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The map label for this gene is cdh

Identifier: 209400064

GI number: 209400064

Start: 5013002

End: 5013757

Strand: Direct

Name: cdh

Synonym: ECH74115_5373

Alternate gene names: 209400064

Gene position: 5013002-5013757 (Clockwise)

Preceding gene: 209400686

Following gene: 209399380

Centisome position: 89.97

GC content: 48.81

Gene sequence:

>756_bases
ATGAAAAAAGCGGGTCTTCTTTTTTTGGTGATGATAGTTATCGCCGTTGTGGCTGCCGGTATTGGTTACTGGAAATTAAC
CGGTGAAGAGTCGGATACATTACGTAAGATTGTCCTTGAGGAATGTTTGCCCAATCAGCAGCAAAATCAAAATCCTTCGC
CATGTGCGGAAGTCAAACCCAATGCCGGATACGTGGTTTTAAAAGATCTTAATGGCCCACTGCAATATCTGTTGATGCCA
ACGTATCGTATTAACGGTACTGAAAGTCCTTTGTTGACCGATCCTTCAACGCCGAACTTCTTTTGGTTGGCCTGGCAGGC
GCGTGATTTTATGAGCAAAAAATACGGCCAGCCGGTTCCCGATCGCGCGGTTTCTTTGGCGATCAACTCCCGCACCGGGC
GTACGCAAAACCATTTTCATATTCATATCTCTTGTATTCGTCCTGATGTGCGCGAACAGCTGGATAACAATCTGGCGAAC
ATCAGCAGCCGCTGGTTGCCACTGCCAGGTGGTTTGCGCGGGCATGAATACCTGGCGCGTCGGGTAACGGAAAGCGAACT
GGTACAACGCAGCCCATTTATGATGCTGGCAGAAGAAGTACCTGAGGCGCGGGAACATATGGGAAGCTACGGGCTGGCGA
TGGTACGGCAGAGTGATAACTCATTTGTATTGCTGGCGACACAACGAAATCTACTGACGCTTAACCGTGCTTCAGCCGAG
GAAATTCAGGATCATCAGTGTGAGATTTTGCGTTAA

Upstream 100 bases:

>100_bases
CAGGATAATTATCAAACCCGGTGGTTTCTCGCGACCGGGTTTTTTATTTGTCACGATTTTGCGTTACCCTTGCATCTCTT
TGAGGTACAGGGAAAAAAAG

Downstream 100 bases:

>100_bases
GGCGAAGAGTTAAGGAAAGTAAGTGCCGGATATGAAATCCGGCACCTGTCAGACTTAAGCCTGTTTAGCCGCTTCTGCAG
CTTTAACGATTACTGCGAAA

Product: CDP-diacylglycerol pyrophosphatase

Products: NA

Alternate protein names: CDP-diacylglycerol phosphatidylhydrolase; CDP-diglyceride hydrolase

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLPNQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMP
TYRINGTESPLLTDPSTPNFFWLAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLAN
ISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQSDNSFVLLATQRNLLTLNRASAE
EIQDHQCEILR

Sequences:

>Translated_251_residues
MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLPNQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMP
TYRINGTESPLLTDPSTPNFFWLAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLAN
ISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQSDNSFVLLATQRNLLTLNRASAE
EIQDHQCEILR
>Mature_251_residues
MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLPNQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMP
TYRINGTESPLLTDPSTPNFFWLAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLAN
ISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQSDNSFVLLATQRNLLTLNRASAE
EIQDHQCEILR

Specific function: Phospholipid biosynthesis. [C]

COG id: COG2134

COG function: function code I; CDP-diacylglycerol pyrophosphatase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cdh family

Homologues:

Organism=Escherichia coli, GI1790352, Length=251, Percent_Identity=99.203187250996, Blast_Score=519, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDH_ECO24 (A7ZUD2)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001465411.1
- ProteinModelPortal:   A7ZUD2
- SMR:   A7ZUD2
- STRING:   A7ZUD2
- EnsemblBacteria:   EBESCT00000023075
- GeneID:   5590584
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_4452
- eggNOG:   COG2134
- GeneTree:   EBGT00050000011118
- HOGENOM:   HBG565233
- OMA:   EIQDHEC
- ProtClustDB:   PRK05471
- BioCyc:   ECOL331111:ECE24377A_4452-MONOMER
- HAMAP:   MF_00319
- InterPro:   IPR003763
- InterPro:   IPR015993
- PIRSF:   PIRSF001273
- TIGRFAMs:   TIGR00672

Pfam domain/function: PF02611 CDH

EC number: =3.6.1.26

Molecular weight: Translated: 28383; Mature: 28383

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x110d676c)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLPNQQQNQNPSPCAEVKP
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
NAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFWLAWQARDFMSKKYGQPVP
CCCEEEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEHHHHHHHHCCCCCC
DRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLANISSRWLPLPGGLRGHEYLAR
CCEEEEEEECCCCCCCCEEEEEEEEECCHHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHH
RVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQSDNSFVLLATQRNLLTLNRASAE
HHCHHHHHHCCCHHHHHHHCHHHHHHHCCCCEEEEEECCCCEEEEEECCCEEEECCCCHH
EIQDHQCEILR
HHHHCHHHCCH
>Mature Secondary Structure
MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLPNQQQNQNPSPCAEVKP
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
NAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFWLAWQARDFMSKKYGQPVP
CCCEEEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEHHHHHHHHCCCCCC
DRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLANISSRWLPLPGGLRGHEYLAR
CCEEEEEEECCCCCCCCEEEEEEEEECCHHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHH
RVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQSDNSFVLLATQRNLLTLNRASAE
HHCHHHHHHCCCHHHHHHHCHHHHHHHCCCCEEEEEECCCCEEEEEECCCEEEECCCCHH
EIQDHQCEILR
HHHHCHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA