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The map label for this gene is cusB [H]

Identifier: 209400334

GI number: 209400334

Start: 683289

End: 684512

Strand: Direct

Name: cusB [H]

Synonym: ECH74115_0655

Alternate gene names: 209400334

Gene position: 683289-684512 (Clockwise)

Preceding gene: 209396059

Following gene: 209396317

Centisome position: 12.26

GC content: 55.88

Gene sequence:

>1224_bases
ATGAAAAAAATCGCGCTTATTATCGGCAGCATGATCGCGGGCGGTATTATTTCTGCGGCAGGTTTTACCTGGTTTGCAAA
GGCGGAACCGCCTGCAGAAAAAACGTCGACCGCAGAACGTAAAATCTTATTCTGGTACGACCCGATGTATCCCAATACGC
GGTTCGATAAACCAGGTAAATCGCCGTTTATGGATATGGATCTGGTGCCGAAATATGCCGATGAAGAGAGTTCTGCGTCT
GGTGTGCGCATTGACCCGACTCAGACGCAGAATCTGGGGGTGAAAACGGCTACCGTCACGCGCGGGCCGCTGACTTTTGC
CCAGAGTTTCCCGGCGAATGTCAGTTACAACGAGTATCAGTATGCCATTGTGCAGGCTCGCGCCGCCGGGTTTATCGACA
AGGTGTATCCGCTTACCGTGGGCGATAAAGTACAAAAGGGCGCGCCGCTTCTCGACCTGACCATTCCCGACTGGGTGGAA
GCGCAGAGTGAGTATTTACTGCTGCGCGAAACCGGCGGTACGGCGACCCAGACCGAAGGCATTCTTGAGCGGCTGCGACT
GGCGGGAATGCCGGAGGCGGATATTCGCCGCCTGATCGCCACGCAAAAAATCCAGACTCGCTTTACGCTCAAAGCACCCA
TTGATGGCGTGATCACCGCGTTTGATCTGCGCGCGGGAATGAATATCGCCAAAGATAACGTGGTAGCGAAAATTCAGGGT
ATGGACCCGGTGTGGGTCACTGCTGCGATCCCGGAGTCCATCGCCTGGCTGGTGAAAGATGCCTCGCAGTTTACGCTCAC
CGTTCCGGCGCGACCTGATAAAACACTCACCATCCGCAAATGGACGCTACTACCTGGCGTGGATGCCGCGACCCGCACGC
TGCAGCTGCGTCTGGAAGTCGACAACGCCGACGAGGCGCTAAAACCGGGAATGAACGCCTGGTTGCAACTCAATACCGCC
AGCGAACCGATGCTGCTCATTCCGTCACAGGCGCTGATTGATACCGGCAGCGAACAGCGGGTGATTACCGTTGATGCCGA
CGGGCGCTTTGTACCAAAACGCGTTGCCGTTTTCCAGGCATCGCAAGGTGTCACCGCATTACGCTCTGGTCTGGCGGAAG
GTGAAAAGGTGGTTTCCAGCGGCCTGTTCCTGATTGATTCCGAAGCCAATATTTCTGGCGCACTGGAGCGGATGCGCTCT
GAAAGTGCTACCCATGCGCATTGA

Upstream 100 bases:

>100_bases
AATTAAAACCGGCGACAAAGTGGCGTTTAATTTTGTCCAGCAGGGCAACCTTTCTTTATTACAGGATATTAAAGTCAGCC
AGTAACCCAGGTTTAATGAG

Downstream 100 bases:

>100_bases
GGGAATAACCAATGATTGAATGGATTATTCGTCGCTCGGTGGCGAACCGTTTTTTGGTGCTGATGGGCGCGTTATTTCTG
AGTATCTGGGGCACCTGGAC

Product: copper/silver efflux system membrane fusion protein CusB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MKKIALIIGSMIAGGIISAAGFTWFAKAEPPAEKTSTAERKILFWYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSAS
GVRIDPTQTQNLGVKTATVTRGPLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGAPLLDLTIPDWVE
AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKIQG
MDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTLTIRKWTLLPGVDAATRTLQLRLEVDNADEALKPGMNAWLQLNTA
SEPMLLIPSQALIDTGSEQRVITVDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANISGALERMRS
ESATHAH

Sequences:

>Translated_407_residues
MKKIALIIGSMIAGGIISAAGFTWFAKAEPPAEKTSTAERKILFWYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSAS
GVRIDPTQTQNLGVKTATVTRGPLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGAPLLDLTIPDWVE
AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKIQG
MDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTLTIRKWTLLPGVDAATRTLQLRLEVDNADEALKPGMNAWLQLNTA
SEPMLLIPSQALIDTGSEQRVITVDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANISGALERMRS
ESATHAH
>Mature_407_residues
MKKIALIIGSMIAGGIISAAGFTWFAKAEPPAEKTSTAERKILFWYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSAS
GVRIDPTQTQNLGVKTATVTRGPLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGAPLLDLTIPDWVE
AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKIQG
MDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTLTIRKWTLLPGVDAATRTLQLRLEVDNADEALKPGMNAWLQLNTA
SEPMLLIPSQALIDTGSEQRVITVDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANISGALERMRS
ESATHAH

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=407, Percent_Identity=99.5085995085995, Blast_Score=821, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 44323; Mature: 44323

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIALIIGSMIAGGIISAAGFTWFAKAEPPAEKTSTAERKILFWYDPMYPNTRFDKPGK
CCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHCCCCCEEEEEEECCCCCCCCCCCCCC
SPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRGPLTFAQSFPANVSYNEYQ
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCCHHHHCCCCCCCCCCEE
YAIVQARAAGFIDKVYPLTVGDKVQKGAPLLDLTIPDWVEAQSEYLLLRETGGTATQTEG
EEEEEEHHHCCHHHEEEEECCCHHHCCCCEEEEECCHHHCCCCCEEEEEECCCCCHHHHH
ILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKIQG
HHHHHHHCCCCHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEHHCCCCCCCCCEEEEEEC
MDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTLTIRKWTLLPGVDAATRTLQLRLEV
CCCEEEEECCHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEEECCCCCCCCEEEEEEEEE
DNADEALKPGMNAWLQLNTASEPMLLIPSQALIDTGSEQRVITVDADGRFVPKRVAVFQA
CCCHHHHCCCCCEEEEEECCCCCEEEECCHHHHCCCCCCEEEEECCCCCCCCCEEEEEEC
SQGVTALRSGLAEGEKVVSSGLFLIDSEANISGALERMRSESATHAH
CCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKIALIIGSMIAGGIISAAGFTWFAKAEPPAEKTSTAERKILFWYDPMYPNTRFDKPGK
CCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHCCCCCEEEEEEECCCCCCCCCCCCCC
SPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRGPLTFAQSFPANVSYNEYQ
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCCHHHHCCCCCCCCCCEE
YAIVQARAAGFIDKVYPLTVGDKVQKGAPLLDLTIPDWVEAQSEYLLLRETGGTATQTEG
EEEEEEHHHCCHHHEEEEECCCHHHCCCCEEEEECCHHHCCCCCEEEEEECCCCCHHHHH
ILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKIQG
HHHHHHHCCCCHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEHHCCCCCCCCCEEEEEEC
MDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTLTIRKWTLLPGVDAATRTLQLRLEV
CCCEEEEECCHHHHHHHHCCCCEEEEEECCCCCCEEEEEEEEECCCCCCCCEEEEEEEEE
DNADEALKPGMNAWLQLNTASEPMLLIPSQALIDTGSEQRVITVDADGRFVPKRVAVFQA
CCCHHHHCCCCCEEEEEECCCCCEEEECCHHHHCCCCCCEEEEECCCCCCCCCEEEEEEC
SQGVTALRSGLAEGEKVVSSGLFLIDSEANISGALERMRSESATHAH
CCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]