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The map label for this gene is oppC

Identifier: 209399648

GI number: 209399648

Start: 1668177

End: 1669082

Strand: Direct

Name: oppC

Synonym: ECH74115_1731

Alternate gene names: 209399648

Gene position: 1668177-1669082 (Clockwise)

Preceding gene: 209398544

Following gene: 209397436

Centisome position: 29.94

GC content: 52.54

Gene sequence:

>906_bases
ATGTTAAGTAAGAAAAACAGCGAGACGCTGGAAAATTTCAGTGAAAAGCTGGAGGTCGAAGGGCGCAGCTTGTGGCAGGA
CGCACGTCGACGTTTTATGCATAACCGTGCGGCGGTTGCAAGTCTGATAGTGCTGGTGCTGATCGCGTTATTTGTAATCC
TGGCACCGATGCTTTCGCAGTTTGCCTATGACGATACTGACTGGGCGATGATGTCCAGCGCCCCGGATATGGAGTCCGGT
CACTACTTTGGTACTGACTCATCCGGTCGCGACCTGCTTGTGCGCGTTGCGATTGGCGGACGTATCTCACTCATGGTCGG
TGTTGCTGCGGCACTGGTGGCAGTGGTCGTGGGGACACTTTATGGTTCGCTTTCCGGTTATCTGGGCGGTAAAGTGGATT
CGGTAATGATGCGTTTGCTGGAAATCCTCAACTCCTTCCCATTCATGTTCTTCGTCATTTTGCTGGTGACCTTTTTCGGT
CAAAACATCCTGCTGATTTTCGTGGCGATAGGCATGGTTTCCTGGCTGGATATGGCTCGTATTGTGCGTGGGCAAACCCT
GAGTCTGAAGCGCAAAGAGTTTATTGAGGCGGCACAAGTTGGCGGTGTATCGACGTCGGGCATTGTTATTCGCCACATTG
TGCCGAACGTACTCGGTGTGGTGGTGGTCTACGCATCGCTACTGGTGCCCAGCATGATCCTCTTTGAATCTTTCCTTAGC
TTCCTGGGGTTGGGTACGCAAGAGCCGTTAAGCAGCTGGGGGGCATTGCTGAGTGATGGCGCGAACTCAATGGAAGTCTC
TCCATGGTTACTGTTGTTCCCAGCGGGATTCCTCGTGGTGACGCTGTTTTGTTTCAACTTTATCGGCGATGGCTTGCGTG
ATGCCCTCGACCCGAAAGATCGTTAA

Upstream 100 bases:

>100_bases
TCCTGGTTGGTGCGTTAACCATTTTGTTTAATGCCATTGTCGATGTGCTATATGCGGTTATCGACCCGAAAATCCGTTAC
TGATACTGGAGCTCGCGATG

Downstream 100 bases:

>100_bases
GGAGTGCAGCCATGAGCGTAATTGAAACTGCAACTGTGCCGCTCGCACAACAACAGGCTGACGCACTGCTGAACGTGAAA
GATTTGCGTGTCACCTTTAG

Product: oligopeptide ABC transporter, permease protein OppC

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MLSKKNSETLENFSEKLEVEGRSLWQDARRRFMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDTDWAMMSSAPDMESG
HYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFG
QNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTSGIVIRHIVPNVLGVVVVYASLLVPSMILFESFLS
FLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKDR

Sequences:

>Translated_301_residues
MLSKKNSETLENFSEKLEVEGRSLWQDARRRFMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDTDWAMMSSAPDMESG
HYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFG
QNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTSGIVIRHIVPNVLGVVVVYASLLVPSMILFESFLS
FLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKDR
>Mature_301_residues
MLSKKNSETLENFSEKLEVEGRSLWQDARRRFMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDTDWAMMSSAPDMESG
HYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFG
QNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTSGIVIRHIVPNVLGVVVVYASLLVPSMILFESFLS
FLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKDR

Specific function: Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1787498, Length=301, Percent_Identity=100, Blast_Score=597, Evalue=1e-172,
Organism=Escherichia coli, GI1787054, Length=279, Percent_Identity=36.5591397849462, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI1787760, Length=261, Percent_Identity=35.2490421455939, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1789889, Length=226, Percent_Identity=31.4159292035398, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788505, Length=251, Percent_Identity=32.2709163346614, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1789964, Length=278, Percent_Identity=32.3741007194245, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787549, Length=275, Percent_Identity=25.8181818181818, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OPPC_ECO57 (P0AFH7)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A99847
- PIR:   H85704
- RefSeq:   NP_287488.1
- RefSeq:   NP_309772.1
- ProteinModelPortal:   P0AFH7
- EnsemblBacteria:   EBESCT00000023926
- EnsemblBacteria:   EBESCT00000057323
- GeneID:   913106
- GeneID:   960495
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z2021
- KEGG:   ecs:ECs1745
- GeneTree:   EBGT00050000010100
- HOGENOM:   HBG729429
- OMA:   YDDTDWY
- ProtClustDB:   PRK15406
- BioCyc:   ECOL83334:ECS1745-MONOMER
- InterPro:   IPR000515

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 32891; Mature: 32891

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1ff4d1d8)-; HASH(0x1dcfa904)-; HASH(0x1fe58870)-; HASH(0x2035db74)-; HASH(0x1ffe7364)-; HASH(0x201d9750)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKKNSETLENFSEKLEVEGRSLWQDARRRFMHNRAAVASLIVLVLIALFVILAPMLSQ
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAYDDTDWAMMSSAPDMESGHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTL
HCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
YGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMAR
HHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IVRGQTLSLKRKEFIEAAQVGGVSTSGIVIRHIVPNVLGVVVVYASLLVPSMILFESFLS
HHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKD
HHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
R
H
>Mature Secondary Structure
MLSKKNSETLENFSEKLEVEGRSLWQDARRRFMHNRAAVASLIVLVLIALFVILAPMLSQ
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAYDDTDWAMMSSAPDMESGHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTL
HCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
YGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMAR
HHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IVRGQTLSLKRKEFIEAAQVGGVSTSGIVIRHIVPNVLGVVVVYASLLVPSMILFESFLS
HHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKD
HHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
R
H

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796