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The map label for this gene is fic [H]

Identifier: 209398302

GI number: 209398302

Start: 4313847

End: 4314449

Strand: Reverse

Name: fic [H]

Synonym: ECH74115_4671

Alternate gene names: 209398302

Gene position: 4314449-4313847 (Counterclockwise)

Preceding gene: 209397201

Following gene: 209396064

Centisome position: 77.43

GC content: 52.9

Gene sequence:

>603_bases
ATGAGCGATAAATTCGGCGAAGGGCGCGATCCGTATCTTTATCCTGGCCTTGATATCATGCGTAACCGGCTGAACATCCG
CCAGCAACAACGGCTGGAACAGGCCGCTTACGAAATGACGGCGCTGCGTGCTGCGACCATTGAGCTTGGTCCGCTGGTGC
GCGGTTTACCGCATTTGCGCACTATCCATCGCCAGCTGTATCAGGATATTTTCGACTGGGCAGGGCAACTGCGTGAAGTT
GATATTTATCAGGGCGATACGCCGTTCTGCCACTTTGCTTATATCGAAAAAGAGGGCAATGCCCTGATGCAGGATCTGGA
GGAAGAAGGTTATCTGGTTGGCCTGGAGAAAACGAAGTTCGTCGAGCGGCTGGCGCATTACTATTGTGAAATCAACGTGC
TGCATCCCTTCCGGGTGGGAAGTGGTCTGGCACAGCGGATCTTCTTCGAGCAACTGGCGATTCATGCCGGATATCAACTG
AGCTGGCAGGGTATCGAAAAAGAGGCCTGGAATCAGGCAAATCAGAGTGGGGCAATGGGGGATCTCACCGCGTTGCAGAT
GATATTTAGCAAAGTGGTAAGCGAAGCCGGGGAATCTGAGTAA

Upstream 100 bases:

>100_bases
AATTTTCAGGCCAGTCGCCGTCTTGAAGGCGTCGAGATGCCTTTAGTCACTCTTACTGCCGCAGAGGCTTTAGCGCGCCT
TGAAGAGCTGAGGAGTCACT

Downstream 100 bases:

>100_bases
AATAGCGCGGTTCTTTCGTACCGGAGCCGCCATGATCCTGCTTATAGATAACTACGATTCTTTTACCTGGAACCTCTACC
AGTACTTTTGTGAACTGGGG

Product: cell filamentation protein Fic

Products: NA

Alternate protein names: Cell filamentation protein fic [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRAATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREV
DIYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKTKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
SWQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE

Sequences:

>Translated_200_residues
MSDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRAATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREV
DIYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKTKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
SWQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE
>Mature_199_residues
SDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRAATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREVD
IYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKTKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQLS
WQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE

Specific function: Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Involved in cell filamentation induced by cyclic AMP. May have some role in cell division [H]

COG id: COG2184

COG function: function code D; Protein involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 fido domain [H]

Homologues:

Organism=Escherichia coli, GI1789761, Length=200, Percent_Identity=99.5, Blast_Score=414, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003812 [H]

Pfam domain/function: PF02661 Fic [H]

EC number: NA

Molecular weight: Translated: 22990; Mature: 22859

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRAATIELGPLVRGLPHLR
CCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKTKF
HHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEECCCHHHHHHHHHCCEEEECHHHHH
VERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQLSWQGIEKEAWNQANQSGAMG
HHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCCCCH
DLTALQMIFSKVVSEAGESE
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRAATIELGPLVRGLPHLR
CCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKTKF
HHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEECCCHHHHHHHHHCCEEEECHHHHH
VERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQLSWQGIEKEAWNQANQSGAMG
HHHHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCCCCH
DLTALQMIFSKVVSEAGESE
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2546924; 2403545; 9278503; 7549107; 2007139 [H]