPPHNKFTHKLCARWEEIACRAQSDKTRVCLLRTGVVLAPDGGILGKMLPP
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCHHCCCCC
FRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRGPFNMVSPYPIRNEQFAHALGHA
HHCCCCCCCCCCCEEEEEEEHHHHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
LHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALADVVR
HCCCEEEECCHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCEEEEECHHHHHHHHCC
>Mature Secondary Structure
MNIVITGGTGLIGRHLIPRLLELGHQITVMTRNPQKASSVLGPRVTLWQGLADQSNLNGI
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCHHHHHCCCCCCCCCHH
DAVINLAGEPIADKRWTHEQKERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGD
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCC
LGEVVVTEEEPPHNKFTHKLCARWEEIACRAQSDKTRVCLLRTGVVLAPDGGILGKMLPP
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEECCCCCCHHCCCCC
FRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRGPFNMVSPYPIRNEQFAHALGHA
HHCCCCCCCCCCCEEEEEEEHHHHHHHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
LHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALADVVR
HCCCEEEECCHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCEEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]