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The map label for this gene is fixA [H]

Identifier: 209398664

GI number: 209398664

Start: 46749

End: 47582

Strand: Direct

Name: fixA [H]

Synonym: ECH74115_0045

Alternate gene names: 209398664

Gene position: 46749-47582 (Clockwise)

Preceding gene: 209399844

Following gene: 209400372

Centisome position: 0.84

GC content: 51.08

Gene sequence:

>834_bases
ATGATATCTGTAATTAACACCACCGATATGAACGACGTTTCCTTCATGATTTCTGGAGATGCAATGAAGATTATTACTTG
CTATAAGTGCGTGCCTGATGAACAGGATATTGCGGTCAATAATGCTGATGGTTCGTTAGACTTCAGTAAAGCCGATGCCA
AAATAAGCCAATACGATCTCAACGCTATTGAAGCGGCTTGCCAGCTAAAGCAACAGGCAGCAGAGGCGCAGGTGACGGCC
CTAAGTGTGGGCGGTAAAGCCCTGACCAACGCCAAAGGGCGTAAAGATGTGCTATCGCGCGGTCCGGATGAACTGATTGT
GGTGATTGATGACCAGTTCGAGCAGGCACTGCCGCAACAAACGGCGAGCGCACTGGCTGCAGCCGCCCAGAAAGCAGGCT
TTGATTTGATCCTCTGTGGCGATGGTTCTTCCGACCTTTATGCCCAGCAGGTTGGTTTGCTGGTAGGCGAAATCCTCAAT
ATTCCGGCAGTTAACGGCGTCAGCAAAATTATCTCCCTGACGGCAGATACCCTCACCGTTGAGCGCGAACTGGAAGATGA
AACCGAAACCTTAAGCATTCCACTGCCTGCGGTTGTTGCTGTTTCCACTGATATCAACTCCCCACAAATTCCTTCGATGA
AAGCCATTCTCGGCGCGGCGAAAAAGCCAGTCCAGGTATGGTCGGCGGCGGATATCGGTTTTAACGCAGAGGCAGCATGG
TCAGAACAACAGGTTGCCGCGCCGAAACAGCGCGAGCGTCAGCGCATCGTGATTGAAGGCGACGGCGAAGAACAGATCGC
CGCATTTGCTGAAAATCTTCGCAAAGTCATTTAA

Upstream 100 bases:

>100_bases
TCAATATTGGTGAGGAACTTAACAATATTGAAAGTTGGATTTATCTGCGTGTGACATTTTCAATATTGGTGATTAAAGTT
TTATTTCCAAATTAAAGGGC

Downstream 100 bases:

>100_bases
TTACAGGGGATGCTATGAACACGTTTTCTCAAGTCTGGGTATTCAGCGATACCCCTTCTCGTCTGCCGGAACTGATGAAC
GGTGCGCAGGCTTTAGCTAA

Product: putative electron transfer flavoprotein FixA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MISVINTTDMNDVSFMISGDAMKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTA
LSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILN
IPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAW
SEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI

Sequences:

>Translated_277_residues
MISVINTTDMNDVSFMISGDAMKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTA
LSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILN
IPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAW
SEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
>Mature_277_residues
MISVINTTDMNDVSFMISGDAMKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTA
LSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILN
IPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAW
SEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI

Specific function: Required for anaerobic carnitine reduction. May bring reductant to CaiA [H]

COG id: COG2086

COG function: function code C; Electron transfer flavoprotein, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF beta-subunit/fixA family [H]

Homologues:

Organism=Homo sapiens, GI4503609, Length=192, Percent_Identity=31.7708333333333, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI62420877, Length=192, Percent_Identity=31.7708333333333, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI87081682, Length=256, Percent_Identity=100, Blast_Score=511, Evalue=1e-146,
Organism=Escherichia coli, GI2367123, Length=257, Percent_Identity=55.6420233463035, Blast_Score=270, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000049
- InterPro:   IPR014730
- InterPro:   IPR012255
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF [H]

EC number: NA

Molecular weight: Translated: 29388; Mature: 29388

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: PS01065 ETF_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVINTTDMNDVSFMISGDAMKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDL
CEEEEECCCCCCEEEEEECCCEEEEEEEECCCCCCCEEEECCCCCCCCCHHCCCHHHHHH
NAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQ
HHHHHHHHHHHHHHHHEEEEEECCCHHHCCCCCHHHHHHCCCCEEEEEECCHHHHHHHHH
TASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTV
HHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEE
ERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAW
EHHHCCCCCEEECCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCC
SEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
CCHHHCCCCHHCCCEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MISVINTTDMNDVSFMISGDAMKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDL
CEEEEECCCCCCEEEEEECCCEEEEEEEECCCCCCCEEEECCCCCCCCCHHCCCHHHHHH
NAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQ
HHHHHHHHHHHHHHHHEEEEEECCCHHHCCCCCHHHHHHCCCCEEEEEECCHHHHHHHHH
TASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTV
HHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEE
ERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAW
EHHHCCCCCEEECCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCC
SEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
CCHHHCCCCHHCCCEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA