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The map label for this gene is yfcJ

Identifier: 209400286

GI number: 209400286

Start: 3206747

End: 3207925

Strand: Reverse

Name: yfcJ

Synonym: ECH74115_3462

Alternate gene names: 209400286

Gene position: 3207925-3206747 (Counterclockwise)

Preceding gene: 209399153

Following gene: 209395784

Centisome position: 57.57

GC content: 56.57

Gene sequence:

>1179_bases
ATGACTGCTGTAAGCCAAACCGAAACACGATCTTCTGCCAATTTTTCGCTCTTCCGCATCGCTTTTGCGGTTTTTCTCAC
CTACATGACCGTAGGGTTGCCGTTGCCGGTTATCCCGTTGTTTGTTCATCATGATCTGGGCTATGGCAATACCATGGTCG
GCATTGCCGTCGGCATTCAGTTTCTGGCTACGGTGCTGACGCGTGGCTATGCCGGGCGACTGGCCGATCAATATGGCGCA
AAACGTTCGGCGCTTCAGGGGATGTTAGCTTGTGGTCTGGCTGGCGGCGCGTTGCTGCTGGCGGCGATTTTGCCTGTCTC
CGCACCGTTCAAATTTGCCCTGTTGGTCATCGGGCGTTTGATTCTTGGGTTTGGTGAAAGCCAGTTACTGACAGGCGCTC
TGACCTGGGGGTTAGGCATCGTAGGGCCAAAACACTCTGGCAAAGTGATGTCATGGAATGGAATGGCGATTTACGGTGCC
CTCGCTGTTGGTGCTCCGCTTGGCCTGTTGATTCATAGCCATTACGGTTTTGCCGCACTGGCGCTCACCACAATGGCATT
ACCCTTACTGGCGTGGGCCTGTAACGGCACAGTGCGCAAAGTACCAGCCCTGGCGGGAGAACGTCCATCTCTGTGGAGCG
TTGTCGGACTTATCTGGAAACCAGGGTTAGGTCTGGCACTACAAGGCGTTGGTTTTGCGGTTATCGGGACTTTCGTTTCG
CTCTACTTTGCCAGCAAAGGATGGGCGATGGCGGGCTTTACTCTTACCGCGTTTGGCGGCGCATTTGTCGTGATGCGCGT
CATGTTTGGCTGGATGCCGGACCGTTTTGGCGGCGTGAAAGTGGCGATTGTCTCTCTGCTTGTAGAAACGGTGGGCTTGT
TGCTGCTCTGGCAAGCCCCAGGGGCGTGGGTCGCATTAGCGGGCGCGGCGTTAACCGGAGCCGGATGTTCGCTTATCTTT
CCTGCGCTGGGTGTGGAGGTGGTTAAACGCGTCCCCTCACAAGTTCGCGGCACCGCACTGGGCGGTTACGCCGCGTTTCA
GGATATCGCCCTCGGCGTCTCCGGGCCGCTTGCGGGAATGCTGGCGACCACGTTTGGTTACTCTTCGGTATTTCTTGCCG
GGGCGATCTCTGCGGTGCTGGGAATTATTGTCACGATACTGTCGTTTCGTCGGGGTTAA

Upstream 100 bases:

>100_bases
AAAGACGTACGCGTTAAATCCTGCCAACGCACTGTAACCCTGAAACCAGAGAGATGAGACGGGGATACTCCTCGCCTTGC
GCTGCATTCTGGAGTAATGC

Downstream 100 bases:

>100_bases
CGAACCAGCCAGACCAGCATCAGGATAATCGCGACTAACAGTATCCACAGCGCGGGACGCGTTGCCATATTTTGCAACGT
GTCCATCATCGGTGGAAAAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHHDLGYGNTMVGIAVGIQFLATVLTRGYAGRLADQYGA
KRSALQGMLACGLAGGALLLAAILPVSAPFKFALLVIGRLILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGA
LAVGAPLGLLIHSHYGFAALALTTMALPLLAWACNGTVRKVPALAGERPSLWSVVGLIWKPGLGLALQGVGFAVIGTFVS
LYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRFGGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGAGCSLIF
PALGVEVVKRVPSQVRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGIIVTILSFRRG

Sequences:

>Translated_392_residues
MTAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHHDLGYGNTMVGIAVGIQFLATVLTRGYAGRLADQYGA
KRSALQGMLACGLAGGALLLAAILPVSAPFKFALLVIGRLILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGA
LAVGAPLGLLIHSHYGFAALALTTMALPLLAWACNGTVRKVPALAGERPSLWSVVGLIWKPGLGLALQGVGFAVIGTFVS
LYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRFGGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGAGCSLIF
PALGVEVVKRVPSQVRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGIIVTILSFRRG
>Mature_391_residues
TAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHHDLGYGNTMVGIAVGIQFLATVLTRGYAGRLADQYGAK
RSALQGMLACGLAGGALLLAAILPVSAPFKFALLVIGRLILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGAL
AVGAPLGLLIHSHYGFAALALTTMALPLLAWACNGTVRKVPALAGERPSLWSVVGLIWKPGLGLALQGVGFAVIGTFVSL
YFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRFGGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGAGCSLIFP
ALGVEVVKRVPSQVRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGIIVTILSFRRG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0226 family

Homologues:

Organism=Escherichia coli, GI1788662, Length=392, Percent_Identity=98.7244897959184, Blast_Score=748, Evalue=0.0,
Organism=Escherichia coli, GI87082270, Length=365, Percent_Identity=43.013698630137, Blast_Score=254, Evalue=5e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YFCJ_ECO57 (Q8X564)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   F91029
- PIR:   G85873
- RefSeq:   NP_288896.1
- RefSeq:   NP_311233.1
- ProteinModelPortal:   Q8X564
- SMR:   Q8X564
- EnsemblBacteria:   EBESCT00000028163
- EnsemblBacteria:   EBESCT00000060046
- GeneID:   915695
- GeneID:   958147
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3585
- KEGG:   ecs:ECs3206
- GeneTree:   EBGT00050000008826
- HOGENOM:   HBG299639
- OMA:   VSAPIKF
- ProtClustDB:   PRK12382
- BioCyc:   ECOL83334:ECS3206-MONOMER
- HAMAP:   MF_01118
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR023008

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 40452; Mature: 40321

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x409e4354)-; HASH(0xf5d50dc)-; HASH(0x10422258)-; HASH(0x1024e414)-; HASH(0x102ece9c)-; HASH(0xe7c14e8)-; HASH(0x1042224c)-; HASH(0x409f86e8)-; HASH(0x1036cf00)-; HASH(0xfa99a74)-; HASH(0xf7eaef4)-; HASH(0xfd139e4)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHHDLGYGNTMVGIAVGIQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHH
FLATVLTRGYAGRLADQYGAKRSALQGMLACGLAGGALLLAAILPVSAPFKFALLVIGRL
HHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGALAVGAPLGLLIHSHYGFAAL
HHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHCHHHHHHHCCCCHHHH
ALTTMALPLLAWACNGTVRKVPALAGERPSLWSVVGLIWKPGLGLALQGVGFAVIGTFVS
HHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHH
LYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRFGGVKVAIVSLLVETVGLLLLWQAP
HHHHCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEECCC
GAWVALAGAALTGAGCSLIFPALGVEVVKRVPSQVRGTALGGYAAFQDIALGVSGPLAGM
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHCCCCHHHHH
LATTFGYSSVFLAGAISAVLGIIVTILSFRRG
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
TAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHHDLGYGNTMVGIAVGIQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHH
FLATVLTRGYAGRLADQYGAKRSALQGMLACGLAGGALLLAAILPVSAPFKFALLVIGRL
HHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGALAVGAPLGLLIHSHYGFAAL
HHCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHCHHHHHHHCCCCHHHH
ALTTMALPLLAWACNGTVRKVPALAGERPSLWSVVGLIWKPGLGLALQGVGFAVIGTFVS
HHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHHHHH
LYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRFGGVKVAIVSLLVETVGLLLLWQAP
HHHHCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHEEEECCC
GAWVALAGAALTGAGCSLIFPALGVEVVKRVPSQVRGTALGGYAAFQDIALGVSGPLAGM
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHCCCCHHHHH
LATTFGYSSVFLAGAISAVLGIIVTILSFRRG
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796