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The map label for this gene is yeeO [H]

Identifier: 209399760

GI number: 209399760

Start: 2635299

End: 2636753

Strand: Reverse

Name: yeeO [H]

Synonym: ECH74115_2829

Alternate gene names: 209399760

Gene position: 2636753-2635299 (Counterclockwise)

Preceding gene: 209396344

Following gene: 209396736

Centisome position: 47.32

GC content: 49.55

Gene sequence:

>1455_bases
TTGAATATCTCCTCTGCTTTACGCCAGGTTGTTCACGGCACTCGCTGGCACGCTAAACGCAAGAGCTACAAAGTGTTGTT
CTGGCGCGAGATAACCCCGTTTGCTGTTCCTATCTTCATGGAGAATGCCTGTGTCCTGTTGATGGGGGTTCTGAGCACTT
TTCTGGTCAGCTGGCTGGGAAAAGATGCGATGGCCGGCGTGGGATTGGCGGACAGCTTCAATATGGTCATTATGGCTTTT
TTTGCTGCTATCGATCTTGGTACTACTGTCGTTGTGGCATTTAGTCTCGGTAAGCGGGATCGACGACGAGCGAGGGTGGC
GACGCGGCAGTCATTGGTGATCATGACGTTGTTTGCCGTACTGTTGGCAACGCTTATTCATCATTTTGGCGAGCAAATTA
TTGATTTCGTCGCGGGTGATGCCACGACAGAAGTTAAAGCACTGGCGTTGACTTATCTGGAGCTGACGGTACTCAGTTAT
CCAGCAGCTGCCATCACTCTAATTGGTAGCGGGGCACTTCGTGGTGCAGGGAATACGAAAATACCGCTACTGATTAACGG
TAGCCTGAATATTCTTAATATTATTATTAGCGGCATATTGATTTACGGCCTTTTCTCCTGGCCGGGACTGGGATTTGTCG
GGGCTGGGTTGGGTTTAACCATTTCTCGTTATATTGGCGCAGTTGCAATTTTGTGGGTGCTGGCGATTGGTTTTAATCCT
GCGCTAAGGATTTCGTTAAAGAGCTATTTTAAACCGCTGAATTTTAGCATTATCTGGGAAGTCATGGGGATTGGTATTCC
AGCGAGTGTCGAATCAGTGTTATTTACCAGTGGTCGGTTATTAACCCAAATGTTCGTTGCCGGAATGGGGACCAGTGTTA
TTGCCGGAAATTTTATCGCGTTTTCAATTGCGGCTCTTATCAACTTACCCGGAAGTGCGCTCGGTTCTGCTTCTACGATC
ATTACAGGCCGAAGGTTGGGGGTAGGGCAGATAGCGCAAGCAGAGATTCAGTTGCGGCATGTGTTTTGGCTGACCACTCT
TGGATTAACGGCCATCGCCTGGCTAACGGCTCCCTTTGCCGGGGTTATGGCATCGTTTTACACCCAGGATCCACAGGTTA
AACATGTCGTTGTGATTCTGATTTGGCTAAATGCTTTATTTATGCCTATTTGGTCCGCTTCATGGGTGCTACCCGCTGGA
TTTAAGGGGGCTCGTGACGCCCGTTACGCTATGTGGGTTTCTATGTTGAGCATGTGGGGTTGTCGGGTTGTCGTCGGTTA
TGTGCTGGGCATCATGCTTGGCTGGGGTGTGGTTGGTGTCTGGATGGGAATGTTTGCCGACTGGGCTGTGCGGGCCGTGC
TGTTTTACTGGCGAATGGTTACTGGACGTTGGCTGTGGAAATACCCTCGACCCGAACCGCAAAAGTGTGAAAAAAAGCCA
GCTGTGTCGGAATAA

Upstream 100 bases:

>100_bases
TTGCATTTGCAGACAATTTGATGGCGAAAATCTTTGCAGCTTTGCTGATTCTCCCTCATTATTTGAAATGTGGTTTCACT
TTCTGCAATTAAGGTCGGCT

Downstream 100 bases:

