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The map label for this gene is mpaA

Identifier: 209398476

GI number: 209398476

Start: 1864699

End: 1865427

Strand: Reverse

Name: mpaA

Synonym: ECH74115_1970

Alternate gene names: 209398476

Gene position: 1865427-1864699 (Counterclockwise)

Preceding gene: 209397780

Following gene: 209398083

Centisome position: 33.48

GC content: 54.87

Gene sequence:

>729_bases
ATGACCGTAACCCGCCCACGCGCCGAACGCGGCGCATTTCCGCCCGGAACAGAACATTACGGACGTTCATTATTGGGCGC
GCCGTTAATCTGGTTTCCGGCCCCTGCAGCCAGTCGCGAAAGTGGTTTGATTCTGGCTGGCACTCACGGTGATGAAAACT
CTTCGGTCGTCACGCTCTCCTGTGCTCTGCGGACTTTGACACCTTCTTTGCGCCGCCATCATGTGGTGCTGTGTGTGAAT
CCTGACGGCTGCCAGCTGGGGTTACGGGCCAATGCTAATGGTGTGGATTTAAACAGAAACTTTCCGGCGGCGAACTGGAA
GGAAGGTGAAACGGTTTATCGCTGGAACAGCGCCGCTGAAGAACGTGATGTCGTATTACTGACAGGTGACAAACCTGGCT
CCGAACCTGAAACCCAGGCGCTGTGCCAGCTTATACACCGCATTCAACCTGCCTGGGTGGTCTCATTCCACGATCCACTG
GCCTGTATTGAAGATCCCAGACACAGCGAATTAGGCGAATGGCTGGCTCAGGCGTTTGAATTGCCTCTGGTAACCAGCGT
CGGTTATGAAACGCCTGGCTCTTTCGGCAGTTGGTGTGCAGATCTGAACTTGCATTGCATCACCGCAGAGTTTCCGCCCA
TCTCCTCCGACGAAGCCAGCGAAAAATATCTCTTTGCGATGGCAAACTTGCTGCGCTGGCATCCTAAAGATGCAATTCGC
CCGTCGTGA

Upstream 100 bases:

>100_bases
AGTGATACAAGATCGATGACATAGCGTTGAAGAAAAGGATTTGATAATCCGCAAAATTTGCACAACACTGCCTGTAATAC
TTCCTGAACCAGAGACGATC

Downstream 100 bases:

>100_bases
ACTGAAGCGCCGGTTCCACATCTACCGCCAGCCAGGTCGGTCCGTCAAGATCGGCGAAACTGACCTGCGGCACCAGCGGT
AAAGCGGCGCTAATGGCCCG

Product: murein peptide amidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MTVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASRESGLILAGTHGDENSSVVTLSCALRTLTPSLRRHHVVLCVN
PDGCQLGLRANANGVDLNRNFPAANWKEGETVYRWNSAAEERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPL
ACIEDPRHSELGEWLAQAFELPLVTSVGYETPGSFGSWCADLNLHCITAEFPPISSDEASEKYLFAMANLLRWHPKDAIR
PS

Sequences:

>Translated_242_residues
MTVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASRESGLILAGTHGDENSSVVTLSCALRTLTPSLRRHHVVLCVN
PDGCQLGLRANANGVDLNRNFPAANWKEGETVYRWNSAAEERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPL
ACIEDPRHSELGEWLAQAFELPLVTSVGYETPGSFGSWCADLNLHCITAEFPPISSDEASEKYLFAMANLLRWHPKDAIR
PS
>Mature_241_residues
TVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASRESGLILAGTHGDENSSVVTLSCALRTLTPSLRRHHVVLCVNP
DGCQLGLRANANGVDLNRNFPAANWKEGETVYRWNSAAEERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPLA
CIEDPRHSELGEWLAQAFELPLVTSVGYETPGSFGSWCADLNLHCITAEFPPISSDEASEKYLFAMANLLRWHPKDAIRP
S

Specific function: Unknown

COG id: COG2866

COG function: function code E; Predicted carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI226510938, Length=242, Percent_Identity=100, Blast_Score=497, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MPAA_ECO57 (P0ACV7)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A99867
- PIR:   H85751
- RefSeq:   NP_287862.1
- RefSeq:   NP_309932.1
- ProteinModelPortal:   P0ACV7
- EnsemblBacteria:   EBESCT00000028453
- EnsemblBacteria:   EBESCT00000056088
- GeneID:   912455
- GeneID:   961294
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z2448
- KEGG:   ecs:ECs1905
- GeneTree:   EBGT00050000010950
- HOGENOM:   HBG416130
- OMA:   GAPLLYF
- ProtClustDB:   PRK10602
- BioCyc:   ECOL83334:ECS1905-MONOMER
- GO:   GO:0006508
- InterPro:   IPR000834

Pfam domain/function: PF00246 Peptidase_M14

EC number: NA

Molecular weight: Translated: 26558; Mature: 26427

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASRESGLILAGTHGDENSSVVTLS
CCCCCCCHHCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCEEEEECCCCCCCCEEEEE
CALRTLTPSLRRHHVVLCVNPDGCQLGLRANANGVDLNRNFPAANWKEGETVYRWNSAAE
EHHHHHCHHHHHCEEEEEECCCCCEEEEEECCCCEECCCCCCCCCCCCCCEEEEECCCCC
ERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPLACIEDPRHSELGEWLAQAFE
CCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCHHHHHHHHHHHHC
LPLVTSVGYETPGSFGSWCADLNLHCITAEFPPISSDEASEKYLFAMANLLRWHPKDAIR
CCEEEECCCCCCCCHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
PS
CC
>Mature Secondary Structure 
TVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASRESGLILAGTHGDENSSVVTLS
CCCCCCHHCCCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCEEEEECCCCCCCCEEEEE
CALRTLTPSLRRHHVVLCVNPDGCQLGLRANANGVDLNRNFPAANWKEGETVYRWNSAAE
EHHHHHCHHHHHCEEEEEECCCCCEEEEEECCCCEECCCCCCCCCCCCCCEEEEECCCCC
ERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPLACIEDPRHSELGEWLAQAFE
CCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCHHHHHHHHHHHHC
LPLVTSVGYETPGSFGSWCADLNLHCITAEFPPISSDEASEKYLFAMANLLRWHPKDAIR
CCEEEECCCCCCCCHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
PS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796