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The map label for this gene is ycjQ [H]

Identifier: 209398887

GI number: 209398887

Start: 1849793

End: 1850845

Strand: Direct

Name: ycjQ [H]

Synonym: ECH74115_1958

Alternate gene names: 209398887

Gene position: 1849793-1850845 (Clockwise)

Preceding gene: 209396657

Following gene: 209400921

Centisome position: 33.2

GC content: 54.89

Gene sequence:

>1053_bases
ATGAAAAAGTTAGTAGCCACAGCACCGCGCGTTGCTGCGCTGGTTGAGTATGAAGATCGGGCGATTTTAGCCAATGAAGT
GAAGATCCGCGTGCGTTTCGGTGCACCGAAACACGGAACGGAAGTGGTCGACTTCCGCGCCGCCAGCCCGTTTATCGATG
AAGACTTTAACGGCGAATGGCAGATGTTCACCCCGCGTCCGGCAGATGCGCCGCGCGGCATTGAGTTTGGCAAATTCCAG
CTTGGCAACATGGTGGTTGGCGACATTATCGAGTGCGGCAGCGACGTTACCGACTACGCGGTGGGCGACAGCGTATGCGG
CTACGGCCCGCTCTCCGAGACGATCATCATTAACGCAGTGAATAACTACAAGCTGCGCAAAATGCCGGAAGGCAGCTCCT
GGAAAAACGCTGTCTGCTACGACCCGGCGCAGTTTGCCATGAGTGGCGTTCGCGATGCCAACGTACGCGTAGGGGATTTT
GTAGTGGTGGTAGGGCTTGGCGCGATCGGTCAAATTGCCATCCAACTGGCTAAACGCGCTGGCGCGTCGGTGGTAATTGG
CGTCGATCCTATTGCCCATCGTTGTGATATTGCTCGTCGTCACGGTGCGGATTTCTGCCTTAATCCCATTGGCACTGACG
TAGGCAAAGAGATCAAAACGCTGACCGGCAAGCAGGGTGCCGATGTGATTATCGAAACCAGCGGTTACGCCGACGCGCTG
CAGTCGGCGCTGCGCGGCCTGGCTTACGGTGGCACCATCTCCTATGTCGCGTTTGCTAAACCGTTTGCTGAAGGTTTTAA
CCTCGGACGCGAAGCGCATTTCAATAACGCCAAAATTGTCTTCTCTCGCGCGTGCAGTGAACCGAACCCGGATTATCCGC
GCTGGAGCCGTAAGCGTATTGAAGAAACCTGCTGGAAACTGCTGATGAACGGTTATCTCAATTGCGAAGATTTAATCGAC
CCGGTAGTGACCTTTGCCAACAGCCCGGAAAGCTACATGCAGTATGTCGATCAGCATCCGGAACAGAGCATCAAAATGGG
CGTCACGTTTTAA

Upstream 100 bases:

>100_bases
GGTGATTATGTATGCGCTTTCGGAACGTTTTATTAAGAGTGGTTTGACCGCCGGTGGCGTGAAGGGCTAAAGCGGCCAGT
TTCTTTACAAGGAGTTTTAC

Downstream 100 bases:

>100_bases
TTCAAAGGAATGAAAAAATGAAAATAGGCACACAGAATCAGGCGTTCTTCCCGGAAAATATTCTGGAGAAATTTCGTTAT
ATCAAAGAGATGGGCTTCGA

Product: oxidoreductase, zinc-binding dehydrogenase family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQ
LGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETIIINAVNNYKLRKMPEGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
QSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRIEETCWKLLMNGYLNCEDLID
PVVTFANSPESYMQYVDQHPEQSIKMGVTF

Sequences:

>Translated_350_residues
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQ
LGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETIIINAVNNYKLRKMPEGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
QSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRIEETCWKLLMNGYLNCEDLID
PVVTFANSPESYMQYVDQHPEQSIKMGVTF
>Mature_350_residues
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQ
LGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETIIINAVNNYKLRKMPEGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
QSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRIEETCWKLLMNGYLNCEDLID
PVVTFANSPESYMQYVDQHPEQSIKMGVTF

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787572, Length=350, Percent_Identity=99.1428571428571, Blast_Score=721, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17562876, Length=154, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323099, Length=138, Percent_Identity=31.8840579710145, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322619, Length=216, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319955, Length=216, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 38231; Mature: 38231

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEW
CCCCHHCCCHHHEEEEECCCEEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCE
QMFTPRPADAPRGIEFGKFQLGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETIIINAV
EEECCCCCCCCCCCCCCCEEECCCHHHHHHHCCCCCHHHHCCCCCCCCCCCCCEEEEEEC
NNYKLRKMPEGSSWKNAVCYDPAQFAMSGVRDANVRVGDFVVVVGLGAIGQIAIQLAKRA
CCCEEEECCCCCCCCCCEEECHHHHHHHCCCCCCCEECCEEEEEECCHHHHHHHHHHHHC
GASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
CCEEEEECCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHH
QSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRI
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHH
EETCWKLLMNGYLNCEDLIDPVVTFANSPESYMQYVDQHPEQSIKMGVTF
HHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHCCCCCC
>Mature Secondary Structure
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEW
CCCCHHCCCHHHEEEEECCCEEEEEEEEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCE
QMFTPRPADAPRGIEFGKFQLGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETIIINAV
EEECCCCCCCCCCCCCCCEEECCCHHHHHHHCCCCCHHHHCCCCCCCCCCCCCEEEEEEC
NNYKLRKMPEGSSWKNAVCYDPAQFAMSGVRDANVRVGDFVVVVGLGAIGQIAIQLAKRA
CCCEEEECCCCCCCCCCEEECHHHHHHHCCCCCCCEECCEEEEEECCHHHHHHHHHHHHC
GASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
CCEEEEECCCHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHH
QSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRI
HHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHHH
EETCWKLLMNGYLNCEDLIDPVVTFANSPESYMQYVDQHPEQSIKMGVTF
HHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]