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The map label for this gene is tatC

Identifier: 209399791

GI number: 209399791

Start: 4922160

End: 4922936

Strand: Direct

Name: tatC

Synonym: ECH74115_5279

Alternate gene names: 209399791

Gene position: 4922160-4922936 (Clockwise)

Preceding gene: 209400771

Following gene: 209397688

Centisome position: 88.34

GC content: 51.74

Gene sequence:

>777_bases
ATGTCTGTAGAAGATACTCAACCGCTTATCACGCATCTGATTGAGCTGCGTAAGCGTCTGCTGAACTGCATTATCGCGGT
GATCGTGATATTCCTGTGTCTGGTCTATTTCGCCAATGACATCTATCACCTGGTATCCGCGCCATTGATCAAGCAGTTGC
CGCAAGGTTCAACGATGATCGCCACCGACGTGGCCTCGCCGTTCTTTACGCCGATCAAGCTGACCTTTATGGTGTCGCTG
ATTCTGTCAGCGCCGGTGATTCTCTATCAGGTGTGGGCATTTATCGCCCCAGCGCTGTATAAGCATGAACGTCGCCTGGT
GGTGCCGCTGCTGGTTTCCAGCTCTCTGCTATTTTATATCGGCATGGCGTTCGCCTACTTTGTGGTCTTTCCGCTGGCAT
TTGGCTTCCTTGCCAATACCGCGCCGGAAGGGGTGCAGGTATCCACCGACATCGCCAGCTATTTAAGCTTCGTTATGGCG
CTGTTTATGGCGTTTGGTGTCTCCTTTGAAGTGCCGGTGGCAATTGTGCTGCTGTGCTGGATGGGGATTACCTCGCCAGA
AGACTTACGCAAAAAACGCCCGTATGTGCTGGTTGGTGCATTCGTTGTCGGGATGTTGCTGACGCCGCCGGATGTCTTCT
CGCAAACGCTGTTGGCGATCCCGATGTACTGTCTGTTTGAAATCGGTGTCTTCTTCTCACGCTTTTACGTTGGTAAAGGG
CGAAATCGGGAAGAGGAAAACGACGCTGAAGCAGAAAGCGAAAAAACTGAAGAATAA

Upstream 100 bases:

>100_bases
AGAAGCCAGAAACCACGCCAGAGCCGGTGGTAAAACCTGCTGCGGACGCTGAACCGAAAACCGCTGCACCTTCCCCTTCG
TCGAGTGATAAACCGTAAAC

Downstream 100 bases:

>100_bases
ATTCAACCGCCCGTCAGGGCGGTTGTCATATGGAGTACAGGATGTTTGATATCGGCGTTAATTTGACCAGTTCGCAATTT
GCGAAAGACCGTGATGATGT

Product: twin-arginine protein translocation system subunit TatC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSVEDTQPLITHLIELRKRLLNCIIAVIVIFLCLVYFANDIYHLVSAPLIKQLPQGSTMIATDVASPFFTPIKLTFMVSL
ILSAPVILYQVWAFIAPALYKHERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMA
LFMAFGVSFEVPVAIVLLCWMGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLLAIPMYCLFEIGVFFSRFYVGKG
RNREEENDAEAESEKTEE

Sequences:

>Translated_258_residues
MSVEDTQPLITHLIELRKRLLNCIIAVIVIFLCLVYFANDIYHLVSAPLIKQLPQGSTMIATDVASPFFTPIKLTFMVSL
ILSAPVILYQVWAFIAPALYKHERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMA
LFMAFGVSFEVPVAIVLLCWMGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLLAIPMYCLFEIGVFFSRFYVGKG
RNREEENDAEAESEKTEE
>Mature_257_residues
SVEDTQPLITHLIELRKRLLNCIIAVIVIFLCLVYFANDIYHLVSAPLIKQLPQGSTMIATDVASPFFTPIKLTFMVSLI
LSAPVILYQVWAFIAPALYKHERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMAL
FMAFGVSFEVPVAIVLLCWMGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLLAIPMYCLFEIGVFFSRFYVGKGR
NREEENDAEAESEKTEE

Specific function: Required for correct localization of precursor proteins bearing signal peptides with the twin arginine conserved motif S/T-R-R-X-F-L-K. This sec-independent pathway is termed TAT for twin-arginine translocation system. This system mainly transports protei

COG id: COG0805

COG function: function code U; Sec-independent protein secretion pathway component TatC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatC family

Homologues:

Organism=Escherichia coli, GI2367313, Length=258, Percent_Identity=100, Blast_Score=521, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TATC_ECO57 (P69424)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   F86071
- PIR:   H91224
- RefSeq:   NP_290470.1
- RefSeq:   NP_312795.1
- ProteinModelPortal:   P69424
- EnsemblBacteria:   EBESCT00000028885
- EnsemblBacteria:   EBESCT00000058046
- GeneID:   915136
- GeneID:   960320
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z5360
- KEGG:   ecs:ECs4768
- GeneTree:   EBGT00050000010074
- HOGENOM:   HBG733232
- OMA:   TDINNYL
- ProtClustDB:   PRK10921
- BioCyc:   ECOL83334:ECS4768-MONOMER
- InterPro:   IPR002033
- InterPro:   IPR019820
- InterPro:   IPR019822
- PRINTS:   PR01840
- TIGRFAMs:   TIGR00945

Pfam domain/function: PF00902 TatC

EC number: NA

Molecular weight: Translated: 28877; Mature: 28745

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS01218 TATC

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x12af9234)-; HASH(0x129f32c4)-; HASH(0x12d10100)-; HASH(0x130269ec)-; HASH(0x119c1a24)-; HASH(0x12fea68c)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEDTQPLITHLIELRKRLLNCIIAVIVIFLCLVYFANDIYHLVSAPLIKQLPQGSTMI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
ATDVASPFFTPIKLTFMVSLILSAPVILYQVWAFIAPALYKHERRLVVPLLVSSSLLFYI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMALFMAFGVSFEVPVAIVLLCW
HHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLLAIPMYCLFEIGVFFSRFYVGKG
HCCCCHHHHHHCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RNREEENDAEAESEKTEE
CCCCCCHHHHHHHCCCCH
>Mature Secondary Structure 
SVEDTQPLITHLIELRKRLLNCIIAVIVIFLCLVYFANDIYHLVSAPLIKQLPQGSTMI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
ATDVASPFFTPIKLTFMVSLILSAPVILYQVWAFIAPALYKHERRLVVPLLVSSSLLFYI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
GMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMALFMAFGVSFEVPVAIVLLCW
HHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLLAIPMYCLFEIGVFFSRFYVGKG
HCCCCHHHHHHCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RNREEENDAEAESEKTEE
CCCCCCHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796