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The map label for this gene is chbC [H]

Identifier: 209400404

GI number: 209400404

Start: 2325661

End: 2327019

Strand: Reverse

Name: chbC [H]

Synonym: ECH74115_2455

Alternate gene names: 209400404

Gene position: 2327019-2325661 (Counterclockwise)

Preceding gene: 209398244

Following gene: 209398511

Centisome position: 41.76

GC content: 49.08

Gene sequence:

>1359_bases
ATGAGTAATGTTATTGCATCGCTTGAAAAGGTACTCCTCCCTTTTGCAGTTAAAATAGGAAAGCAGCCACACGTTAATGC
AATCAAAAATGGCTTTATTCGCTTAATGCCGTTAACCCTTGCGGGGGCCATGTTTGTATTAATTAACAACGTTTTTCTAA
GCTTTGGGGAGGGGTCGTTTTTTTATTCCTTAGGTATTCGCCTCGACGCCTCAACCATTGAAACACTTAATGGTCTGAAA
GGTATTGGCGGCAACGTATATAACGGAACATTAGGGATAATGTCTTTAATGGCACCGTTCTTTATTGGCATGGCGCTGGC
AGAAGAGCGTAAAGTCGATGCGCTGGCGGCTGGGTTGTTATCCGTTGCAGCATTTATGACCGTCACCCCATATAGTGTCG
GTGAGGCCTATGCGGTTGGCGCAAACTGGTTAGGTGGGGCGAATATCATCTCCGGGATTATTATTGGCCTGGTGGTGGCA
GAAATGTTTACCTTTATTGTCCGCCGCAATTGGGTCATTAAACTGCCCGACAGCGTACCTGCTTCAGTATCGCGTTCCTT
CTCGGCATTAATTCCCGGCTTTATTATTCTTTCCGTGATGGGGATTATTGCCTGGGCGTTGAATACCTGGGGCACCAACT
TCCATCAGATCATTATGGATACCATCTCAACCCCACTGGCATCGTTGGGTAGCGTGGTGGGCTGGGCCTATGTGATCTTT
GTTCCACTGCTCTGGTTCTTCGGTATTCATGGCGCGCTGGCGCTGACCGCACTGGACAACGGCATTATGACGCCGTGGGC
GCTGGAAAATATCGCGACCTATCAGCAATATGGTTCCGTCGAAGCGGCGCTGGCAGCCGGTAAGACCTTCCATATCTGGG
CCAAGCCGATGCTGGACTCCTTTATTTTCCTTGGAGGCAGTGGTGCGACTTTAGGCCTGATCCTGGCTATCTTTATTGCC
TCTCGCCGTGCTGATTATCGTCAGGTGGCAAAACTGGCGCTGCCGTCCGGCATCTTCCAGATTAACGAACCGATTCTGTT
TGGTCTGCCAATTATCATGAACCCGGTGATGTTTATCCCGTTTGTACTGGTACAACCGATTCTGGCGGCAATCACCCTGG
CAGCGTACTACATGGGCATTATTCCTCCGGTGACCAATATTGCACCGTGGACCATGCCAACCGGTCTGGGAGCCTTCTTT
AACACCAACGGTAGCGTCGTCGCATTGCTGGTTGCACTCTTCAACCTTGGTATCGCAACGTTAATTTATCTGCCCTTTGT
TGTGGTGGCTAACAAAGCACAAAATGCGATTGATAAAGAAGAGAGCGAAGAAGATATCGCTAACGCCCTGAAATTTTAA

Upstream 100 bases:

>100_bases
AGCCGCAGCAAATTAATTTATTTTAAATTTTCCCGTCAAAGAGTTATTTCATAAATCAATACCGCAATATTTAAATTGCG
GTTTTTAAGGGTATTTTTCT

Downstream 100 bases:

>100_bases
TCGATGCCGGTACGGGTAATCGTGCCGGTAAGAAAAGAGAGGAACGATGTATGATGGATCTCGATAATATTCCCGATACG
CAAACGGAAGCTGAAGAGCT

Product: PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Chb; PTS system N,N'-diacetylchitobiose-specific EIIC component [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAMFVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLK
GIGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVA
EMFTFIVRRNWVIKLPDSVPASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQIIMDTISTPLASLGSVVGWAYVIF
VPLLWFFGIHGALALTALDNGIMTPWALENIATYQQYGSVEAALAAGKTFHIWAKPMLDSFIFLGGSGATLGLILAIFIA
SRRADYRQVAKLALPSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLAAYYMGIIPPVTNIAPWTMPTGLGAFF
NTNGSVVALLVALFNLGIATLIYLPFVVVANKAQNAIDKEESEEDIANALKF

Sequences:

>Translated_452_residues
MSNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAMFVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLK
GIGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVA
EMFTFIVRRNWVIKLPDSVPASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQIIMDTISTPLASLGSVVGWAYVIF
VPLLWFFGIHGALALTALDNGIMTPWALENIATYQQYGSVEAALAAGKTFHIWAKPMLDSFIFLGGSGATLGLILAIFIA
SRRADYRQVAKLALPSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLAAYYMGIIPPVTNIAPWTMPTGLGAFF
NTNGSVVALLVALFNLGIATLIYLPFVVVANKAQNAIDKEESEEDIANALKF
>Mature_451_residues
SNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAMFVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLKG
IGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVAE
MFTFIVRRNWVIKLPDSVPASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQIIMDTISTPLASLGSVVGWAYVIFV
PLLWFFGIHGALALTALDNGIMTPWALENIATYQQYGSVEAALAAGKTFHIWAKPMLDSFIFLGGSGATLGLILAIFIAS
RRADYRQVAKLALPSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLAAYYMGIIPPVTNIAPWTMPTGLGAFFN
TNGSVVALLVALFNLGIATLIYLPFVVVANKAQNAIDKEESEEDIANALKF

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1455

COG function: function code G; Phosphotransferase system cellobiose-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=452, Percent_Identity=99.7787610619469, Blast_Score=887, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 48361; Mature: 48230

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAMFVLINNVFLSFGEGSF
CCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHCCCCCE
FYSLGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLL
EEEEEEEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVAEMFTFIVRRNWVIKLPDSVP
HHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
ASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQIIMDTISTPLASLGSVVGWAYVIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPLLWFFGIHGALALTALDNGIMTPWALENIATYQQYGSVEAALAAGKTFHIWAKPMLDS
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCEEEEEHHHHHHH
FIFLGGSGATLGLILAIFIASRRADYRQVAKLALPSGIFQINEPILFGLPIIMNPVMFIP
HEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEECCCHHCCCHHHHHHHHHHH
FVLVQPILAAITLAAYYMGIIPPVTNIAPWTMPTGLGAFFNTNGSVVALLVALFNLGIAT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHH
LIYLPFVVVANKAQNAIDKEESEEDIANALKF
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAMFVLINNVFLSFGEGSF
CHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHCCCCCE
FYSLGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLL
EEEEEEEECHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVAEMFTFIVRRNWVIKLPDSVP
HHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
ASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQIIMDTISTPLASLGSVVGWAYVIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPLLWFFGIHGALALTALDNGIMTPWALENIATYQQYGSVEAALAAGKTFHIWAKPMLDS
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCEEEEEHHHHHHH
FIFLGGSGATLGLILAIFIASRRADYRQVAKLALPSGIFQINEPILFGLPIIMNPVMFIP
HEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEECCCHHCCCHHHHHHHHHHH
FVLVQPILAAITLAAYYMGIIPPVTNIAPWTMPTGLGAFFNTNGSVVALLVALFNLGIAT
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHH
LIYLPFVVVANKAQNAIDKEESEEDIANALKF
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2179047; 9097039; 9278503; 2092358; 9405618; 10913117 [H]