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The map label for this gene is sapC [H]

Identifier: 209399657

GI number: 209399657

Start: 1828576

End: 1829466

Strand: Reverse

Name: sapC [H]

Synonym: ECH74115_1933

Alternate gene names: 209399657

Gene position: 1829466-1828576 (Counterclockwise)

Preceding gene: 209400983

Following gene: 209400028

Centisome position: 32.83

GC content: 57.24

Gene sequence:

>891_bases
ATGCCTTACGATAGCGTATACAGCGAAAAGCGCCCGCCGGGCACGCTGCGTACCGCCTGGCGCAAATTTTATAGTGACGC
CTCTGCGATGGTCGGCCTGTACGGCTGCGCGGGGCTGGCTGTACTGTGTATGTTTGGCGGCTGGTTTGCGCCTTACGGCA
TCGACCAGCAATTTCTCGGTTACCAATTATTGCCGCCATCATGGTCGCGCTATGGCGAAGTTTCTTTCTTCCTGGGGACT
GACGACCTCGGACGCGATGTTTTAAGCCGTTTACTGAGCGGAGCTGCGCCAACCGTGGGTGGCGCATTTGTGGTGACACT
TGCCGCGACGATCTGTGGCCTGGTACTGGGCACCTTCGCCGGGGCGACGCACGGCCTCCGCTCAGCGGTGCTTAACCATA
TTCTGGATACCTTACTGGCGATCCCTTCCCTGCTGTTGGCAATTATCGTTGTAGCGTTTGCCGGACCGAGTTTGTCCCAC
GCTATGTTTGCTGTCTGGCTGGCGCTGCTGCCGCGTATGGTACGTTCGATTTACAGCATGGTGCATGACGAACTGGAAAA
AGAGTACGTTATCGCCGCCCGTCTGGATGGCGCATCAACGCTGAATATTCTCTGGTTTGCTGTGATGCCTAACATCACCG
CCGGGCTGGTCACCGAGATCACCCGCGCACTGTCGATGGCAATTCTCGATATCGCCGCGCTGGGCTTTCTCGATCTTGGC
GCACAACTCCCCTCGCCTGAATGGGGAGCGATGCTCGGTGATGCGCTGGAACTGATTTATGTCGCCCCGTGGACTGTCAT
GCTGCCAGGTGCGGCAATTATGATTAGCGTGCTGTTGGTTAACCTCCTTGGCGACGGTGTCCGTCGTGCAATTATTGCGG
GGGTGGAATAA

Upstream 100 bases:

>100_bases
TCCGCCGGAGTGATGGTGTGTGGCTCACTGGTCATTATTGTTAACGTGATTTCTGATATTTTGGGTGCCATGGCTAACCC
TCTGAAACATAAGGAATGGT

Downstream 100 bases:

>100_bases
TGCCATTACTCGATATTCGTAACCTGACTATTGAATTTAAAACCGGTGATGAGTGGGTTAAAGCCGTTGACCGGGTAAGT
ATGACCTTAACCGAAGGTGA

Product: peptide ABC transporter, permease protein SapC

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MPYDSVYSEKRPPGTLRTAWRKFYSDASAMVGLYGCAGLAVLCMFGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGT
DDLGRDVLSRLLSGAAPTVGGAFVVTLAATICGLVLGTFAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLSH
AMFAVWLALLPRMVRSIYSMVHDELEKEYVIAARLDGASTLNILWFAVMPNITAGLVTEITRALSMAILDIAALGFLDLG
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMISVLLVNLLGDGVRRAIIAGVE

Sequences:

>Translated_296_residues
MPYDSVYSEKRPPGTLRTAWRKFYSDASAMVGLYGCAGLAVLCMFGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGT
DDLGRDVLSRLLSGAAPTVGGAFVVTLAATICGLVLGTFAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLSH
AMFAVWLALLPRMVRSIYSMVHDELEKEYVIAARLDGASTLNILWFAVMPNITAGLVTEITRALSMAILDIAALGFLDLG
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMISVLLVNLLGDGVRRAIIAGVE
>Mature_295_residues
PYDSVYSEKRPPGTLRTAWRKFYSDASAMVGLYGCAGLAVLCMFGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTD
DLGRDVLSRLLSGAAPTVGGAFVVTLAATICGLVLGTFAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLSHA
MFAVWLALLPRMVRSIYSMVHDELEKEYVIAARLDGASTLNILWFAVMPNITAGLVTEITRALSMAILDIAALGFLDLGA
QLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMISVLLVNLLGDGVRRAIIAGVE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=296, Percent_Identity=99.6621621621622, Blast_Score=584, Evalue=1e-168,
Organism=Escherichia coli, GI1789964, Length=288, Percent_Identity=40.625, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1787054, Length=284, Percent_Identity=34.8591549295775, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1787760, Length=248, Percent_Identity=34.6774193548387, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789889, Length=241, Percent_Identity=30.2904564315353, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787498, Length=275, Percent_Identity=25.4545454545455, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 31567; Mature: 31435

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYDSVYSEKRPPGTLRTAWRKFYSDASAMVGLYGCAGLAVLCMFGGWFAPYGIDQQFLG
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCC
YQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLAATICGLVLGTFA
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLSHAMFAVWLALLPRMVRSIYSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VHDELEKEYVIAARLDGASTLNILWFAVMPNITAGLVTEITRALSMAILDIAALGFLDLG
HHHHHHHHEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMISVLLVNLLGDGVRRAIIAGVE
CCCCCCHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PYDSVYSEKRPPGTLRTAWRKFYSDASAMVGLYGCAGLAVLCMFGGWFAPYGIDQQFLG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCC
YQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLAATICGLVLGTFA
CCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLSHAMFAVWLALLPRMVRSIYSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
VHDELEKEYVIAARLDGASTLNILWFAVMPNITAGLVTEITRALSMAILDIAALGFLDLG
HHHHHHHHEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMISVLLVNLLGDGVRRAIIAGVE
CCCCCCHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]