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The map label for this gene is yebS

Identifier: 209398570

GI number: 209398570

Start: 2424382

End: 2425665

Strand: Direct

Name: yebS

Synonym: ECH74115_2566

Alternate gene names: 209398570

Gene position: 2424382-2425665 (Clockwise)

Preceding gene: 209397060

Following gene: 209400762

Centisome position: 43.51

GC content: 50.39

Gene sequence:

>1284_bases
ATGGCTCTTAACACACCACAAATTACGCCGACAAAAAAGATAACAGTGAGGGCAATCGGCGAGGAACTGCCGCGTGGTGA
TTACCAACGTTGCCCGCAATGTGACATGCTGTTTAGCCTGCCCGAGATAAATTCTCATCAAAGTGCCTATTGTCCGCGCT
GTCAGGCAAAAATTCGTGACGGGCGCGACTGGTCGCTAACGCGCCTGGCGGCAATGGCCTTCACCATGCTGTTGCTGATG
CCGTTTGCCTGGGGCGAACCGCTGTTGCATATCTGGCTGTTAGGCATTCGTATTGACGCCAACGTTATGCAAGGCATCTG
GCAAATGACCAAACAGGGCGATGCGATAACGGGGTCGATGGTCTTTTTCTGCGTTATTGGTGCCCCGCTCATTCTGGTGA
CCTCCATAGCTTATTTATGGTTTGGTAACCGACTGGGAATGAATCTACGCCCGGTACTGCTGATGCTTGAGCGACTTAAA
GAGTGGGTAATGCTCGATATCTACCTGGTCGGCATTGGCGTTGCTTCTATAAAGGTACAGGATTATGCCCATATCCAGGC
GGGTGTCGGCTTGTTCTCTTTTGTGGCGTTGGTGATTTTAACGACGGTGACGTTGTCACATCTTAATGTCGAGGAGCTGT
GGGAGCGATTTTATCCGCAGCGCCCCGCTACGCGTAGGGACGAGAAACTTCGTGTCTGTCTTGGGTGCCATTTTACCGGC
TATCCTGATCAGCGTGGTCGCTGCCCGCGTTGTCATATTCCGCTACGCCTGCGTCGCCGTCATAGTCTGCAAAAATGCTG
GGCGGCGCTGTTAGCGTCAATCGTTTTATTGTTACCTGCCAACCTGTTGCCTATTTCTATCATTTATCTGAACGGAGGAC
GGCAGGAAGATACAATTCTTTCCGGAATTATGTCGCTGGCAAGTAGCAACATTGCGGTTGCAGGAATCGTGTTTATCGCC
AGTATTCTGGTACCGTTTACTAAAGTGATCGTCATGTTCACTTTACTGTTGAGCATTCATTTTAAATGCCAGCAAGGTTT
ACGCACACGCATTCTGTTACTGCGGATGGTGACCTGGATTGGTCGCTGGTCGATGCTCGACCTGTTTGTCATATCTTTAA
CCATGTCGCTGATTAATCGCGATCAGATCCTCGCTTTTACTATGGGACCGGCTGCGTTTTATTTCGGCGCAGCGGTAATT
TTGACTATTCTTGCTGTGGAATGGCTGGACAGCCGCTTACTTTGGGATGCACATGAGTCAGGAAACGCCCGCTTCGACGA
CTGA

Upstream 100 bases:

>100_bases
ACTGCCAGCCTATTAAAATAAGCATTAAATGCGTTAATGCTCAAGATCATTCCCATCATGGGTTAAGATTAATGTTAATT
CTTATTACATTTGGCACGTC

Downstream 100 bases:

>100_bases
AGCGCAGATTAAAAATAAACGCCGTATCTCACCTTTCTGGCTGCTGCCGTTCATCGCGCTAATGATTGCCGGTTGGCTGA
TTTGGGACAGTTATCAGGAC

Product: integral membrane protein, PqiA family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MALNTPQITPTKKITVRAIGEELPRGDYQRCPQCDMLFSLPEINSHQSAYCPRCQAKIRDGRDWSLTRLAAMAFTMLLLM
PFAWGEPLLHIWLLGIRIDANVMQGIWQMTKQGDAITGSMVFFCVIGAPLILVTSIAYLWFGNRLGMNLRPVLLMLERLK
EWVMLDIYLVGIGVASIKVQDYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFYPQRPATRRDEKLRVCLGCHFTG
YPDQRGRCPRCHIPLRLRRRHSLQKCWAALLASIVLLLPANLLPISIIYLNGGRQEDTILSGIMSLASSNIAVAGIVFIA
SILVPFTKVIVMFTLLLSIHFKCQQGLRTRILLLRMVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAAFYFGAAVI
LTILAVEWLDSRLLWDAHESGNARFDD

Sequences:

