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The map label for this gene is pssA [H]

Identifier: 209399593

GI number: 209399593

Start: 3547041

End: 3548396

Strand: Direct

Name: pssA [H]

Synonym: ECH74115_3822

Alternate gene names: 209399593

Gene position: 3547041-3548396 (Clockwise)

Preceding gene: 209400567

Following gene: 209397756

Centisome position: 63.66

GC content: 48.82

Gene sequence:

>1356_bases
ATGTTGTCAAAATTTAAGCGTAATAAACATCAACAACACCTTGCCCAACTACCCAAGATTTCTCAATCAGTTGATGATGT
CGATTTCTTTTACGCTCCCGCCGACTTCCGGGAGACGCTGCTGGAAAAAATAGCCAGCGCGAAGCAGCGCATTTGCATTG
TCGCCCTGTATCTCGAACAGGATGACGGTGGCAAAGGCATTCTGAACGCGTTGTATGAAGCTAAAAGGCAGCGTCCGGAA
CTGGATGTGCGGGTGCTGCTCGACTGGCATCGTGCACAACGTGGACGCATTGGCGCTGCGGCATCTAACACTAACGCTGA
CTGGTACTGTCGCATGGCGCAGGAAAATCCGGGCGTAGATGTTCCGGTTTATGGCGTTCCAATCAATACCCGTGAAGCCC
TTGGTGTTCTGCACTTTAAAGGCTTTATCATCGACGATAGCGTACTTTATAGCGGTGCCAGCCTGAACGATGTTTACCTG
CATCAGCACGATAAATATCGCTACGACCGTTATCATCTTATCCGTAACCGTAAGATGTCAGACATTATGTTTGAATGGGT
TACACAGAATATTATGAATGGCCGCGGCGTTAATCGTCTGGATGATGTTAATCGGCCAAAAAGCCCGGAAATCAAGAACG
ATATTCGTCTGTTCCGCCAGGAGCTGCGTGATGCCGCTTATCATTTCCAGGGCGATGCCGACAACGATCAGCTTTCCGTA
ACGCCGCTAGTGGGGCTGGGGAAATCGAGTCTGTTGAACAAGACCATTTTCCATCTTATGCCTTGTGCCGAGCAGAAACT
AACCATCTGTACGCCATACTTCAACCTGCCAGCAATCCTTGTGCGCAATATTATCCAGTTGCTGCGCGAAGGGAAAAAGG
TCGAAATTATTGTTGGTGATAAAACCGCGAACGACTTCTACATTCCGGAAGATGAACCTTTCAAGATAATTGGCGCATTG
CCTTATCTCTATGAGATCAATCTGCGTCGTTTCCTGAGCCGTTTGCAGTATTACGTCAATACTGACCAGCTAGTGGTTCG
GTTATGGAAAGATGACGACAACACCTATCACCTAAAAGGGATGTGGGTTGATGATAAGTGGATGTTGATCACCGGTAATA
ACCTGAACCCGCGCGCCTGGCGTCTGGATCTGGAAAACGCCATTTTGATCCACGATCCACAACTGGAGCTTGCGCCGCAG
CGAGAGAAAGAACTGGAGCTGATCCGCGAGCATACCACCATCGTTAAGCACTATCGCGATCTGCAAAGTATTGCCGATTA
TCCGGTGAAGGTTCGTAAACTCATCCGCCGTTTGCGCCGTATCCGCATCGACCGATTAATTAGCCGCATCCTGTAA

Upstream 100 bases:

>100_bases
AATGTTGACCACTTAATCGGGACTGGTGTTATTATTGCACGCTTATGTCGTCTGCATTGCACAGAGGACCCTTCAATGAA
CAGAGAAGAAATGCACTGTG

Downstream 100 bases:

>100_bases
TCACAACCCCGTCCTGTACGGGGTTTGTTTTTTGGAGGCCACGTTTTGCGTATTCTTTTTGTCTGTTCGCTATTGTTACT
TTCTGGATGCAGCCATATGG

Product: phosphatidylserine synthase

Products: NA

Alternate protein names: Phosphatidylserine synthase [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKIASAKQRICIVALYLEQDDGGKGILNALYEAKRQRPE
LDVRVLLDWHRAQRGRIGAAASNTNADWYCRMAQENPGVDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
HQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLFRQELRDAAYHFQGDADNDQLSV
TPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNLPAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGAL
PYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLITGNNLNPRAWRLDLENAILIHDPQLELAPQ
REKELELIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRIL

Sequences:

>Translated_451_residues
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKIASAKQRICIVALYLEQDDGGKGILNALYEAKRQRPE
LDVRVLLDWHRAQRGRIGAAASNTNADWYCRMAQENPGVDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
HQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLFRQELRDAAYHFQGDADNDQLSV
TPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNLPAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGAL
PYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLITGNNLNPRAWRLDLENAILIHDPQLELAPQ
REKELELIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRIL
>Mature_451_residues
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKIASAKQRICIVALYLEQDDGGKGILNALYEAKRQRPE
LDVRVLLDWHRAQRGRIGAAASNTNADWYCRMAQENPGVDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
HQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLFRQELRDAAYHFQGDADNDQLSV
TPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNLPAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGAL
PYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLITGNNLNPRAWRLDLENAILIHDPQLELAPQ
REKELELIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRIL

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI87082134, Length=451, Percent_Identity=99.7782705099778, Blast_Score=926, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25143331, Length=461, Percent_Identity=26.2472885032538, Blast_Score=98, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6319842, Length=343, Percent_Identity=25.0728862973761, Blast_Score=73, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016270
- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: =2.7.8.8 [H]

Molecular weight: Translated: 52817; Mature: 52817

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKIASAKQRICIVALYLEQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCEEEEEEEEEC
DDGGKGILNALYEAKRQRPELDVRVLLDWHRAQRGRIGAAASNTNADWYCRMAQENPGVD
CCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCC
VPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYLHQHDKYRYDRYHLIRNRKMS
CEEEECCCCCHHHHEEEEEEEEEEECHHHCCCCCCCEEEEECCCCCCHHHHHHHHCCCHH
DIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLFRQELRDAAYHFQGDADNDQLSV
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
TPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNLPAILVRNIIQLLREGKKVEIIVGD
EEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECC
KTANDFYIPEDEPFKIIGALPYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKG
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEE
MWVDDKWMLITGNNLNPRAWRLDLENAILIHDPQLELAPQREKELELIREHTTIVKHYRD
EEECCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LQSIADYPVKVRKLIRRLRRIRIDRLISRIL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKIASAKQRICIVALYLEQ
CCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHCCCEEEEEEEEEC
DDGGKGILNALYEAKRQRPELDVRVLLDWHRAQRGRIGAAASNTNADWYCRMAQENPGVD
CCCCHHHHHHHHHHHHCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCC
VPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYLHQHDKYRYDRYHLIRNRKMS
CEEEECCCCCHHHHEEEEEEEEEEECHHHCCCCCCCEEEEECCCCCCHHHHHHHHCCCHH
DIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLFRQELRDAAYHFQGDADNDQLSV
HHHHHHHHHHHHCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
TPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNLPAILVRNIIQLLREGKKVEIIVGD
EEEECCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECC
KTANDFYIPEDEPFKIIGALPYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKG
CCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEE
MWVDDKWMLITGNNLNPRAWRLDLENAILIHDPQLELAPQREKELELIREHTTIVKHYRD
EEECCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LQSIADYPVKVRKLIRRLRRIRIDRLISRIL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2002065; 9205837; 9278503; 1323044 [H]