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The map label for this gene is trg [H]

Identifier: 209400342

GI number: 209400342

Start: 1924797

End: 1926209

Strand: Direct

Name: trg [H]

Synonym: ECH74115_2026

Alternate gene names: 209400342

Gene position: 1924797-1926209 (Clockwise)

Preceding gene: 209399017

Following gene: 209396192

Centisome position: 34.54

GC content: 51.59

Gene sequence:

>1413_bases
ATGATTCAGGCCGGGGCTGCGAGTCGTATTGCGGAAATGGAAGCAATGAAGCGAAATATTGCGCAAGCCGAATCGGAGAT
TAAACAGTCGCAGCAAGGTTATCGTGCTTATCAGAATCGGCCGGTGAAAACACCTGCTGATGAAGCCCTCGACACTGAAT
TAAATCAACGCTTTCAGGCTTATATCACGGGTATGCAACCTATGTTGAAATATGCCAAAAATGGCATGTTTGAAGCGATT
ATCAATCATGAAAGTGAGCAGATCCGAACGCTGGATAATGCTTATACCGATATTTTGAACAAAGCCGTTAAGATACGTAG
CACCAGAGCCAACCAACTGGCGGAACTGGCCCATCAGCGCACCCGCCTGGGCGGGATGTTCATGATTGGTGCGTTTGTGC
TTGCCCTGGTCATGACGCTGATAACATTTATGGTGCTACGTCGGATCGTCATTCGTCCACTGCAACATGCCGCACAACGG
ATTGAAAAAATCGCTAGTGGCGATCTGACGATGAAGGATGAACCGGCGGGTCGTAATGAAATCGGTCGCTTAAGTCGTCA
TTTACAGCAAATGCAGCATTCACTGGGGATGACCGTAGGGACTGTTCGACAGGGTGCGGAAGAGATTTATCGTGGCACCA
GCGAAATTTCAGCTGGCAATGCGGACCTGTCATCTCGCACCGAAGAACAAGCGGCGGCTATCGAACAAACTGCCGCCAGC
ATGGAGCAACTCACTGCGACGGTGAAACAGAATGCGGATAACGCGCATTATGCCAGCAAACTGGCGCAAGAGGCTTCTAT
TAAAGCCAGCGATGGCGGGCAGACGGTTTCCGGTGTAGTAAAAACGATGGGCGCTATCTCCACGAGTTCGAAGAAAATTT
CTGAGATCACCGCCGTCATCAACAGTATTGCTTTCCAGACGAATATTCTGGCACTGAATGCTGCCGTTGAAGCTGCGCGA
GCGGGTGAGCAAGGGCGTGGATTTGCCGTTGTCGCCAGCGAAGTACGGACACTCGCAAGCCGCAGCGCCCAGGCGGCAAA
AGAAATTGAAGGCTTGATCAGTGAATCAGTCAGGTTAATTGACCTGGGATCGGATGAGGTGGCAACGGCCGGGAAAACCA
TGAGCACTATTGTTGATGCCGTCGCGAGTGTCACACATATCATGCAGGAAATTGCCGCCGCCTCGGATGAGCAAAGTAGG
GGCATAACGCAGGTTAGCCAGGCGATTTCTGAAATGGATAAGGTGACGCAACAGAATGCTTCTCTGGTAGAAGAGGCCTC
AGCGGCGGCGGTGTCCCTTGAAGAACAGGCGGCACGATTAACTGAGGCGGTGGACGTATTCCGTCTGAACAAACAATCTG
TGTTGGCAGAACCTCGCGGAGCGGGTGAACTAGTTAGTTTCGCTCCGGTGTGA

Upstream 100 bases:

>100_bases
CTGGCAGGCCGATCGCGATCAGCGTGATGTTACTGCGGAGATTGAGATTCGGACCGGGTTAGCGAACAGTTCAGATTTTT
TGCGTTCAGCCCGGATCAAT

Downstream 100 bases:

>100_bases
AAATGTTAAAGGAGGGATCGACAGATCCCTTCACCTTTCAGAACGGCATTGATTTTCGAATAGCGTTAATCATCAACTGG
CAACCAGAAGAGAACGTCGC

Product: methyl-accepting chemotaxis protein III

Products: NA

Alternate protein names: MCP-III; Ribose and galactose chemoreceptor protein [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MIQAGAASRIAEMEAMKRNIAQAESEIKQSQQGYRAYQNRPVKTPADEALDTELNQRFQAYITGMQPMLKYAKNGMFEAI
INHESEQIRTLDNAYTDILNKAVKIRSTRANQLAELAHQRTRLGGMFMIGAFVLALVMTLITFMVLRRIVIRPLQHAAQR
IEKIASGDLTMKDEPAGRNEIGRLSRHLQQMQHSLGMTVGTVRQGAEEIYRGTSEISAGNADLSSRTEEQAAAIEQTAAS
MEQLTATVKQNADNAHYASKLAQEASIKASDGGQTVSGVVKTMGAISTSSKKISEITAVINSIAFQTNILALNAAVEAAR
AGEQGRGFAVVASEVRTLASRSAQAAKEIEGLISESVRLIDLGSDEVATAGKTMSTIVDAVASVTHIMQEIAAASDEQSR
GITQVSQAISEMDKVTQQNASLVEEASAAAVSLEEQAARLTEAVDVFRLNKQSVLAEPRGAGELVSFAPV

