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The map label for this gene is fepG [H]

Identifier: 209400073

GI number: 209400073

Start: 705127

End: 706119

Strand: Reverse

Name: fepG [H]

Synonym: ECH74115_0674

Alternate gene names: 209400073

Gene position: 706119-705127 (Counterclockwise)

Preceding gene: 209399652

Following gene: 209399490

Centisome position: 12.67

GC content: 57.4

Gene sequence:

>993_bases
ATGATTTACGTCTCTCGCCGATTACTCATCACCTGTTTGCTGCTGATTTCCGCCTGTGTGGTTGCAGGTATCTGGGGATT
ACGCAGCGGTGCCGTCACGCTGGAAATCTCGCAGGTATTCGCCGCGCTGATGGGCGATGCGCCGCGCAGTATGACGATGG
TGGTCACCGAATGGCGTTTACCACGCGTGCTGATGGCGCTGTTGATTGGCGCGGCACTGGGCGTCAGCGGTGCGATTTTT
CAGTCGCTGATGCGTAACCCACTCGGCAGCCCTGACGTAATGGGCTTTAACACCGGGGCGTGGAGCGGCGTGTTGGTGGC
GATGGTGCTGTTTGGTCAGGATCTGACGGCTATCGCGCTGGCAGCAATGGTGGGCGGCATTATCACTTCGCTGTTGGTCT
GGCTGCTCGCCTGGCGTAACGGTATCGACACCTTTCGGTTGATTATTATCGGTATCGGCGTTCGCGCCATGCTGGTGGCC
TTTAATACCTGGCTGTTGCTGAAAGCGTCTTTAGAAACGGCGCTAACAGCAGGTTTGTGGAATGCCGGATCGCTCAACGG
CCTGACGTGGGCAAAAACCTCGCCTTCCGCACCCATCATTATATTGATGCTAATTGCCGCCGCCTTACTGGTACGCCGGA
TGCGCTTGCTGGAAATGGGCGATGATACCGCGTGTGCGCTGGGCGTCAGCGTCGAACGTTCGCGTCTGTTAATGATGCTG
GTTGCAGTGGTGCTTACCGCTGCGGCAACAGCGCTTGCCGGGCCGATTTCCTTTATTGCTTTAGTCGCGCCGCACATTGC
CCGACGCATTAGCGGCACCGCTCGCTGGGGGCTAACCCAGGCGGCGCTATGCGGGGCGCTGTTACTGCTGGCGGCCGATC
TCTGCGCCCAACAACTGTTTATGCCGTATCAACTTCCGGTTGGCGTCGTTACCGTCAGCCTCGGCGGTATTTACCTTATC
GTTTTGTTAATTCAGGAGTCTCGCAAAAAATGA

Upstream 100 bases:

>100_bases
GGGTGATTGTGCCCGGTGAACTGCGCGTTTCTGTGGTCAGTGCGTTTATTGGTGCACCGGTGCTGATCTTCCTCGTGCGA
CGTAAAACGCGAGGTGGTGC

Downstream 100 bases:

>100_bases
CCGAATCAGTAGCCCGTTTGCGCGGCGAACAGTTAACCCTGGGATATGGCAAATATACCGTTGCGGAAAATCTGACTGTA
GAAATACCTGATGGTCACTT

Product: iron-enterobactin transporter permease

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MIYVSRRLLITCLLLISACVVAGIWGLRSGAVTLEISQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF
QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMVGGIITSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI
VLLIQESRKK

Sequences:

>Translated_330_residues
MIYVSRRLLITCLLLISACVVAGIWGLRSGAVTLEISQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF
QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMVGGIITSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI
VLLIQESRKK
>Mature_330_residues
MIYVSRRLLITCLLLISACVVAGIWGLRSGAVTLEISQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF
QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMVGGIITSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI
VLLIQESRKK

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4779

COG function: function code P; ABC-type enterobactin transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=330, Percent_Identity=98.7878787878788, Blast_Score=631, Evalue=0.0,
Organism=Escherichia coli, GI1790740, Length=288, Percent_Identity=37.8472222222222, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786347, Length=277, Percent_Identity=35.3790613718412, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786805, Length=309, Percent_Identity=36.5695792880259, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790741, Length=280, Percent_Identity=33.5714285714286, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1788004, Length=294, Percent_Identity=35.0340136054422, Blast_Score=99, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34935; Mature: 34935

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYVSRRLLITCLLLISACVVAGIWGLRSGAVTLEISQVFAALMGDAPRSMTMVVTEWRL
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEHHHH
PRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIAL
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
AAMVGGIITSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETALTAGLW
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHH
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHC
MPYQLPVGVVTVSLGGIYLIVLLIQESRKK
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIYVSRRLLITCLLLISACVVAGIWGLRSGAVTLEISQVFAALMGDAPRSMTMVVTEWRL
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCEEEEEHHHH
PRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIAL
HHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
AAMVGGIITSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETALTAGLW
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHH
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHC
MPYQLPVGVVTVSLGGIYLIVLLIQESRKK
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 9278503 [H]