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The map label for this gene is rcsA

Identifier: 209399201

GI number: 209399201

Start: 2556125

End: 2556748

Strand: Direct

Name: rcsA

Synonym: ECH74115_2728

Alternate gene names: 209399201

Gene position: 2556125-2556748 (Clockwise)

Preceding gene: 209399396

Following gene: 209396167

Centisome position: 45.87

GC content: 38.3

Gene sequence:

>624_bases
ATGTCAACGATTATTATGGATTTATGTAGTTACACCCGACTAGGTTTAACCGGGTATCTGTTGAGTAGAGGGGTTAAAAA
AAGAGAAATCAACGACATTGAAACCGTTGATGACCTTGCCATAGCTTGTGATTCACAGCGCCCTTCAGTGGTGTTTATTA
ATGAGGACTGTTTCATCCACGATGCTTCTAACAGTCAGCGTATCAAGCTCATCATTAATCAACATCCCAATACGTTATTT
ATCGTTTTTATGGCAATTGCCAATGTTCATTTTGATGAATATCTATTGGTCAGAAAAAATTTATTGATCAGTTCTAAATC
GATTAAACCGGAATCTCTCGACGATATCCTTGGCGATATTCTGAAAAAAGAGACAACGATAACCTCGTTTTTAAATATGC
CGACGTTATCATTGAGCCGAACCGAATCGAGTATGTTGCGAATGTGGATGGCAGGTCAGGGAACCATTCAAATCTCCGAC
CAAATGAATATCAAAGCCAAGACCGTTTCATCGCATAAAGGTAATATTAAACGTAAGATCAAAACGCATAATAAACAGGT
TATCTACCATGTCGTCCGACTGACGGATAATGTGACTAATGGTATTTTTGTCAACATGCGCTAA

Upstream 100 bases:

>100_bases
CGCGAGAGTGGCGCATTAGGTGACCCATGTTGTTCCGTTTAGTCATGATGAAATATTCAGGTAAGGGGAATTATCGTTAC
GCATTGAGTGAGGGTATGCC

Downstream 100 bases:

>100_bases
CACATTCTGACTGGTGGTTTCCCACCAGTCAGGCTGAATTAGATTACTCTGCTTTCTCCACAAAGATACCGTCCTGATGC
CCTGCTTCATTAAAGAACCA

Product: colanic acid capsular biosynthesis activation protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSTIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACDSQRPSVVFINEDCFIHDASNSQRIKLIINQHPNTLF
IVFMAIANVHFDEYLLVRKNLLISSKSIKPESLDDILGDILKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISD
QMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR

Sequences:

>Translated_207_residues
MSTIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACDSQRPSVVFINEDCFIHDASNSQRIKLIINQHPNTLF
IVFMAIANVHFDEYLLVRKNLLISSKSIKPESLDDILGDILKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISD
QMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR
>Mature_206_residues
STIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACDSQRPSVVFINEDCFIHDASNSQRIKLIINQHPNTLFI
VFMAIANVHFDEYLLVRKNLLISSKSIKPESLDDILGDILKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISDQ
MNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR

Specific function: Positive regulator of capsular polysaccharide synthesis. RcsA and rcsB form a complex to promote transcription of the genes for capsule synthesis

COG id: COG2771

COG function: function code K; DNA-binding HTH domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH luxR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1788262, Length=207, Percent_Identity=100, Blast_Score=425, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RCSA_ECO57 (P69406)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B85813
- PIR:   B90965
- RefSeq:   NP_288412.1
- RefSeq:   NP_310717.1
- ProteinModelPortal:   P69406
- SMR:   P69406
- MINT:   MINT-1224774
- EnsemblBacteria:   EBESCT00000026378
- EnsemblBacteria:   EBESCT00000056504
- GeneID:   913009
- GeneID:   961951
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3041
- KEGG:   ecs:ECs2690
- GeneTree:   EBGT00050000011578
- HOGENOM:   HBG417356
- OMA:   EDCFIHE
- ProtClustDB:   PRK15411
- BioCyc:   ECOL83334:ECS2690-MONOMER
- GO:   GO:0005622
- InterPro:   IPR016032
- InterPro:   IPR000792
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00038
- SMART:   SM00421

Pfam domain/function: PF00196 GerE; SSF46894 Bipartite_resp_reg_C-effector

EC number: NA

Molecular weight: Translated: 23517; Mature: 23386

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS00622 HTH_LUXR_1; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACDSQRPSVVFINEDCFIH
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHEEECCCCCCEEEEECCEEEE
DASNSQRIKLIINQHPNTLFIVFMAIANVHFDEYLLVRKNLLISSKSIKPESLDDILGDI
ECCCCCEEEEEEECCCCEEEEEEEHHHHCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHH
LKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISDQMNIKAKTVSSHKGNIKRKI
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCHHHHH
KTHNKQVIYHVVRLTDNVTNGIFVNMR
HHCCHHEEEHEEEHHCCCCCCEEEEEC
>Mature Secondary Structure 
STIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACDSQRPSVVFINEDCFIH
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHEEECCCCCCEEEEECCEEEE
DASNSQRIKLIINQHPNTLFIVFMAIANVHFDEYLLVRKNLLISSKSIKPESLDDILGDI
ECCCCCEEEEEEECCCCEEEEEEEHHHHCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHH
LKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISDQMNIKAKTVSSHKGNIKRKI
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCHHHHH
KTHNKQVIYHVVRLTDNVTNGIFVNMR
HHCCHHEEEHEEEHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796