Sequences:

>Translated_470_residues
MIQAGAASRIAEMEAMKRNIAQAESEIKQSQQGYRAYQNRPVKTPADEALDTELNQRFQAYITGMQPMLKYAKNGMFEAI
INHESEQIRTLDNAYTDILNKAVKIRSTRANQLAELAHQRTRLGGMFMIGAFVLALVMTLITFMVLRRIVIRPLQHAAQR
IEKIASGDLTMKDEPAGRNEIGRLSRHLQQMQHSLGMTVGTVRQGAEEIYRGTSEISAGNADLSSRTEEQAAAIEQTAAS
MEQLTATVKQNADNAHYASKLAQEASIKASDGGQTVSGVVKTMGAISTSSKKISEITAVINSIAFQTNILALNAAVEAAR
AGEQGRGFAVVASEVRTLASRSAQAAKEIEGLISESVRLIDLGSDEVATAGKTMSTIVDAVASVTHIMQEIAAASDEQSR
GITQVSQAISEMDKVTQQNASLVEEASAAAVSLEEQAARLTEAVDVFRLNKQSVLAEPRGAGELVSFAPV
>Mature_470_residues
MIQAGAASRIAEMEAMKRNIAQAESEIKQSQQGYRAYQNRPVKTPADEALDTELNQRFQAYITGMQPMLKYAKNGMFEAI
INHESEQIRTLDNAYTDILNKAVKIRSTRANQLAELAHQRTRLGGMFMIGAFVLALVMTLITFMVLRRIVIRPLQHAAQR
IEKIASGDLTMKDEPAGRNEIGRLSRHLQQMQHSLGMTVGTVRQGAEEIYRGTSEISAGNADLSSRTEEQAAAIEQTAAS
MEQLTATVKQNADNAHYASKLAQEASIKASDGGQTVSGVVKTMGAISTSSKKISEITAVINSIAFQTNILALNAAVEAAR
AGEQGRGFAVVASEVRTLASRSAQAAKEIEGLISESVRLIDLGSDEVATAGKTMSTIVDAVASVTHIMQEIAAASDEQSR
GITQVSQAISEMDKVTQQNASLVEEASAAAVSLEEQAARLTEAVDVFRLNKQSVLAEPRGAGELVSFAPV

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=470, Percent_Identity=98.2978723404255, Blast_Score=919, Evalue=0.0,
Organism=Escherichia coli, GI1788195, Length=324, Percent_Identity=62.037037037037, Blast_Score=344, Evalue=6e-96,
Organism=Escherichia coli, GI2367378, Length=452, Percent_Identity=47.787610619469, Blast_Score=335, Evalue=5e-93,
Organism=Escherichia coli, GI1788194, Length=333, Percent_Identity=54.6546546546547, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1789453, Length=324, Percent_Identity=39.8148148148148, Blast_Score=219, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 50508; Mature: 50508

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50885 HAMP ; PS00538 CHEMOTAXIS_TRANSDUC_1 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQAGAASRIAEMEAMKRNIAQAESEIKQSQQGYRAYQNRPVKTPADEALDTELNQRFQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
YITGMQPMLKYAKNGMFEAIINHESEQIRTLDNAYTDILNKAVKIRSTRANQLAELAHQR
HHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRLGGMFMIGAFVLALVMTLITFMVLRRIVIRPLQHAAQRIEKIASGDLTMKDEPAGRNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHH
IGRLSRHLQQMQHSLGMTVGTVRQGAEEIYRGTSEISAGNADLSSRTEEQAAAIEQTAAS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHH
MEQLTATVKQNADNAHYASKLAQEASIKASDGGQTVSGVVKTMGAISTSSKKISEITAVI
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
NSIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLASRSAQAAKEIEGLISESVRLI
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
DLGSDEVATAGKTMSTIVDAVASVTHIMQEIAAASDEQSRGITQVSQAISEMDKVTQQNA
ECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHH
SLVEEASAAAVSLEEQAARLTEAVDVFRLNKQSVLAEPRGAGELVSFAPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIQAGAASRIAEMEAMKRNIAQAESEIKQSQQGYRAYQNRPVKTPADEALDTELNQRFQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
YITGMQPMLKYAKNGMFEAIINHESEQIRTLDNAYTDILNKAVKIRSTRANQLAELAHQR
HHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRLGGMFMIGAFVLALVMTLITFMVLRRIVIRPLQHAAQRIEKIASGDLTMKDEPAGRNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHH
IGRLSRHLQQMQHSLGMTVGTVRQGAEEIYRGTSEISAGNADLSSRTEEQAAAIEQTAAS
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHCCCCCCCHHHHHHHHHHHHHHHHHH
MEQLTATVKQNADNAHYASKLAQEASIKASDGGQTVSGVVKTMGAISTSSKKISEITAVI
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
NSIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLASRSAQAAKEIEGLISESVRLI
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
DLGSDEVATAGKTMSTIVDAVASVTHIMQEIAAASDEQSRGITQVSQAISEMDKVTQQNA
ECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHH
SLVEEASAAAVSLEEQAARLTEAVDVFRLNKQSVLAEPRGAGELVSFAPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6374654; 9097039; 9278503 [H]