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The map label for this gene is dinF [H]

Identifier: 209400391

GI number: 209400391

Start: 5175332

End: 5176657

Strand: Direct

Name: dinF [H]

Synonym: ECH74115_5525

Alternate gene names: 209400391

Gene position: 5175332-5176657 (Clockwise)

Preceding gene: 209400985

Following gene: 209398011

Centisome position: 92.88

GC content: 55.35

Gene sequence:

>1326_bases
ATGGCATTCCTCACTTCATCTGATAAAGCACTTTGGCATCTCGCCTTACCCATGATTTTCTCCAATATCACTGTTCCGTT
GCTGGGACTGGTCGATACGGCGGTTATTGGTCATCTTGATAGTCCGGTTTATTTGGGCGGCGTGGCGGTTGGTGCAACGG
CGACCAGCTTTCTCTTTATGCTGTTGCTGTTTTTACGCATGAGCACCACCGGGCTGACTGCGCAGGCTTATGGTGCCAAA
AATCCTCAGGCATTAGCCCGTGCGCTGGTGCAACCTTTGCTGTTGGCGTTGGGGGCTGGGGCGTTAATTGCGCTGCTGCG
TACGCCGATTATCGATCTGGCGCTGCATATTGTTGGCGGTAGTGAAGCAGTCCTGGAACAGGCGCGGCGCTTTCTTGAAA
TCCGCTGGTTAAGCGCACCGGCGTCGCTGGCGAATCTGGTATTACTTGGTTGGTTACTCGGCGTGCAATATGCCCGTGCG
CCAGTAATTTTGTTAGTGGTCGGCAATATCCTCAACATTGTGCTGGATGTCTGGCTGGTGATGGGACTGCATATGAACGT
GCGGGGCGCGGCGCTGGCGACGGTTATTGCGGAATATGCAACATTGCTGATTGGTCTGCTAATGGTGCGTAAAATCCTCA
AACTACGCGGAATCTCCGGCGAAATGCTGAAAACTTCCTGGCGAGGAAACTTCCGTCGCTTGCTGGCACTTAACCGCGAT
ATCATGCTGCGCTCGCTGTTGTTGCAACTCTGTTTCGGCGCGATCACCGTACTTGGCGCGCGACTGGGGAGTGACATTAT
CGCTGTTAACGCGGTTCTGATGACGCTACTCACCTTTACCGCCTATGCGCTGGACGGTTTTGCCTACGCGGTTGAAGCAC
ATTCCGGTCAGGCATACGGTGCGCGCGACGGTAGCCAGTTGCTGGATGTCTGGCGGGCAGCATGCCGCCAGTCGGGGATC
GTAGCGTTACTGTTTTCGGTGGTTTATTTGCTGGCAGGGGAACACATCATTGCGTTACTGGCGTCGTTAACCCAGATTCA
GCAGCTGGCCGACCGCTATCTTATCTGGCAGGTGATTTTGCCGTTGGTCGGCGTCTGGTGTTATCTGCTGGACGGCATGT
TTATAGGCGCAACGCGTGCTGCTGAAATGCGTAACAGTATGGCGGTGGCCGCCGCAGGTTTTGCGCTGACGCTCCTTACG
CTGCCGTGGCTGGGTAATCATGGTTTGTGGTTGGCGTTAACCGTCTTTCTGGCGTTGCGCGGGCTTTCTCTGGCAGCTAT
CTGGCGGCGTCACTGGCGCAACGGTACCTGGTTTGCCGCAACGTGA

Upstream 100 bases:

>100_bases
CGTTATTCGCAACGGCGACTGGCTGTAACATATCTCTGAGACCGCGATGCCGCTTGGCGTCGCGGTTTGTTTTTCATCTC
TCTTCATCAGGCTTGTCTGC

Downstream 100 bases:

>100_bases
CGGTTAAAAATTCTGAATAAATAATCCTAAGCCAAATTGCTGACTACACTTAATCTCACGTTCAGAAGAAAAGTGAACGT
ACTCTCATTCACAACCTAAC

Product: DNA-damage-inducible SOS response protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAK
NPQALARALVQPLLLALGAGALIALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
PVILLVVGNILNIVLDVWLVMGLHMNVRGAALATVIAEYATLLIGLLMVRKILKLRGISGEMLKTSWRGNFRRLLALNRD
IMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGI
VALLFSVVYLLAGEHIIALLASLTQIQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLT
LPWLGNHGLWLALTVFLALRGLSLAAIWRRHWRNGTWFAAT

Sequences:

>Translated_441_residues
MAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAK
NPQALARALVQPLLLALGAGALIALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
PVILLVVGNILNIVLDVWLVMGLHMNVRGAALATVIAEYATLLIGLLMVRKILKLRGISGEMLKTSWRGNFRRLLALNRD
IMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGI
VALLFSVVYLLAGEHIIALLASLTQIQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLT
LPWLGNHGLWLALTVFLALRGLSLAAIWRRHWRNGTWFAAT
>Mature_440_residues
AFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAKN
PQALARALVQPLLLALGAGALIALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAP
VILLVVGNILNIVLDVWLVMGLHMNVRGAALATVIAEYATLLIGLLMVRKILKLRGISGEMLKTSWRGNFRRLLALNRDI
MLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIV
ALLFSVVYLLAGEHIIALLASLTQIQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLTL
PWLGNHGLWLALTVFLALRGLSLAAIWRRHWRNGTWFAAT

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=441, Percent_Identity=98.4126984126984, Blast_Score=846, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47680; Mature: 47549

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFM
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHH
LLLFLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGALIALLRTPIIDLALHIVGG
HHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVGNILNIVLDVWLV
CHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
MGLHMNVRGAALATVIAEYATLLIGLLMVRKILKLRGISGEMLKTSWRGNFRRLLALNRD
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHH
IMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCC
ARDGSQLLDVWRAACRQSGIVALLFSVVYLLAGEHIIALLASLTQIQQLADRYLIWQVIL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLTLPWLGNHGLWLALTVFLALR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GLSLAAIWRRHWRNGTWFAAT
HHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure 
AFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFM
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHH
LLLFLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGALIALLRTPIIDLALHIVGG
HHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPVILLVVGNILNIVLDVWLV
CHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
MGLHMNVRGAALATVIAEYATLLIGLLMVRKILKLRGISGEMLKTSWRGNFRRLLALNRD
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHH
IMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCC
ARDGSQLLDVWRAACRQSGIVALLFSVVYLLAGEHIIALLASLTQIQQLADRYLIWQVIL
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLTLPWLGNHGLWLALTVFLALR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GLSLAAIWRRHWRNGTWFAAT
HHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]