BacMap

Definition	Escherichia coli O157:H7 str. EC4115, complete genome.
Accession	NC_011353
Length	5,572,075

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The map label for this gene is ybbO [H]

Identifier: 209398805

GI number: 209398805

Start: 615404

End: 616213

Strand: Reverse

Name: ybbO [H]

Synonym: ECH74115_0597

Alternate gene names: 209398805

Gene position: 616213-615404 (Counterclockwise)

Preceding gene: 209396189

Following gene: 209400420

Centisome position: 11.06

GC content: 54.69

Gene sequence:

>810_bases
ATGACTCATAAAGCAACGGAGATCCTGACAGGTAAAGTTATGCAAAAATCGGTCTTAATTACCGGATGTTCCAGTGGAAT
TGGCCTGGAAAGCGCGCTCGAATTAAAACGCCAGGGTTTTCATGTGCTGGCAGGTTGCCGGAAACCGGATGATGTTGAGC
GCATGAACAGCATGGGATTTACCGGCGTGTTGATCGATCTGGATTCACCAGAAAGTGTTGATCGCGCAGCCGACGAGGTG
ATCGCCCTGACCGATAATTGTCTGTATGGGATCTTTAACAATGCCGGATTCGGCATGTATGGCCCCCTTTCCACCATCAG
CCGTGCGCAGATGGAACAGCAGTTTTCCGCCAACTTTTTCGGCGCACACCAGCTCACCATGCGCCTGTTACCCGCGATGT
TGCCGCACGGTGAAGGGCGTATTGTGATGACCTCATCGGTGATGGGATTAATCTCCACACCGGGTCGTGGCGCTTACGCG
GCCAGTAAATATGCGCTGGAGGCGTGGTCAGACGCGCTGCGCATGGAGCTGCGCCGCAGCGGAATTAAAGTCAGCCTGAT
CGAACCCGGTCCCATTCGTACTCGCTTCACCGACAACGTCAACCAGACGCAAAGTGATAAACCAGTCGAAAATCCCGGCA
TCGCCGCCCGCTTTACGTTGGGACCGGAAGCGGTGGTGGACAAAGTACGCCATGCTTTTATTAGCGAGAAGCCGAAGATG
CGCTATCCGGTAACGCTGGTGACCTGGGCGGTAATGGTGCTTAAGCGCCTGCTGCCGGGGCGCGTGATGGACAAAATATT
GCAGGGGTGA

Upstream 100 bases:

>100_bases
AAGCCACAATGGATGCAGGATGACGGTATTCATCCCAACCGCGACGCCCAGCCGTTTATTGCCGACTGGATGGCGAAGCA
GTTGCAGCCTTTAGTAAATC

Downstream 100 bases:

>100_bases
GTTGAAGCGCGCGCTTAAGCCCCCATGTCAAAGAAAATATCGACAACAGAGAGCGACTCCATGTCCGTAGAAAATATTGT
CAACATTAACGAATCTAACC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEV
IALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYA
ASKYALEAWSDALRMELRRSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKM
RYPVTLVTWAVMVLKRLLPGRVMDKILQG

Sequences:

>Translated_269_residues
MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEV
IALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYA
ASKYALEAWSDALRMELRRSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKM
RYPVTLVTWAVMVLKRLLPGRVMDKILQG
>Mature_268_residues
THKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEVI
ALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAA
SKYALEAWSDALRMELRRSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKMR
YPVTLVTWAVMVLKRLLPGRVMDKILQG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=188, Percent_Identity=39.3617021276596, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI40548397, Length=262, Percent_Identity=30.5343511450382, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI214010158, Length=262, Percent_Identity=30.5343511450382, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI214010156, Length=262, Percent_Identity=30.5343511450382, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI22758144, Length=262, Percent_Identity=30.5343511450382, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI50726952, Length=186, Percent_Identity=38.7096774193548, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI150247226, Length=254, Percent_Identity=33.0708661417323, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI22507405, Length=286, Percent_Identity=30.4195804195804, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI44680136, Length=289, Percent_Identity=29.0657439446367, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI44680133, Length=289, Percent_Identity=29.0657439446367, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI17738292, Length=289, Percent_Identity=29.0657439446367, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI19743808, Length=281, Percent_Identity=30.6049822064057, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI119392083, Length=213, Percent_Identity=36.6197183098592, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI223718074, Length=195, Percent_Identity=33.8461538461538, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=31.8181818181818, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI7706318, Length=269, Percent_Identity=26.3940520446097, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI157739938, Length=193, Percent_Identity=31.6062176165803, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4504503, Length=206, Percent_Identity=31.5533980582524, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI142976729, Length=260, Percent_Identity=27.3076923076923, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI40807363, Length=254, Percent_Identity=30.7086614173228, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI210032110, Length=191, Percent_Identity=29.8429319371728, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI32483357, Length=189, Percent_Identity=25.3968253968254, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI32455239, Length=190, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI5031765, Length=190, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI4503817, Length=227, Percent_Identity=26.8722466960352, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786701, Length=269, Percent_Identity=99.6282527881041, Blast_Score=555, Evalue=1e-159,
Organism=Escherichia coli, GI87082100, Length=206, Percent_Identity=31.0679611650485, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1789378, Length=213, Percent_Identity=28.169014084507, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787335, Length=192, Percent_Identity=26.0416666666667, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082160, Length=190, Percent_Identity=25.2631578947368, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI2367365, Length=189, Percent_Identity=30.6878306878307, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=287, Percent_Identity=29.9651567944251, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI32563809, Length=303, Percent_Identity=26.7326732673267, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17507613, Length=303, Percent_Identity=26.7326732673267, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17557780, Length=297, Percent_Identity=28.6195286195286, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI193210355, Length=264, Percent_Identity=30.6818181818182, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17570069, Length=194, Percent_Identity=31.9587628865979, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71997402, Length=194, Percent_Identity=29.3814432989691, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=239, Percent_Identity=28.8702928870293, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=275, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=265, Percent_Identity=26.7924528301887, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17559962, Length=203, Percent_Identity=30.0492610837438, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=189, Percent_Identity=30.1587301587302, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323882, Length=203, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=33.5051546391753, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24651139, Length=237, Percent_Identity=31.6455696202532, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356301, Length=222, Percent_Identity=27.9279279279279, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24643142, Length=205, Percent_Identity=27.3170731707317, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28571526, Length=186, Percent_Identity=31.1827956989247, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45554248, Length=200, Percent_Identity=32.5, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640117, Length=200, Percent_Identity=32.5, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=28.125, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19922066, Length=185, Percent_Identity=27.027027027027, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=28.7234042553192, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29430; Mature: 29298

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNSMGF
CCCCHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCEEECCCCCHHHHHHHCCCC
TGVLIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFF
EEEEEECCCCHHHHHHHHHEEEHHCCCEEEHCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
GAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRRS
CHHHHHHHHHHHHCCCCCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKM
CCEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCC
RYPVTLVTWAVMVLKRLLPGRVMDKILQG
CCCHHHHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure 
THKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNSMGF
CCCHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHCCCCEEECCCCCHHHHHHHCCCC
TGVLIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFF
EEEEEECCCCHHHHHHHHHEEEHHCCCEEEHCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
GAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRRS
CHHHHHHHHHHHHCCCCCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKM
CCEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCC
RYPVTLVTWAVMVLKRLLPGRVMDKILQG
CCCHHHHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]