>Translated_427_residues
MALNTPQITPTKKITVRAIGEELPRGDYQRCPQCDMLFSLPEINSHQSAYCPRCQAKIRDGRDWSLTRLAAMAFTMLLLM
PFAWGEPLLHIWLLGIRIDANVMQGIWQMTKQGDAITGSMVFFCVIGAPLILVTSIAYLWFGNRLGMNLRPVLLMLERLK
EWVMLDIYLVGIGVASIKVQDYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFYPQRPATRRDEKLRVCLGCHFTG
YPDQRGRCPRCHIPLRLRRRHSLQKCWAALLASIVLLLPANLLPISIIYLNGGRQEDTILSGIMSLASSNIAVAGIVFIA
SILVPFTKVIVMFTLLLSIHFKCQQGLRTRILLLRMVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAAFYFGAAVI
LTILAVEWLDSRLLWDAHESGNARFDD
>Mature_426_residues
ALNTPQITPTKKITVRAIGEELPRGDYQRCPQCDMLFSLPEINSHQSAYCPRCQAKIRDGRDWSLTRLAAMAFTMLLLMP
FAWGEPLLHIWLLGIRIDANVMQGIWQMTKQGDAITGSMVFFCVIGAPLILVTSIAYLWFGNRLGMNLRPVLLMLERLKE
WVMLDIYLVGIGVASIKVQDYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFYPQRPATRRDEKLRVCLGCHFTGY
PDQRGRCPRCHIPLRLRRRHSLQKCWAALLASIVLLLPANLLPISIIYLNGGRQEDTILSGIMSLASSNIAVAGIVFIAS
ILVPFTKVIVMFTLLLSIHFKCQQGLRTRILLLRMVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAAFYFGAAVIL
TILAVEWLDSRLLWDAHESGNARFDD

Specific function: Unknown

COG id: COG2995

COG function: function code S; Uncharacterized paraquat-inducible protein A

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pqiA family

Homologues:

Organism=Escherichia coli, GI1788137, Length=427, Percent_Identity=100, Blast_Score=871, Evalue=0.0,
Organism=Escherichia coli, GI1787183, Length=397, Percent_Identity=29.4710327455919, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YEBS_ECO57 (P0AD04)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   G90946
- RefSeq:   NP_288270.1
- RefSeq:   NP_310570.1
- ProteinModelPortal:   P0AD04
- EnsemblBacteria:   EBESCT00000025678
- EnsemblBacteria:   EBESCT00000057922
- GeneID:   912855
- GeneID:   961806
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z2880
- KEGG:   ecs:ECs2543
- GeneTree:   EBGT00050000011519
- HOGENOM:   HBG303313
- OMA:   MMSLVTR
- ProtClustDB:   CLSK870030
- BioCyc:   ECOL83334:ECS2543-MONOMER
- InterPro:   IPR005219
- InterPro:   IPR011031
- InterPro:   IPR007498
- TIGRFAMs:   TIGR00155

Pfam domain/function: PF04403 PqiA

EC number: NA

Molecular weight: Translated: 48274; Mature: 48143

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS51008 MULTIHEME_CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x21557be4)-; HASH(0x20a27850)-; HASH(0x20e37d70)-; HASH(0x2153f96c)-; HASH(0x213f6090)-; HASH(0x213a5a08)-; HASH(0x21778d68)-; HASH(0x213b643c)-;

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNTPQITPTKKITVRAIGEELPRGDYQRCPQCDMLFSLPEINSHQSAYCPRCQAKIRD
CCCCCCCCCCCCHHHHEEHHHHCCCCCHHCCCCCCCEECCCCCCCCCCCCCCCHHHHCCC
GRDWSLTRLAAMAFTMLLLMPFAWGEPLLHIWLLGIRIDANVMQGIWQMTKQGDAITGSM
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECHHHHHHHHHHHHCCCCCHHHH
VFFCVIGAPLILVTSIAYLWFGNRLGMNLRPVLLMLERLKEWVMLDIYLVGIGVASIKVQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEH
DYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFYPQRPATRRDEKLRVCLGCHFTG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCC
YPDQRGRCPRCHIPLRLRRRHSLQKCWAALLASIVLLLPANLLPISIIYLNGGRQEDTIL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHH
SGIMSLASSNIAVAGIVFIASILVPFTKVIVMFTLLLSIHFKCQQGLRTRILLLRMVTWI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRWSMLDLFVISLTMSLINRDQILAFTMGPAAFYFGAAVILTILAVEWLDSRLLWDAHES
CCHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
GNARFDD
CCCCCCH
>Mature Secondary Structure 
ALNTPQITPTKKITVRAIGEELPRGDYQRCPQCDMLFSLPEINSHQSAYCPRCQAKIRD
CCCCCCCCCCCHHHHEEHHHHCCCCCHHCCCCCCCEECCCCCCCCCCCCCCCHHHHCCC
GRDWSLTRLAAMAFTMLLLMPFAWGEPLLHIWLLGIRIDANVMQGIWQMTKQGDAITGSM
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECHHHHHHHHHHHHCCCCCHHHH
VFFCVIGAPLILVTSIAYLWFGNRLGMNLRPVLLMLERLKEWVMLDIYLVGIGVASIKVQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEH
DYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFYPQRPATRRDEKLRVCLGCHFTG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCEEEEEEECCCC
YPDQRGRCPRCHIPLRLRRRHSLQKCWAALLASIVLLLPANLLPISIIYLNGGRQEDTIL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHH
SGIMSLASSNIAVAGIVFIASILVPFTKVIVMFTLLLSIHFKCQQGLRTRILLLRMVTWI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRWSMLDLFVISLTMSLINRDQILAFTMGPAAFYFGAAVILTILAVEWLDSRLLWDAHES
CCHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHEEECCCC
GNARFDD
CCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796