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The map label for this gene is fitA [H]

Identifier: 209399265

GI number: 209399265

Start: 4020476

End: 4022617

Strand: Direct

Name: fitA [H]

Synonym: ECH74115_4343

Alternate gene names: 209399265

Gene position: 4020476-4022617 (Clockwise)

Preceding gene: 209400805

Following gene: 209400811

Centisome position: 72.15

GC content: 48.18

Gene sequence:

>2142_bases
ATGGCTAAGTTCACACCTTCATTCTCAGGAATCAAAGGTCGGGCGCTCTTTTCACTGCTCTTTGCAGCACCAATGATTCA
TGCAACCGACACTGCAACGACCAAAGATGGCGAAACAATCACTGTTACAGCGGATGCAAATACCGCAACTGAGGCGACCG
ATGGTTATCAACCTCTGAGCACTTCCACGGCGACATTAACCGATATGCCGATGCTGGATATCCCGCAGGTGGTCAATACG
GTTAGCGATCAGGTTCTGGAAAATCAGAATGCAACGACGCTGGATGAAGCGCTTTATAACGTCAGTAACGTGGTACAGAC
CAATACATTAGGCGGAACTCAGGACGCCTTTGTACGTCGTGGTTTTGGTGCTAACCGGGATGGCTCCATCATGACCAACG
GCCTGCGAACTGTACTTCCTCGCAGTTTCAACGCCGCCACAGAACGTGTGGAAGTGCTAAAAGGTCCGGCCTCCACGCTG
TATGGCATTCTCGATCCTGGTGGATTGATTAACGTCGTGACCAAGCGCCCGGAAAAAACATTCCATGGTTCTGTCTCAGC
CACGTCCTCCAGTTTTGGCGGAGGCACTGGGCAACTTGATATCACAGGTCCCATTGAAGGCACTCAGCTGGCATACCGCC
TGACGGGGGAAGTGCAGGATGAAGATTACTGGCGAAACTTCGGTAAAGAGCGCAGTACATTTATTGCCCCGTCACTCACC
TGGTTTGGTGATAATGCAACAGTAACCATGCTCTATTCCCATCGGGACTATAAAACTCCGTTCGATCGTGGAACGATTTT
CGACCTTACGACGAAACAGCCCGTAAACGTTGATCGAAAAATACGTTTTGACGAACCGTTTAATATTACAGATGGTCAGT
CCGATCTGGCGCAACTCAACGCAGAATATCATCTCAATAGCCAGTGGACAGCGCGCTTTGATTACAGCTACAGCCAGGAT
AAATACAGCGACAATCAGGCTCGCGTTACCGCGTATGATGCAACGACAGGAACGCTGACACGGCGTGTTGATGCAACTCA
GGGATCTACCCAGCGTATGCATTCTACTCGTGCGGATCTGCAAGGGAATGTTGATATTGCTGGGTTCTATAATGAGATTC
TGGGTGGGGTGTCATATGAATATTATGATCTTCTGCGCACAGATATGATTCGCTGTAAAAACGCTAAAGATTTCAATATC
TACAACCCCGTTTATGGCAATACCAGCAAATGCACAACGGTTTCGGCGTCGGACAGTGATCAGACGATCAAACAGGAGAG
CTACTCAGCTTATGCACAGGATGCGCTCTATCTGACCGATAACTGGATTGCCGTCGCCGGGATCCGCTATCAGTATTACA
CGCAGTATGCGGGTAAAGGCCGTCCTTTTAATGTCAATACTGACAGCCGCGATGAACAATGGACGCCCAAACTGGGGTTA
GTCTACAAACTGACGCCATCGGTATCCTTATTTGCTAATTATTCGCAAACATTTATGCCGCAATCGTCAATTGCCAGCTA
CATCGGAGATCTTCCACCGGAATCATCTAATGCTTACGAAGTCGGGGCAAAATTCGAGCTGTTCGATGGTATAACCGCAG
ATATTGCGCTGTTTGATATCCATAAACGTAACGTGTTGTATACCGAAAGTATTGGTGATGAAACCATCGCCAAAACGGCA
GGCCGCGTTCGTTCAAGAGGGGTAGAAGTCGACCTTGCGGGAGCATTAACTGAAAACATTAATATCATTGCCAGCTACGG
CTATACCGATGCTAAGGTTCTGGAAGATCCTGATTATGCAGGGAAACCATTGCCGAATGTTCCTCGTCATACCGGTTCGC
TATTCCTGACCTATGACATTCATAACATGCCAGGCAATAACACACTGACGTTTGGCGGTGGTGGACATGGCGTAAGCCGT
CGTTCGGCAACCAATGGGGCTGACTATTATCTGCCAGGCTATTTCGTTGCCGATGCCTTCGCCGCATACAAAATGAAATT
GCAGTATCCGGTCACACTGCAATTAAACGTCAAAAACCTGTTTGATAAAACGTATTACACCTCTTCCATCGCCACAAATA
ATCTGGGGAATCAGATTGGCGATCCGCGTGAAGTGCAATTCACGGTGAAAATGGAATTTTGA

