Definition Escherichia coli O157:H7 str. EC4115, complete genome.
Accession NC_011353
Length 5,572,075

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The map label for this gene is yahD [H]

Identifier: 209400607

GI number: 209400607

Start: 390657

End: 391262

Strand: Direct

Name: yahD [H]

Synonym: ECH74115_0382

Alternate gene names: 209400607

Gene position: 390657-391262 (Clockwise)

Preceding gene: 209396993

Following gene: 209397182

Centisome position: 7.01

GC content: 46.04

Gene sequence:

>606_bases
ATGAGTATAAAAAATCTACCTGCCGACTATTTATTGGCTGCACAACAGGGTGATATCGATAAAGTAAAAACCTGCCTTGC
GCTGGGTGTCGATATTAATACCTGCGATCGTCAGGGGAAAACGGCAATTACGCTGGCAAGTTTATATCAGCAATATGCTT
GCGTTCAGGCATTAATTGATGCCGGAGCGGATATTAATAAGCAAGATCATACCTGTTTAAATCCTTTTTTAATTAGCTGT
CTGAACGGTGATTTAACGCTGCTACGAATTATTTTACCGGCTAAACCAGACCTTAATTGCGTCACCCGTTTTGGCGGTGT
CGGCCTGACGCCTGCCTGTGAAAAAGGCCATTTAAGTATTGTAAAAGAGCTTTTGGCGCATACGGAAATTAACGTTAACC
AGACCAACCATGTTGGCTGGACGCCACTACTGGAAGCGATTGTGCTTAACGATGGCGGGATTAAACAGCAGGCGATTGTG
CAGTTATTGCTGGAACACGGTGCCAGCCCGCATCTGACCGATAAATATGGCAAAACGCCACTGGAACTGGCGCGGGAACG
GGGCTTTGAAGAGATTGCGCAGTTACTGATTGCCGCAGGTGCATAA

Upstream 100 bases:

>100_bases
GGCGAAATACGGCGAATTAAATTTAAGCGGGTTCTTTTATCAGATTATCGTTGCTATTCTCAATTCATCGAAAACAGCCA
CAAAAACCAGGGGAATGTGA

Downstream 100 bases:

>100_bases
ACCGGGAGGCTTGCTATCAACACACCAGAAAAACGGTGTGTGTGGGCGCTAACTGCGGATGCGGATTTTCTGGCGCAGCG
AGGGCAAGGACAGGTTGAAC

Product: ankyrin repeat protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MSIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAITLASLYQQYACVQALIDAGADINKQDHTCLNPFLISC
LNGDLTLLRIILPAKPDLNCVTRFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
QLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA

Sequences:

>Translated_201_residues
MSIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAITLASLYQQYACVQALIDAGADINKQDHTCLNPFLISC
LNGDLTLLRIILPAKPDLNCVTRFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
QLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA
>Mature_200_residues
SIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAITLASLYQQYACVQALIDAGADINKQDHTCLNPFLISCL
NGDLTLLRIILPAKPDLNCVTRFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIVQ
LLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA

Specific function: Unknown

COG id: COG0666

COG function: function code R; FOG: Ankyrin repeat

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 ANK repeats [H]

Homologues:

Organism=Homo sapiens, GI268607595, Length=190, Percent_Identity=28.4210526315789, Blast_Score=87, Evalue=8e-18,
Organism=Homo sapiens, GI62988328, Length=190, Percent_Identity=28.4210526315789, Blast_Score=87, Evalue=9e-18,
Organism=Homo sapiens, GI10863929, Length=194, Percent_Identity=30.4123711340206, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI68131557, Length=189, Percent_Identity=30.1587301587302, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI24233530, Length=188, Percent_Identity=29.2553191489362, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI304361760, Length=180, Percent_Identity=30, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI304361757, Length=180, Percent_Identity=30, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI38683816, Length=191, Percent_Identity=27.7486910994764, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI38683807, Length=191, Percent_Identity=27.7486910994764, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI157743284, Length=189, Percent_Identity=26.984126984127, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI55741641, Length=188, Percent_Identity=30.3191489361702, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI52426735, Length=188, Percent_Identity=28.7234042553192, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI255982572, Length=194, Percent_Identity=28.8659793814433, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI7705831, Length=194, Percent_Identity=28.8659793814433, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI70780355, Length=253, Percent_Identity=24.901185770751, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI46519147, Length=190, Percent_Identity=32.1052631578947, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI37620163, Length=190, Percent_Identity=32.1052631578947, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI70780359, Length=253, Percent_Identity=24.901185770751, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI52426737, Length=262, Percent_Identity=24.8091603053435, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI70780357, Length=253, Percent_Identity=24.901185770751, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI188595682, Length=262, Percent_Identity=24.8091603053435, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI70780353, Length=253, Percent_Identity=24.901185770751, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI215598574, Length=253, Percent_Identity=24.901185770751, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI32967601, Length=188, Percent_Identity=27.1276595744681, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI116875852, Length=186, Percent_Identity=30.6451612903226, Blast_Score=70, Evalue=9e-13,
Organism=Homo sapiens, GI46519151, Length=194, Percent_Identity=28.8659793814433, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI46519154, Length=194, Percent_Identity=28.8659793814433, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI39812133, Length=174, Percent_Identity=29.3103448275862, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI224809472, Length=193, Percent_Identity=31.6062176165803, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI224809470, Length=193, Percent_Identity=31.6062176165803, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI224809468, Length=193, Percent_Identity=31.6062176165803, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI224809478, Length=193, Percent_Identity=31.6062176165803, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI224809474, Length=193, Percent_Identity=31.6062176165803, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI224809476, Length=193, Percent_Identity=31.6062176165803, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI89363047, Length=190, Percent_Identity=26.8421052631579, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI148596917, Length=173, Percent_Identity=26.5895953757225, Blast_Score=67, Evalue=8e-12,
Organism=Homo sapiens, GI70995267, Length=172, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI118150656, Length=175, Percent_Identity=32, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI96975023, Length=191, Percent_Identity=27.7486910994764, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI224465233, Length=195, Percent_Identity=27.1794871794872, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI34304381, Length=194, Percent_Identity=27.319587628866, Blast_Score=64, Evalue=6e-11,
Organism=Homo sapiens, GI34304379, Length=194, Percent_Identity=27.319587628866, Blast_Score=64, Evalue=6e-11,
Organism=Homo sapiens, GI156142197, Length=195, Percent_Identity=28.2051282051282, Blast_Score=64, Evalue=7e-11,
Organism=Homo sapiens, GI156142199, Length=195, Percent_Identity=28.2051282051282, Blast_Score=64, Evalue=8e-11,
Organism=Escherichia coli, GI1786511, Length=201, Percent_Identity=99.5024875621891, Blast_Score=405, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI71981411, Length=220, Percent_Identity=28.6363636363636, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71981414, Length=222, Percent_Identity=28.8288288288288, Blast_Score=73, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25145251, Length=222, Percent_Identity=28.8288288288288, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71981389, Length=222, Percent_Identity=28.8288288288288, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17542700, Length=222, Percent_Identity=28.8288288288288, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI212646031, Length=203, Percent_Identity=28.0788177339901, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI212646035, Length=203, Percent_Identity=28.0788177339901, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI212646033, Length=203, Percent_Identity=28.0788177339901, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI45551135, Length=191, Percent_Identity=31.413612565445, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45550479, Length=191, Percent_Identity=31.413612565445, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI28573593, Length=191, Percent_Identity=31.413612565445, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281363919, Length=191, Percent_Identity=31.413612565445, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI221330474, Length=191, Percent_Identity=31.413612565445, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI221330482, Length=191, Percent_Identity=31.413612565445, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI221330480, Length=191, Percent_Identity=31.413612565445, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI221330476, Length=191, Percent_Identity=31.413612565445, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI221330478, Length=191, Percent_Identity=31.413612565445, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24581260, Length=201, Percent_Identity=31.3432835820896, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24581258, Length=201, Percent_Identity=31.3432835820896, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281359521, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281359519, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28558752, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28558750, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28558756, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28558754, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI161082106, Length=190, Percent_Identity=28.9473684210526, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI161082096, Length=190, Percent_Identity=28.9473684210526, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI161082081, Length=190, Percent_Identity=28.9473684210526, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI161082110, Length=190, Percent_Identity=28.9473684210526, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI161082099, Length=190, Percent_Identity=28.9473684210526, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI161082085, Length=190, Percent_Identity=28.9473684210526, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161082089, Length=190, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI161082092, Length=190, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28571867, Length=192, Percent_Identity=30.2083333333333, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI28571865, Length=192, Percent_Identity=30.2083333333333, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24650843, Length=225, Percent_Identity=26.2222222222222, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281366282, Length=196, Percent_Identity=27.5510204081633, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281366284, Length=196, Percent_Identity=27.5510204081633, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161084156, Length=196, Percent_Identity=27.5510204081633, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161084152, Length=196, Percent_Identity=27.5510204081633, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281366286, Length=196, Percent_Identity=27.5510204081633, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002110
- InterPro:   IPR020683 [H]

Pfam domain/function: PF00023 Ank [H]

EC number: NA

Molecular weight: Translated: 21629; Mature: 21498

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50088 ANK_REPEAT ; PS50297 ANK_REP_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAITLASLYQQYACVQALID
CCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AGADINKQDHTCLNPFLISCLNGDLTLLRIILPAKPDLNCVTRFGGVGLTPACEKGHLSI
CCCCCCCCCCHHHHHHHHHHHCCCCEEHHEECCCCCCHHHHHHCCCCCCCCCCCCCCHHH
VKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIVQLLLEHGASPHLTDKYGKTP
HHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCCH
LELARERGFEEIAQLLIAAGA
HHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAITLASLYQQYACVQALID
CCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AGADINKQDHTCLNPFLISCLNGDLTLLRIILPAKPDLNCVTRFGGVGLTPACEKGHLSI
CCCCCCCCCCHHHHHHHHHHHCCCCEEHHEECCCCCCHHHHHHCCCCCCCCCCCCCCHHH
VKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIVQLLLEHGASPHLTDKYGKTP
HHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHCCCCH
LELARERGFEEIAQLLIAAGA
HHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]