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The map label for this gene is ddpA [H]

Identifier: 209398371

GI number: 209398371

Start: 1996774

End: 1998324

Strand: Reverse

Name: ddpA [H]

Synonym: ECH74115_2099

Alternate gene names: 209398371

Gene position: 1998324-1996774 (Counterclockwise)

Preceding gene: 209400569

Following gene: 209399112

Centisome position: 35.86

GC content: 50.61

Gene sequence:

>1551_bases
ATGAAGAGATCGATATCGTTTCGTCCCACATTGCTCGCGCTCGTCCTTGCCACAACTTTCCCGGTTGCGCACGCCGCCGT
ACCGAAAGATATGCTGGTGATTGGTAAGGCCGCCGATCCACAAACCCTCGACCCGGCGGTAACAATAGATAATAACGACT
GGACAGTGACCTACCCGTCTTATCAGCGACTGGTTCAGTACAAAACGGACGGTGATAAAGGCTCAACCGACGTTGAAGGC
GATCTGGCAAGTAGCTGGAAAGCGTCTAACGATCAAAAAGAGTGGACGTTCACCCTGAAAGATAATGCTAAATTTGCCGA
TGGCACACCTGTCACTGCCGAAGCAGTAAAACTCTCTTTTGAGCGGTTACTAAAAATCGGCCAGGGGCCAGCAGAAGCAT
TTCCCAAAGATTTAAAGATTGATGCTCCCGACGAACATACGGTGAAGTTTACCCTTAGCCAGCCATTTGCACCGTTCCTC
TACACGCTGGCGAATGACGGTGCATCCATTATCAATCCGGCGGTATTAAAGGAACATGCGGCGGATGATGCCCGCGGCTT
CCTCGCGCAAAATACCGCCGGTTCCGGACCATTTATGCTGAAAAGCTGGCAAAAAGGTCAGCAATTAGTTCTGGTGCCAA
ATCCGCATTACCCCGGCAATAAACCGAACTTTAAGCGAGTATCGGTAAAAATTATCGGTGAAAGTGCCTCCCGTCGCCTG
CAGCTCTCCCGTGGCGACATTGACATTGCCGATGCGCTGCCGGTGGATCAACTCAACGCCCTGAAGCAGGAAAACAAAGT
CAATGTGGCAGAGTATCCGTCACTGCGCGTCACCTATCTGTATCTGAATAACAGCAAAGCGCCACTTAATCAGGCGGATC
TGCGGCGGGCCATTTCCTGGTCTACCGATTATCAGGGCATGGTTAACGGCATTCTGAGTGGTAACGGAAAACAAATGCGC
GGCCCGATTCCGGAAGGCATGTGGGGCTACGATGCGACGGCAATGCAATACAACCATGACGAAACGAAAGCCAAAGCCGA
ATGGGATAAAGTGACGAGCAAACCCACCAGCCTGACGTTTCTCTACTCCGATAACGATCCGAACTGGGAACCGATCGCTC
TGGCAACACAATCCAGCCTCAACAAGCTGGGCATCAATGTGAAGCTGGAAAAGCTGGCGAACGCCACCATGCGCGACAGA
GTGGGTAAAGGTGATTACGACATTGCGATTGGCAACTGGAGTCCGGATTTTGCCGACCCGTATATGTTTATGAATTACTG
GTTTGAGTCAGACAAAAAAGGTCTGCCGGGTAACCGCTCGTTCTATGAAAACAGTGAGGTCGATAAGTTACTGCGCAATG
CGCTTGCGACCACCGACCAGACGCAGCGTACCCGAGACTACCAGCAGGCACAGAAAATCGTCATTGATGACGCTGCTTAT
GTGTACCTGTTCCAGAAAAACTACCAACTGGCGATGAACAAAGAGGTGAAAGGCTTTGTGTTCAATCCCATGCTGGAACA
GGTCTTCAATATCAATACCATGAGTAAATAA

Upstream 100 bases:

>100_bases
TTCGAATTACCCCAGGCAGCGAGTTACCCTCTGCTCGCTGATCAATTCACCTGTTTTATATCCCCTGGCACACAGCACGT
CAGTTAATCAGGAAACTGCC

Downstream 100 bases:

>100_bases
CGTGACCTTCTGGAGTATTTTACGCCAACGCTGCTGGGGGCTGGTGCTCGTGGTGGCGGGCGTCTGCGTGATTACGTTTA
TTATCTCGCATCTGATCCCC

Product: putative ABC transporter periplasmic-binding protein yddS precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MKRSISFRPTLLALVLATTFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEG
DLASSWKASNDQKEWTFTLKDNAKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMR
GPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDR
VGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK

Sequences:

>Translated_516_residues
MKRSISFRPTLLALVLATTFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEG
DLASSWKASNDQKEWTFTLKDNAKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMR
GPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDR
VGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK
>Mature_516_residues
MKRSISFRPTLLALVLATTFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEG
DLASSWKASNDQKEWTFTLKDNAKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMR
GPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDR
VGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=516, Percent_Identity=99.4186046511628, Blast_Score=1055, Evalue=0.0,
Organism=Escherichia coli, GI1789966, Length=524, Percent_Identity=26.7175572519084, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI87081878, Length=540, Percent_Identity=28.7037037037037, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI1787495, Length=518, Percent_Identity=26.4478764478764, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1787052, Length=521, Percent_Identity=26.1036468330134, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1789887, Length=526, Percent_Identity=25.2851711026616, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787551, Length=467, Percent_Identity=22.9122055674518, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789397, Length=529, Percent_Identity=24.007561436673, Blast_Score=107, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57629; Mature: 57629

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSISFRPTLLALVLATTFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPS
CCCCCCCCHHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCEEEECCC
YQRLVQYKTDGDKGSTDVEGDLASSWKASNDQKEWTFTLKDNAKFADGTPVTAEAVKLSF
HHHHEEEECCCCCCCCCCCCCHHHCCCCCCCCCEEEEEEECCCEECCCCCCHHHHHHHHH
ERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFLYTLANDGASIINPAVLKEHA
HHHHHCCCCHHHHCCCCCEECCCCCCEEEEEECCCCHHHHHHHHCCCHHHCCHHHHHHHC
ADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
CCHHHCEEECCCCCCCCEEECCCCCCCEEEEECCCCCCCCCCCCEEEEEEEEECCCCCEE
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISW
EEECCCEEHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHCC
STDYQGMVNGILSGNGKQMRGPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTF
CCCCCHHHHHHHCCCCCEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEE
LYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDRVGKGDYDIAIGNWSPDFADP
EECCCCCCCCEEEEEEHHHHHHHCCCEEHHHHHCCHHHHHCCCCCEEEEECCCCCCCCCC
YMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
HHEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCEE
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK
EEEEECCCEEEECCCCCCEEECHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRSISFRPTLLALVLATTFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPS
CCCCCCCCHHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCEEEECCC
YQRLVQYKTDGDKGSTDVEGDLASSWKASNDQKEWTFTLKDNAKFADGTPVTAEAVKLSF
HHHHEEEECCCCCCCCCCCCCHHHCCCCCCCCCEEEEEEECCCEECCCCCCHHHHHHHHH
ERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFLYTLANDGASIINPAVLKEHA
HHHHHCCCCHHHHCCCCCEECCCCCCEEEEEECCCCHHHHHHHHCCCHHHCCHHHHHHHC
ADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
CCHHHCEEECCCCCCCCEEECCCCCCCEEEEECCCCCCCCCCCCEEEEEEEEECCCCCEE
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISW
EEECCCEEHHCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHCC
STDYQGMVNGILSGNGKQMRGPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTF
CCCCCHHHHHHHCCCCCEECCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEE
LYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDRVGKGDYDIAIGNWSPDFADP
EECCCCCCCCEEEEEEHHHHHHHCCCEEHHHHHCCHHHHHCCCCCEEEEECCCCCCCCCC
YMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
HHEEHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCEE
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK
EEEEECCCEEEECCCCCCEEECHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]