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The map label for this gene is mhpF [H]

Identifier: 209400221

GI number: 209400221

Start: 435120

End: 436070

Strand: Direct

Name: mhpF [H]

Synonym: ECH74115_0426

Alternate gene names: 209400221

Gene position: 435120-436070 (Clockwise)

Preceding gene: 209399486

Following gene: 209398846

Centisome position: 7.81

GC content: 54.68

Gene sequence:

>951_bases
ATGAGTAAGCGTAAAGTCGCCATTATCGGTTCTGGCAACATTGGCACCGATCTGATGATTAAAATTTTGCGTCACGATCA
GCATCTGGAGATGGCGGTGATGGTCGGCATTGATCCTCAGTCCGACGGTCTGGCGCGTGCCAGACGTATGGGCGTCGCCA
CCACCCATGAAGGGGTGATCGGGCTGATGAACATGCCTGAATTTGCTGATATCGACATTGTATTTGATGCGACCAGCGCC
GGTGCTCATGTGAAAAACGATGCGGCTTTGCGCGAAGCGAAACCGGATATTCGCTTAATTGACCTGACGCCTGCTGCCAT
CGGCCCTTACTGCGTGCCGGTGGTTAACCTCGAGGAGAACGTCGATCAACTGAACGTCAACATGGTCACCTGCGGCGGCC
AGGCCACCATTCCAATGGTGGCGGCAGTTTCACGCGTGGTGCGTGTTCATTACGCCGAAATTATCGCTTCTATCGCCAGT
AAATCTGCCGGACCTGGCACGCGTGCCAATATCGATGAATTTACGGAAACCACTTCGCGAGCCATTGAAGTGGTGGGCGG
CGCGGCAAAAGGGAAGGCGATTATCGTGCTTAACCCAGCAGAGCCACCGTTGATGATGCGTGACACGGTGTATGTATTGA
GCGACGAAGCTTCACAAGATGATATCGAAGCCTCAATCAATGAAATGGCTGAGGCGGTGCAGGCTTACGTACCGGGATAT
CGCCTGAAACAGCGCGTGCAGTTTGAAGTTATCCCGCAGGATAAACCGGTTAATTTGCCGGGCGTAGGGCAGTTCTCCGG
GCTGAAAACGGCGGTCTGGCTGGAAGTCGAAGGCGCAGCGCATTATCTGCCTGCCTATGCGGGCAACCTCGACATTATGA
CTTCCAGTGCGCTGGCGACAGCAGAAAAAATGGCCCAGTCACTGGCGCGCAAGGCAGGAGAAGCGGCATGA

Upstream 100 bases:

>100_bases
TGGTGGCAGTGAATGCGGGCGATCGTTTTGAAGCCCATATTGAAGGCATAGGTTCAGTTGCTGCGGCATTTTCAAGCGCA
GCCCCAAAAGGAAGTCTGTC

Downstream 100 bases:

>100_bases
ACGGTAAAAAACTTTATATCTCGGACGTCACGTTGCGTGACGGTATGCACGCCATTCGTCATCGGTATTCGCTGGAAAAC
GTTCGCCAGATTGCCAAAGC

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating] [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSKRKVAIIGSGNIGTDLMIKILRHDQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSA
GAHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEENVDQLNVNMVTCGGQATIPMVAAVSRVVRVHYAEIIASIAS
KSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGY
RLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA

Sequences:

>Translated_316_residues
MSKRKVAIIGSGNIGTDLMIKILRHDQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSA
GAHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEENVDQLNVNMVTCGGQATIPMVAAVSRVVRVHYAEIIASIAS
KSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGY
RLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA
>Mature_315_residues
SKRKVAIIGSGNIGTDLMIKILRHDQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAG
AHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEENVDQLNVNMVTCGGQATIPMVAAVSRVVRVHYAEIIASIASK
SAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGYR
LKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds [H]

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786547, Length=316, Percent_Identity=99.0506329113924, Blast_Score=636, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.10 [H]

Molecular weight: Translated: 33587; Mature: 33456

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRKVAIIGSGNIGTDLMIKILRHDQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVI
CCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCEE
GLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEEN
EECCCCCCCCEEEEEECCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCC
VDQLNVNMVTCGGQATIPMVAAVSRVVRVHYAEIIASIASKSAGPGTRANIDEFTETTSR
CCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGY
HHHHHCCCCCCCEEEEECCCCCCEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCH
RLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLPAYAGNLDIMTSSALAT
HHHEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHCCCEEEEEHHHHHH
AEKMAQSLARKAGEAA
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKRKVAIIGSGNIGTDLMIKILRHDQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVI
CCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCEE
GLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEEN
EECCCCCCCCEEEEEECCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCC
VDQLNVNMVTCGGQATIPMVAAVSRVVRVHYAEIIASIASKSAGPGTRANIDEFTETTSR
CCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGY
HHHHHCCCCCCCEEEEECCCCCCEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCH
RLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLPAYAGNLDIMTSSALAT
HHHEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHCCCEEEEEHHHHHH
AEKMAQSLARKAGEAA
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA