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The map label for this gene is yghZ

Identifier: 209399849

GI number: 209399849

Start: 3991336

End: 3992376

Strand: Direct

Name: yghZ

Synonym: ECH74115_4313

Alternate gene names: 209399849

Gene position: 3991336-3992376 (Clockwise)

Preceding gene: 209399743

Following gene: 209399644

Centisome position: 71.63

GC content: 52.07

Gene sequence:

>1041_bases
ATGGTCTGGTTAGCGAATCCCGAACGTTACGGGCAGATGCAATACCGCTATTGCGGAAAAAGCGGTTTACGCCTGCCCGC
GTTATCGCTCGGTTTATGGCACAATTTCGGTCACGTTAACGCGCTGGAATCACAGCGTGCGATCCTGCGTAAAGCGTTTG
ATTTAGGCATTACGCACTTTGATTTAGCCAACAATTACGGGCCGCCTCCAGGAAGCGCAGAAGAGAACTTTGGTCGCCTG
CTGCGGGAGGATTTTGCCGCTTATCGCGATGAACTGATTATCTCTACCAAAGCTGGCTACGATATGTGGCCCGGCCCTTA
CGGCTCTGGCGGTTCACGTAAATACCTGCTCGCCAGCCTCGACCAAAGCCTGAAGCGTATGGGGCTTGAGTATGTCGATA
TCTTTTACTCTCATCGCGTCGATGAAAATACGCCGATGGAAGAAACCGCCTCTGCGCTGGCTCATGCGGTACAAAGCGGT
AAGGCGCTGTATGTCGGGATCTCCTCTTACTCACCAGAGCGGACGCAAAAAATGGTCGAGTTGCTGCACGAGTGGAAAAT
TCCGCTGTTAATTCATCAACCTTCGTACAATTTACTAAACCGCTGGGTGGATAAAAGCGGCCTGCTGGATACCCTGCAAA
ATAACGGCGTGGGCTGCATTGCCTTTACTCCTCTGGCTCAGGGATTGCTGACCGGAAAATATCTCAACGGCATTCCTGAA
GATTCACGGATGCATCGTGAAGGGAATAAAGTTCGTGGTCTGACGCCGAAAATGCTCACCGAAGCCAACCTCAACAGCCT
ACGCTTATTGAATGAAATGGCACAGCAGCGTGGACAATCAATGGCGCAAATGGCGTTAAGCTGGTTGCTGAAAGATGAGC
GAGTGACGTCGGTATTGGTTGGTGCCAGCCGCGCGGAGCAACTTGAGGAGAACGTGCAGGCGCTGAATAATCTGACATTT
AGCACCGAGGAGCTGGCGCAGATCGATCAGCATATCGCCGATGGCGAGCTGAATCTGTGGCAGGCGTCTTCCGATAAATG
A

Upstream 100 bases:

>100_bases
CAGTTTTTCGTCACTCTGTGAGCCAGACTACGGGATACGCGCTGGCGAATCGCTAAACTAGAAACATTGTTTCGAAATTG
AACGGTGGAAAGGAGAGGTC

Downstream 100 bases:

>100_bases
CCTGTTAATAACGGGCGCGAGAACCGCGCCCGAATCAGATCAGTGATTATGACGAGTCAGTCGGTCAAGATAGCCCATTA
CAAATGCAGAGAGCACAAAC

Product: aldo-keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYVGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPE
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDERVTSVLVGASRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK

Sequences:

>Translated_346_residues
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYVGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPE
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDERVTSVLVGASRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK
>Mature_346_residues
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYVGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPE
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDERVTSVLVGASRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27436969, Length=329, Percent_Identity=35.258358662614, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI4504825, Length=338, Percent_Identity=35.5029585798817, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI27436964, Length=324, Percent_Identity=34.8765432098765, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI27436962, Length=324, Percent_Identity=34.8765432098765, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI27436966, Length=324, Percent_Identity=34.5679012345679, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI27436971, Length=326, Percent_Identity=33.7423312883436, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI41152114, Length=212, Percent_Identity=31.6037735849057, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI41327764, Length=214, Percent_Identity=30.3738317757009, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI223718702, Length=286, Percent_Identity=29.3706293706294, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1789375, Length=346, Percent_Identity=98.5549132947977, Blast_Score=707, Evalue=0.0,
Organism=Escherichia coli, GI87081735, Length=330, Percent_Identity=35.7575757575758, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789199, Length=350, Percent_Identity=28.8571428571429, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788070, Length=318, Percent_Identity=26.7295597484277, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788081, Length=323, Percent_Identity=24.1486068111455, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=23.7388724035608, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319958, Length=238, Percent_Identity=25.6302521008403, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323998, Length=315, Percent_Identity=24.7619047619048, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322615, Length=238, Percent_Identity=25.2100840336134, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24640980, Length=345, Percent_Identity=28.4057971014493, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI45549126, Length=345, Percent_Identity=28.4057971014493, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24646159, Length=334, Percent_Identity=24.5508982035928, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24646155, Length=322, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YGHZ_ECO57 (Q8X529)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   E85959
- PIR:   E91114
- RefSeq:   NP_289578.1
- RefSeq:   NP_311912.1
- ProteinModelPortal:   Q8X529
- SMR:   Q8X529
- EnsemblBacteria:   EBESCT00000024621
- EnsemblBacteria:   EBESCT00000060122
- GeneID:   916499
- GeneID:   958479
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4354
- KEGG:   ecs:ECs3885
- GeneTree:   EBGT00050000009263
- HOGENOM:   HBG605727
- OMA:   GSLKQEH
- ProtClustDB:   PRK09912
- BioCyc:   ECOL83334:ECS3885-MONOMER
- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210
- Gene3D:   G3DSA:3.20.20.100
- PANTHER:   PTHR11732
- PANTHER:   PTHR11732:SF14

Pfam domain/function: PF00248 Aldo_ket_red; SSF51430 Aldo/ket_red

EC number: NA

Molecular weight: Translated: 38816; Mature: 38816

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHF
CEECCCHHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEE
DLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASL
EHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHH
DQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSGKALYVGISSYSPERTQKMVE
HHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
LLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPE
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCC
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDERVTSVLV
HHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GASRAEQLEENVQALNNLTFSTEELAQIDQHIADGELNLWQASSDK
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHF
CEECCCHHHHCCHHHHHHCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEE
DLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASL
EHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHH
DQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSGKALYVGISSYSPERTQKMVE
HHHHHHHCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
LLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPE
HHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCC
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDERVTSVLV
HHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GASRAEQLEENVQALNNLTFSTEELAQIDQHIADGELNLWQASSDK
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796