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The map label for this gene is ylaB [H]

Identifier: 209400088

GI number: 209400088

Start: 546718

End: 548268

Strand: Reverse

Name: ylaB [H]

Synonym: ECH74115_0547

Alternate gene names: 209400088

Gene position: 548268-546718 (Counterclockwise)

Preceding gene: 209399987

Following gene: 209400977

Centisome position: 9.84

GC content: 47.9

Gene sequence:

>1551_bases
GTGAGAACACGACATCTGGTCGGCCTTATTTCGGGAGTACTGATTCTTTCAGTATTGCTGCCTGTCGGCTTAAGCATCTG
GCTGGCCCATCAGCAGGTAGAAACATCGTTTATTGAAGAGCTGGATACCTATTCCTCCCGCGTCGCTATTCGGGCCAATA
AGGTGGCGACACAAGGGAAAGATGCGCTGCAAGAGCTGGAAAGATGGCAAGGCGCTGACTGTAGTGAAGCCCATCTCATG
GAAATGCGTCGGGTATCTTACAGTTATCGCTATATTCAGGAAGTGGTTTATATCGATAACAACGTTCCCCAGTGTTCGTC
TCTGGAGCATGAAAGTCCGCCCGATACCTTCCCCGAGCCAGGTAAAATTTCGAAAGATGGTTATCGTGTCTGGTTAACAT
CACATAACGATTTAGGCATTATCCGTTACATGGTCGCCATGGGAACGGCACATTATGTCGTCATGATCGACCCCGCTTCC
TTTATTGATGTCATTCCCTATAGCTCATGGCAAATTGATGCCGCCATTATTGGCAATGCCCATAACGTTGTCATAACCAG
CAGCGATGAAATTGCTCAGGGAATTATTACCAGGCTACAAAAAACACCCGGTGAGCATATCGAAAATAATGGAATCATTT
ACGATATCCTGCCCTTCCCGGAGATGAATATTTCAATTATCACCTGGGCTTCATCGAAAATGTTGCAGAAAGGCTGGCAT
CGGCAAGTCTTTATTTGGTTACCGCTCGGGTTGGTGATTGGCCTGCTGGCAGCGATGTTTGTGCTGCGCATTTTGCGCCG
CATCCAGTCACCGCATCATCGGCTGCAGGATGCTATCGAAAATCGTGATATTTGCGTGCACTATCAGCCGATTGTCTCCT
TAGCCAATGGCAAAATTGTCGGTGCTGAGGCACTGGCGCGCTGGCCGCAGACAGACGGTAGTTGGTTGTCACCAGATAGT
TTTATTCCGCTGGCACAGCAAACGGGCCTTTCTGAGCCATTGACGCTACTGATTATAAGAAGCGTCTTTGAAGATATGGG
CGACTGGCTGCGTCAGCATCCACAGCAGCATATTTCGATCAATCTTGAATCCACCGTGCTCACCTCGGAAAAAATCCCGC
AATTGCTGCGTGAAATGATCAATCACTATCAGGTTAATCCCAGACAGATCGCGCTTGAACTCACTGAACGCGAGTTTGCC
GATCCGAAAACCAGCGCCCCGATAATTTCTCGCTACCGGGAGGCGGGCCATGAAATTTATCTTGATGATTTTGGTACGGG
GTATTCAAGTTTAAGTTATTTACAGGATCTGGATGTCGACATTCTGAAGATCGATAAATCTTTCGTTGATGCGCTGGAAT
ATAAAAATGTCACGCCGCATATCATCGAAATGGCAAAAACACTGAAACTGAAAATGGTAGCGGAGGGAATCGAAACCAGT
AAACAAGAAGAGTGGCTACGCCAGCATGGCGTGCACTACGGTCAGGGCTGGCTCTACAGCAAGGCATTACCGAAAGAAGA
TTTCTTACGCTGGGCCGAGCAACATTTGTGA

Upstream 100 bases:

>100_bases
CATCACTTCATGAAATACCAGCTCTACCTCCTTATCTCCTGCCAGCCTTTTTCCACAATCAGATATACTTTCCCTACACT
GTGTTAATAAGGATATGCTG

Downstream 100 bases:

>100_bases
ATTTTTGGGCTGACGGCACGCCGCACAGCCCGTCACGCTACCTATTCGTCGATGATTGACTCGAATCCGCCATAGATCAT
TCGCTTGCCGTCAAACGGCA

Product: cyclic diguanylate phosphodiesterase (EAL) domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQGKDALQELERWQGADCSEAHLM
EMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
FIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPFPEMNISIITWASSKMLQKGWH
RQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDS
FIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIALELTEREFA
DPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETS
KQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL

Sequences:

>Translated_516_residues
MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQGKDALQELERWQGADCSEAHLM
EMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
FIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPFPEMNISIITWASSKMLQKGWH
RQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDS
FIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIALELTEREFA
DPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETS
KQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL
>Mature_516_residues
MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQGKDALQELERWQGADCSEAHLM
EMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
FIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPFPEMNISIITWASSKMLQKGWH
RQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDS
FIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIALELTEREFA
DPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETS
KQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL

Specific function: Unknown

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI87081743, Length=516, Percent_Identity=98.8372093023256, Blast_Score=1050, Evalue=0.0,
Organism=Escherichia coli, GI1790496, Length=528, Percent_Identity=33.7121212121212, Blast_Score=298, Evalue=4e-82,
Organism=Escherichia coli, GI87081845, Length=293, Percent_Identity=34.4709897610922, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI226510982, Length=237, Percent_Identity=35.8649789029536, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1788502, Length=270, Percent_Identity=31.4814814814815, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1787541, Length=247, Percent_Identity=30.3643724696356, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI87081980, Length=236, Percent_Identity=36.4406779661017, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786507, Length=245, Percent_Identity=33.0612244897959, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1788849, Length=263, Percent_Identity=30.4182509505703, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI87081921, Length=245, Percent_Identity=33.469387755102, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87082096, Length=242, Percent_Identity=30.9917355371901, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1787055, Length=241, Percent_Identity=26.9709543568465, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58831; Mature: 58831

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHCCH
DALQELERWQGADCSEAHLMEMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFPEP
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPASFIDVIPYSSWQIDAAIIGNA
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCEEEEEEECCC
HNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPFPEMNISIITWASSKMLQKGWH
CEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEEECCHHHHHCCCC
RQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIV
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEHHHHHHCCCCEE
GAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHISI
CHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEE
NLESTVLTSEKIPQLLREMINHYQVNPRQIALELTEREFADPKTSAPIISRYREAGHEIY
EEHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEHHHHCCCCCCCCHHHHHHHHCCCEEE
LDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETS
EECCCCCHHHHHHHHHCCCHHEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
KQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL
HHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQGK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHCCH
DALQELERWQGADCSEAHLMEMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFPEP
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
GKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPASFIDVIPYSSWQIDAAIIGNA
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCHHHHHHCCCCCCEEEEEEECCC
HNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPFPEMNISIITWASSKMLQKGWH
CEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEEECCHHHHHCCCC
RQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIV
CEEEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEHHHHHHCCCCEE
GAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHISI
CHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHEEE
NLESTVLTSEKIPQLLREMINHYQVNPRQIALELTEREFADPKTSAPIISRYREAGHEIY
EEHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEEHHHHCCCCCCCCHHHHHHHHCCCEEE
LDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETS
EECCCCCHHHHHHHHHCCCHHEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
KQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL
HHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]