Upstream 100 bases:

>100_bases
ACATATCCGATGGTAAAATAACAAACGGATAGTGCTTAGTGAGCAACAAGAAACAATTTTCACTCACGACAATCCGTGAG
TTTTTGGGATAACAGACTAA

Downstream 100 bases:

>100_bases
TCAAAAAAGCCCGGTATACACTTGTATACCGGGCTATGTTTTATTCTTCTGGCGGGAGGATTATCAGACCTCAATCTCCG
CCATGTCGCCTTTCTCTTGC

Product: TonB-dependent outer membrane ferric coprogen receptor FitA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 713; Mature: 712

Protein sequence:

>713_residues
MAKFTPSFSGIKGRALFSLLFAAPMIHATDTATTKDGETITVTADANTATEATDGYQPLSTSTATLTDMPMLDIPQVVNT
VSDQVLENQNATTLDEALYNVSNVVQTNTLGGTQDAFVRRGFGANRDGSIMTNGLRTVLPRSFNAATERVEVLKGPASTL
YGILDPGGLINVVTKRPEKTFHGSVSATSSSFGGGTGQLDITGPIEGTQLAYRLTGEVQDEDYWRNFGKERSTFIAPSLT
WFGDNATVTMLYSHRDYKTPFDRGTIFDLTTKQPVNVDRKIRFDEPFNITDGQSDLAQLNAEYHLNSQWTARFDYSYSQD
KYSDNQARVTAYDATTGTLTRRVDATQGSTQRMHSTRADLQGNVDIAGFYNEILGGVSYEYYDLLRTDMIRCKNAKDFNI
YNPVYGNTSKCTTVSASDSDQTIKQESYSAYAQDALYLTDNWIAVAGIRYQYYTQYAGKGRPFNVNTDSRDEQWTPKLGL
VYKLTPSVSLFANYSQTFMPQSSIASYIGDLPPESSNAYEVGAKFELFDGITADIALFDIHKRNVLYTESIGDETIAKTA
GRVRSRGVEVDLAGALTENINIIASYGYTDAKVLEDPDYAGKPLPNVPRHTGSLFLTYDIHNMPGNNTLTFGGGGHGVSR
RSATNGADYYLPGYFVADAFAAYKMKLQYPVTLQLNVKNLFDKTYYTSSIATNNLGNQIGDPREVQFTVKMEF

Sequences:

>Translated_713_residues
MAKFTPSFSGIKGRALFSLLFAAPMIHATDTATTKDGETITVTADANTATEATDGYQPLSTSTATLTDMPMLDIPQVVNT
VSDQVLENQNATTLDEALYNVSNVVQTNTLGGTQDAFVRRGFGANRDGSIMTNGLRTVLPRSFNAATERVEVLKGPASTL
YGILDPGGLINVVTKRPEKTFHGSVSATSSSFGGGTGQLDITGPIEGTQLAYRLTGEVQDEDYWRNFGKERSTFIAPSLT
WFGDNATVTMLYSHRDYKTPFDRGTIFDLTTKQPVNVDRKIRFDEPFNITDGQSDLAQLNAEYHLNSQWTARFDYSYSQD
KYSDNQARVTAYDATTGTLTRRVDATQGSTQRMHSTRADLQGNVDIAGFYNEILGGVSYEYYDLLRTDMIRCKNAKDFNI
YNPVYGNTSKCTTVSASDSDQTIKQESYSAYAQDALYLTDNWIAVAGIRYQYYTQYAGKGRPFNVNTDSRDEQWTPKLGL
VYKLTPSVSLFANYSQTFMPQSSIASYIGDLPPESSNAYEVGAKFELFDGITADIALFDIHKRNVLYTESIGDETIAKTA
GRVRSRGVEVDLAGALTENINIIASYGYTDAKVLEDPDYAGKPLPNVPRHTGSLFLTYDIHNMPGNNTLTFGGGGHGVSR
RSATNGADYYLPGYFVADAFAAYKMKLQYPVTLQLNVKNLFDKTYYTSSIATNNLGNQIGDPREVQFTVKMEF
>Mature_712_residues
AKFTPSFSGIKGRALFSLLFAAPMIHATDTATTKDGETITVTADANTATEATDGYQPLSTSTATLTDMPMLDIPQVVNTV
SDQVLENQNATTLDEALYNVSNVVQTNTLGGTQDAFVRRGFGANRDGSIMTNGLRTVLPRSFNAATERVEVLKGPASTLY
GILDPGGLINVVTKRPEKTFHGSVSATSSSFGGGTGQLDITGPIEGTQLAYRLTGEVQDEDYWRNFGKERSTFIAPSLTW
FGDNATVTMLYSHRDYKTPFDRGTIFDLTTKQPVNVDRKIRFDEPFNITDGQSDLAQLNAEYHLNSQWTARFDYSYSQDK
YSDNQARVTAYDATTGTLTRRVDATQGSTQRMHSTRADLQGNVDIAGFYNEILGGVSYEYYDLLRTDMIRCKNAKDFNIY
NPVYGNTSKCTTVSASDSDQTIKQESYSAYAQDALYLTDNWIAVAGIRYQYYTQYAGKGRPFNVNTDSRDEQWTPKLGLV
YKLTPSVSLFANYSQTFMPQSSIASYIGDLPPESSNAYEVGAKFELFDGITADIALFDIHKRNVLYTESIGDETIAKTAG
RVRSRGVEVDLAGALTENINIIASYGYTDAKVLEDPDYAGKPLPNVPRHTGSLFLTYDIHNMPGNNTLTFGGGGHGVSRR
SATNGADYYLPGYFVADAFAAYKMKLQYPVTLQLNVKNLFDKTYYTSSIATNNLGNQIGDPREVQFTVKMEF

Specific function: Involved in the initial step of iron uptake by binding chrysobactin, an iron chelatin siderophore that allows the bacteria to extract iron from the environment [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=737, Percent_Identity=27.0013568521031, Blast_Score=161, Evalue=2e-40,
Organism=Escherichia coli, GI1787344, Length=753, Percent_Identity=25.6308100929615, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1790743, Length=323, Percent_Identity=28.4829721362229, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1787024, Length=330, Percent_Identity=26.3636363636364, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 78580; Mature: 78449

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFTPSFSGIKGRALFSLLFAAPMIHATDTATTKDGETITVTADANTATEATDGYQPLS
CCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
TSTATLTDMPMLDIPQVVNTVSDQVLENQNATTLDEALYNVSNVVQTNTLGGTQDAFVRR
CCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEECCCCCCHHHHHHC
GFGANRDGSIMTNGLRTVLPRSFNAATERVEVLKGPASTLYGILDPGGLINVVTKRPEKT
CCCCCCCCCEEECCHHHHCCCCCCHHHHHHHHHCCCHHHEEEEECCCCEEEEEECCCCHH
FHGSVSATSSSFGGGTGQLDITGPIEGTQLAYRLTGEVQDEDYWRNFGKERSTFIAPSLT
HCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCHHHHHCCCCCCEEECCEEE
WFGDNATVTMLYSHRDYKTPFDRGTIFDLTTKQPVNVDRKIRFDEPFNITDGQSDLAQLN
EECCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCEEECCCCCCCCCCHHHHHHCC
AEYHLNSQWTARFDYSYSQDKYSDNQARVTAYDATTGTLTRRVDATQGSTQRMHSTRADL
CEEEECCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHCC
QGNVDIAGFYNEILGGVSYEYYDLLRTDMIRCKNAKDFNIYNPVYGNTSKCTTVSASDSD
CCCEEEEHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCC
QTIKQESYSAYAQDALYLTDNWIAVAGIRYQYYTQYAGKGRPFNVNTDSRDEQWTPKLGL
HHHHHHHHHHHHCCEEEEECCEEEEEEEEEEEEEHHCCCCCCEECCCCCCCCCCCCCCCE
VYKLTPSVSLFANYSQTFMPQSSIASYIGDLPPESSNAYEVGAKFELFDGITADIALFDI
EEEECCCEEEEECCHHHCCCHHHHHHHHCCCCCCCCCCEEECCEEEECCCCEEEEEEEEE
HKRNVLYTESIGDETIAKTAGRVRSRGVEVDLAGALTENINIIASYGYTDAKVLEDPDYA
ECCCEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCEEECCCCCC
GKPLPNVPRHTGSLFLTYDIHNMPGNNTLTFGGGGHGVSRRSATNGADYYLPGYFVADAF
CCCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCEEECCHHHHHHH
AAYKMKLQYPVTLQLNVKNLFDKTYYTSSIATNNLGNQIGDPREVQFTVKMEF
EEEEEEEECCEEEEEEHHHHHHHHEEECHHHCCCCCHHCCCCCEEEEEEEECC
>Mature Secondary Structure 
AKFTPSFSGIKGRALFSLLFAAPMIHATDTATTKDGETITVTADANTATEATDGYQPLS
CCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
TSTATLTDMPMLDIPQVVNTVSDQVLENQNATTLDEALYNVSNVVQTNTLGGTQDAFVRR
CCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEECCCCCCHHHHHHC
GFGANRDGSIMTNGLRTVLPRSFNAATERVEVLKGPASTLYGILDPGGLINVVTKRPEKT
CCCCCCCCCEEECCHHHHCCCCCCHHHHHHHHHCCCHHHEEEEECCCCEEEEEECCCCHH
FHGSVSATSSSFGGGTGQLDITGPIEGTQLAYRLTGEVQDEDYWRNFGKERSTFIAPSLT
HCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCHHHHHCCCCCCEEECCEEE
WFGDNATVTMLYSHRDYKTPFDRGTIFDLTTKQPVNVDRKIRFDEPFNITDGQSDLAQLN
EECCCCEEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCEEECCCCCCCCCCHHHHHHCC
AEYHLNSQWTARFDYSYSQDKYSDNQARVTAYDATTGTLTRRVDATQGSTQRMHSTRADL
CEEEECCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCHHHHHHHHHCC
QGNVDIAGFYNEILGGVSYEYYDLLRTDMIRCKNAKDFNIYNPVYGNTSKCTTVSASDSD
CCCEEEEHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCC
QTIKQESYSAYAQDALYLTDNWIAVAGIRYQYYTQYAGKGRPFNVNTDSRDEQWTPKLGL
HHHHHHHHHHHHCCEEEEECCEEEEEEEEEEEEEHHCCCCCCEECCCCCCCCCCCCCCCE
VYKLTPSVSLFANYSQTFMPQSSIASYIGDLPPESSNAYEVGAKFELFDGITADIALFDI
EEEECCCEEEEECCHHHCCCHHHHHHHHCCCCCCCCCCEEECCEEEECCCCEEEEEEEEE
HKRNVLYTESIGDETIAKTAGRVRSRGVEVDLAGALTENINIIASYGYTDAKVLEDPDYA
ECCCEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCEEECCCCCC
GKPLPNVPRHTGSLFLTYDIHNMPGNNTLTFGGGGHGVSRRSATNGADYYLPGYFVADAF
CCCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCEEECCHHHHHHH
AAYKMKLQYPVTLQLNVKNLFDKTYYTSSIATNNLGNQIGDPREVQFTVKMEF
EEEEEEEECCEEEEEEHHHHHHHHEEECHHHCCCCCHHCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8576065 [H]