>100_bases
ACGACAAAATGCAGATTATTTCAGCAAACGATTTCAAATTTAAAAAACAGGCTTTGACATTGTGGGTGGGCATCGCTAAT
ATTCGCCTCGTTCTCACGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MNISSALRQVVHGTRWHAKRKSYKVLFWREITPFAVPIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAF
FAAIDLGTTVVVAFSLGKRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVKALALTYLELTVLSY
PAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSWPGLGFVGAGLGLTISRYIGAVAILWVLAIGFNP
ALRISLKSYFKPLNFSIIWEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTI
ITGRRLGVGQIAQAEIQLRHVFWLTTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILIWLNALFMPIWSASWVLPAG
FKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVGVWMGMFADWAVRAVLFYWRMVTGRWLWKYPRPEPQKCEKKP
AVSE

Sequences:

>Translated_484_residues
MNISSALRQVVHGTRWHAKRKSYKVLFWREITPFAVPIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAF
FAAIDLGTTVVVAFSLGKRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVKALALTYLELTVLSY
PAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSWPGLGFVGAGLGLTISRYIGAVAILWVLAIGFNP
ALRISLKSYFKPLNFSIIWEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTI
ITGRRLGVGQIAQAEIQLRHVFWLTTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILIWLNALFMPIWSASWVLPAG
FKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVGVWMGMFADWAVRAVLFYWRMVTGRWLWKYPRPEPQKCEKKP
AVSE
>Mature_484_residues
MNISSALRQVVHGTRWHAKRKSYKVLFWREITPFAVPIFMENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAF
FAAIDLGTTVVVAFSLGKRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVKALALTYLELTVLSY
PAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSWPGLGFVGAGLGLTISRYIGAVAILWVLAIGFNP
ALRISLKSYFKPLNFSIIWEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTI
ITGRRLGVGQIAQAEIQLRHVFWLTTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILIWLNALFMPIWSASWVLPAG
FKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVGVWMGMFADWAVRAVLFYWRMVTGRWLWKYPRPEPQKCEKKP
AVSE

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=484, Percent_Identity=99.1735537190083, Blast_Score=954, Evalue=0.0,
Organism=Escherichia coli, GI48994890, Length=455, Percent_Identity=23.0769230769231, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 52820; Mature: 52820

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISSALRQVVHGTRWHAKRKSYKVLFWREITPFAVPIFMENACVLLMGVLSTFLVSWLG
CCHHHHHHHHHHCHHHHHCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHC
KDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARVATRQSLVIMTLFAV
CHHHCCCCCCCHHHHHHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LLATLIHHFGEQIIDFVAGDATTEVKALALTYLELTVLSYPAAAITLIGSGALRGAGNTK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHEECCCCCCCCCCCE
IPLLINGSLNILNIIISGILIYGLFSWPGLGFVGAGLGLTISRYIGAVAILWVLAIGFNP
EEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
ALRISLKSYFKPLNFSIIWEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIA
CEEEEHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHH
FSIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLTTLGLTAIAWLTAPFA
HHHHHHHHCCCCCCCCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVMASFYTQDPQVKHVVVILIWLNALFMPIWSASWVLPAGFKGARDARYAMWVSMLSMWG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHH
CRVVVGYVLGIMLGWGVVGVWMGMFADWAVRAVLFYWRMVTGRWLWKYPRPEPQKCEKKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHHHCCCC
AVSE
CCCC
>Mature Secondary Structure
MNISSALRQVVHGTRWHAKRKSYKVLFWREITPFAVPIFMENACVLLMGVLSTFLVSWLG
CCHHHHHHHHHHCHHHHHCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHC
KDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLGKRDRRRARVATRQSLVIMTLFAV
CHHHCCCCCCCHHHHHHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
LLATLIHHFGEQIIDFVAGDATTEVKALALTYLELTVLSYPAAAITLIGSGALRGAGNTK
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHEECCCCCCCCCCCE
IPLLINGSLNILNIIISGILIYGLFSWPGLGFVGAGLGLTISRYIGAVAILWVLAIGFNP
EEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
ALRISLKSYFKPLNFSIIWEVMGIGIPASVESVLFTSGRLLTQMFVAGMGTSVIAGNFIA
CEEEEHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHH
FSIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQLRHVFWLTTLGLTAIAWLTAPFA
HHHHHHHHCCCCCCCCCHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVMASFYTQDPQVKHVVVILIWLNALFMPIWSASWVLPAGFKGARDARYAMWVSMLSMWG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHH
CRVVVGYVLGIMLGWGVVGVWMGMFADWAVRAVLFYWRMVTGRWLWKYPRPEPQKCEKKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCHHHCCCC
AVSE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]