| Definition | Escherichia coli O157:H7 str. EC4115, complete genome. |
|---|---|
| Accession | NC_011353 |
| Length | 5,572,075 |
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The map label for this gene is xseA [H]
Identifier: 209400584
GI number: 209400584
Start: 3454491
End: 3455861
Strand: Direct
Name: xseA [H]
Synonym: ECH74115_3734
Alternate gene names: 209400584
Gene position: 3454491-3455861 (Clockwise)
Preceding gene: 209395734
Following gene: 209398755
Centisome position: 62.0
GC content: 53.54
Gene sequence:
>1371_bases ATGTTACCTTCTCAATCCCCTGCAATTTTTACCGTTAGTCGCCTGAATCAAACGGTTCGTCTGCTGCTTGAGCATGAGAT GGGACAGGTTTGGATCAGCGGCGAAATCTCTAATTTCACACAACCGGCTTCCGGTCACTGGTACTTTACACTCAAAGACG ACACCGCCCAGGTACGCTGCGCGATGTTCCGCAACAGCAACCGCCGGGTGACCTTCCGCCCACAGCATGGGCAACAAGTT TTAGTTCGCGCCAATATTACGCTCTACGAGCCGCGCGGCGACTACCAGATAATCGTTGAGAGTATGCAGCCGGCCGGTGA AGGGCTGCTGCAACAGAAGTACGAACAGCTCAAAGCGAAGTTGCAGGCTGAAGGATTGTTCGATCTGCAATACAAAAAAC CACTTCCCTCCCCTGCGCATTGCGTTGGTGTGATCACCTCAAAAACCGGTGCTGCGCTACATGATATTTTGCATGTGTTA AAACGTCGCGATCCTTCTCTGCCGGTGATCATCTACCCCACCGCCGTTCAGGGCGATGACGCGCCGGGGCAAATTGTTCG CGCCATTGAACTGGCGAATCAGTGCAATGAGTGCGACGTGTTGATCGTTGGGCGCGGCGGCGGTTCGCTGGAAGATTTAT GGAGTTTTAACGACGAACGCGTAGCGCGGGCGATTTTTGCCAGCCGCATTCCGGTCGTCAGCGCCGTCGGGCATGAGACG GATGTGACCATTGCCGATTTTGTTGCCGATCTGCGTGCACCAACACCGTCGGCTGCCGCCGAAGTGGTGAGCCGTAATCA GCAAGAGTTACTGCGCCAGGTGCAATCGACCCGTCAACGGCTGGAGATGGCGATGGATTATTATCTCGCCAACCGCACAC GTCGCTTTACGCAAATTCATCACCGATTACAGCAACAGCATCCGCAGCTCCGGCTGGCACGCCAGCAAACCATGCTTGAA CGCCTGCAAAAACGGATGAGCTTTGCGCTGGAAAATCAACTTAAGCGTGCCGGGCAACAGCAGCAGCGATTAACACAGCG GCTGAATCAGCAAAATCCACAGCCGAAGATTCATCGCGCGCAAACGCGCATTCAGCAACTGGAATATCGTTTAGCAGAAA CCCTGCGCGCACAGCTTAGCGCCACGCGTGAACGTTTCGGTAATGCAGTAACGCACCTCGAAGCCGTAAGCCCACTGTCA ACGCTGGCGCGTGGATACAGCGTTACTACTGCTACTGACGGCAAGGTACTGAAAAAAGTGAAGCAGGTTAAAGCGGGTGA AATGCTAACCACACGTCTGGAAGACGGCTGGGTAGAAAGTGAAGTAAAAAACATCCAGCCGGTAAAAAAATCGCGTAAAA AAGTGCATTAA
Upstream 100 bases:
>100_bases GATTGCATCTACCCCTTTTTGCAAAAAATGCTTGCTATCCCCGAAGGGCGGGTTACTATCGACTGAATAACCTGCTGATT TAGAATTTGATCTCGCTCAC
Downstream 100 bases:
>100_bases GCCAGCACGAATTCAACGCGTTTTTTCGATATCAAGCCATGCCCGTGCTGACAGAAGTAATCTACCGCACCGCAGGCTTT TAACACCTGCAACGGTTGAT
Product: exodeoxyribonuclease VII large subunit
Products: NA
Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]
Number of amino acids: Translated: 456; Mature: 456
Protein sequence:
>456_residues MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQV LVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDLQYKKPLPSPAHCVGVITSKTGAALHDILHVL KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANQCNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHET DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLE RLQKRMSFALENQLKRAGQQQQRLTQRLNQQNPQPKIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLS TLARGYSVTTATDGKVLKKVKQVKAGEMLTTRLEDGWVESEVKNIQPVKKSRKKVH
Sequences:
>Translated_456_residues MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQV LVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDLQYKKPLPSPAHCVGVITSKTGAALHDILHVL KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANQCNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHET DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLE RLQKRMSFALENQLKRAGQQQQRLTQRLNQQNPQPKIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLS TLARGYSVTTATDGKVLKKVKQVKAGEMLTTRLEDGWVESEVKNIQPVKKSRKKVH >Mature_456_residues MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQV LVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDLQYKKPLPSPAHCVGVITSKTGAALHDILHVL KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANQCNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHET DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLE RLQKRMSFALENQLKRAGQQQQRLTQRLNQQNPQPKIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLS TLARGYSVTTATDGKVLKKVKQVKAGEMLTTRLEDGWVESEVKNIQPVKKSRKKVH
Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]
COG id: COG1570
COG function: function code L; Exonuclease VII, large subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the xseA family [H]
Homologues:
Organism=Escherichia coli, GI1788856, Length=456, Percent_Identity=98.4649122807018, Blast_Score=925, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003753 - InterPro: IPR020579 - InterPro: IPR004365 [H]
Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]
EC number: =3.1.11.6 [H]
Molecular weight: Translated: 51735; Mature: 51735
Theoretical pI: Translated: 10.47; Mature: 10.47
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRC CCCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCHHHHH AMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAK HHHCCCCCEEEECCCCCCEEEEEEEEEEECCCCCHHHHEEHHCCCCCHHHHHHHHHHHHH LQAEGLFDLQYKKPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDD HHHCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCC APGQIVRAIELANQCNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHET CHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCC DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIH CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HRLQQQHPQLRLARQQTMLERLQKRMSFALENQLKRAGQQQQRLTQRLNQQNPQPKIHRA HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH QTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLSTLARGYSVTTATDGKVLKKV HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHH KQVKAGEMLTTRLEDGWVESEVKNIQPVKKSRKKVH HHHHCCHHHHHHHHCCHHHHHHHHCHHHHHHHCCCC >Mature Secondary Structure MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRC CCCCCCCCEEEHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEEECCCHHHHH AMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAK HHHCCCCCEEEECCCCCCEEEEEEEEEEECCCCCHHHHEEHHCCCCCHHHHHHHHHHHHH LQAEGLFDLQYKKPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDD HHHCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCC APGQIVRAIELANQCNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHET CHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCC DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIH CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HRLQQQHPQLRLARQQTMLERLQKRMSFALENQLKRAGQQQQRLTQRLNQQNPQPKIHRA HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH QTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLSTLARGYSVTTATDGKVLKKV HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHH KQVKAGEMLTTRLEDGWVESEVKNIQPVKKSRKKVH HHHHCCHHHHHHHHCCHHHHHHHHCHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA