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The map label for this gene is ydcR [H]

Identifier: 209399584

GI number: 209399584

Start: 1940357

End: 1941763

Strand: Direct

Name: ydcR [H]

Synonym: ECH74115_2044

Alternate gene names: 209399584

Gene position: 1940357-1941763 (Clockwise)

Preceding gene: 209398671

Following gene: 209397208

Centisome position: 34.82

GC content: 51.67

Gene sequence:

>1407_bases
ATGAAAAAATACCAGCAGCTTGCAGAACAATTACGCGAGCAGATTGCGTCGGGTATCTGGCAACCCGGCGATCGTTTACC
TTCGTTGCGTGACCAGGTGGCGCTTTCTGGCATGAGCTTTATGACTGTCAGCCATGCCTATCAGTTGCTCGAAAGTCAGG
GATATATTATCGCACGACCGCAGTCGGGTTATTACGTTGCGCCACAGGCAATAAAAATGCCGAAAGTGCCAGTCATTCCA
GTCACTCGAGATGAAGCAGTCGATATCAACACTTATATTTTTGATATGTTGCAGGCCAGTCGCGATCCGTCGGTCGTTCC
GTTTGCCTCGGCCTTTCCCGACCCGCGACTTTTCCCCCTCCAACAACTAAACCGCTCGCTGGCGCAGGTAAGCAAAACCG
CCACGGCGATGAGCGTGATTGAAAACTTGCCGCCAGGAAACGCAGAACTGCGTCAGGCTATTGCCCGTCGCTATGCCTTA
CAGGGGATCACCATTTCTCCTGATGAAATTGTCATCACTGCCGGGGCGTTAGAGGCATTAAACCTCAGTTTGCAAGCGGT
AACTGAACCGGGCGATTGGGTGATAGTAGAGAATCCTTGTTTCTACGGTGCGTTGCAGGCGCTGGAGCGGCTACGGCTGA
AGGCGTTATCGGTGGCGACGGATGTTAAAGAAGGGATCGATCTTCAGGCGCTGGAACTGGCGTTGCAGGAGTATCCGGTG
AAAGCGTGCTGGCTGATGACTAATAGCCAGAATCCACTCGGATTTACCTTAACGCCGCAAAAAAAAGCACAACTGGTGGC
GTTGCTCAATCAGTACAACGTAACGCTGATTGAAGATGACGTTTACAGCGAACTTTATTTTGGACGGGAAAAACCGCTGC
CTGCGAAAGCGTGGGATCGCCACGATGGCGTTTTGCATTGCTCTTCGTTTTCGAAATGTCTGGTGCCTGGTTTTCGTATT
GGTTGGGTCGCCGCCGGAAAACATGCACGTAAAATTCAACGCTTGCAGCTGATGAGTACGCTTTCCACCAGCTCACCGAT
GCAGCTTGCGCTGGTGGATTACCTTTCCACGCGCCGATACGACGCCCATCTTCGTCGCCTGCGTCGCCAGCTTGCGGAAC
GTAAACAACGTGCCTGGCAGGCACTGCTGCGTTATCTGCCTGCGGAAGTGAAAATTCATCATAATGACAGCGGTTATTTT
CTCTGGCTGGAGCTCCCCGAGCCGTTAGATGCCGGCGAATTGAGCCTGGCGGCACTGACGCATCATATCAGTATTGCGCC
AGGTAAAATGTTTTCTACCGGTGAAAACTGGTCACGTTTTTTTCGTTTTAATACCGCGTGGCTGTGGGGAGAACGTGAAG
AACAGGCGGTAAAACAATTAGGCAAACTTATTCAAGAACGGCTGTAA

Upstream 100 bases:

>100_bases
GTTATCGCTGGTGATGGTTTAATTACAGTTAACGAAAAGTTGTCATTTTTAACAACTGATATAGACTGCCGAATCATCTG
CACATAATTACGATTCGATA

Downstream 100 bases:

>100_bases
TAGCGTTTAATTTAATTCCTCTTAGATTGGGTAATATGAATTTCGAATAGCAGTCATATTTCCTAACTCCTTGTCTATAC
TCCAGAAGATAACCTTACAG

Product: transcriptional regulator, GntR family/aminotransferase, classes I and II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSGYYVAPQAIKMPKVPVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQEYPV
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRI
GWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYF
LWLELPEPLDAGELSLAALTHHISIAPGKMFSTGENWSRFFRFNTAWLWGEREEQAVKQLGKLIQERL

Sequences:

>Translated_468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSGYYVAPQAIKMPKVPVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQEYPV
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRI
GWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYF
LWLELPEPLDAGELSLAALTHHISIAPGKMFSTGENWSRFFRFNTAWLWGEREEQAVKQLGKLIQERL
>Mature_468_residues
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSGYYVAPQAIKMPKVPVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQEYPV
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRI
GWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYF
LWLELPEPLDAGELSLAALTHHISIAPGKMFSTGENWSRFFRFNTAWLWGEREEQAVKQLGKLIQERL

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=401, Percent_Identity=25.6857855361596, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI33469970, Length=401, Percent_Identity=25.6857855361596, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4507369, Length=236, Percent_Identity=24.1525423728814, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI56713256, Length=397, Percent_Identity=23.4256926952141, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI56713254, Length=397, Percent_Identity=23.4256926952141, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1787710, Length=468, Percent_Identity=99.5726495726496, Blast_Score=957, Evalue=0.0,
Organism=Escherichia coli, GI1790797, Length=466, Percent_Identity=34.9785407725322, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1788722, Length=312, Percent_Identity=26.2820512820513, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17567663, Length=184, Percent_Identity=26.0869565217391, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356535, Length=331, Percent_Identity=24.4712990936556, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI18859735, Length=224, Percent_Identity=28.125, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52807; Mature: 52807

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARP
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECC
QSGYYVAPQAIKMPKVPVIPVTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPL
CCCEEECCHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEHHCCCCCCCCCH
QQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYALQGITISPDEIVITAGALEAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCHHHH
NLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQEYPV
CCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDR
EEEEEEECCCCCCEEEECCHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCCCCCCCC
HDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRY
CCCEEEECCCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYFLWLELPEPLDAGELSLAALT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHH
HHISIAPGKMFSTGENWSRFFRFNTAWLWGEREEQAVKQLGKLIQERL
HHEEECCCCCCCCCCCHHHHEEEEEEEEECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARP
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECC
QSGYYVAPQAIKMPKVPVIPVTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPL
CCCEEECCHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEHHCCCCCCCCCH
QQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYALQGITISPDEIVITAGALEAL
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCHHHH
NLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQEYPV
CCEEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDR
EEEEEEECCCCCCEEEECCHHHHHHHHHHHHCCEEEEECHHHHHHHCCCCCCCCCCCCCC
HDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRY
CCCEEEECCCCHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
DAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYFLWLELPEPLDAGELSLAALT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCCHHHHHHH
HHISIAPGKMFSTGENWSRFFRFNTAWLWGEREEQAVKQLGKLIQERL
HHEEECCCCCCCCCCCHHHHEEEEEEEEECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]