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The map label for this gene is dppB [H]

Identifier: 209398114

GI number: 209398114

Start: 4550022

End: 4551167

Strand: Reverse

Name: dppB [H]

Synonym: ECH74115_4911

Alternate gene names: 209398114

Gene position: 4551167-4550022 (Counterclockwise)

Preceding gene: 209396782

Following gene: 209399011

Centisome position: 81.68

GC content: 56.11

Gene sequence:

>1146_bases
GTGCCTCTGCGTGCAGCGCCATCCGGCAGCAATACTTCATTCCCTGCCCGACCTGGGCGGGAATTGATTTGTGAGCAATA
CAGACACGCAGTTCCAGGCTGCGGGTCACTACAGAGAATCCGGGTTATGTTGCAGTTTATTCTCCGACGTTTGGGACTCG
TCATCCCCACGTTTATCGGTATTACCCTTCTCACATTTGCCTTTGTCCACATGATCCCGGGCGATCCTGTGATGATCATG
GCGGGCGAACGTGGGATCTCCCCAGAGCGTCACGCGCAGTTGCTGGCTGAACTCGGCTTAGATAAACCGATGTGGCAGCA
GTATCTCCATTACATTTGGGGCGTTATGCATGGCGATCTAGGCATTTCAATGAAAAGCCGAATTCCGGTATGGGAAGAGT
TCGTGCCGCGCTTTCAGGCCACGCTGGAACTTGGCGTCTGCGCGATGATTTTTGCGACCGCGGTCGGCATTCCGGTTGGT
GTGCTGGCCGCGGTTAAACGCGGTTCCATTTTCGATCACACAGCGGTTGGCCTGGCGCTGACAGGTTATTCAATGCCTAT
CTTCTGGTGGGGCATGATGCTGATCATGCTGGTTTCGGTGCACTGGAACCTGACACCCGTCTCCGGTCGCGTGAGCGATA
TGGTGTTCCTCGATGATTCCAATCCGTTAACCGGTTTTATGCTGATCGACACCGCCATCTGGGGTGAAGACGGTAACTTT
ATCGATGCCGTCGCCCATATGATCTTGCCCGCCATTGTGCTGGGTACTATTCCGCTGGCGGTCATTGTGCGTATGACACG
CTCCTCGATGCTGGAAGTGCTGGGTGAAGATTACATCCGCACCGCGCGCGCCAAAGGGTTGACCCGCATGCGGGTGATTA
TCGTCCATGCGCTGCGTAACGCGATGCTGCCGGTAGTGACCGTTATCGGCCTCCAGGTGGGAACATTGCTGGCGGGGGCG
ATTCTGACCGAAACCATCTTCTCGTGGCCCGGTCTGGGGCGCTGGTTGATTGACGCACTGCAACGGCGCGATTATCCGGT
GGTGCAGGGCGGCGTATTGCTGGTGGCGACGATGATTATCCTCGTCAACCTGCTGGTCGATCTGCTGTATGGCGTGGTGA
ACCCGCGTATTCGTCATAAGAAGTAA

Upstream 100 bases:

>100_bases
GGTACGCAAAGAAGTTAAAGGCTATGTGGTTGATCCATTAGGCAAACATCACTTCGAAAACGTCTCTATCGAATAATTAA
AAGCCATACCCGGTGGTGCT

Downstream 100 bases:

>100_bases
GGGGTCATCATGTCACAGGTTACTGAAAATAAAGTGATTAGCGCGCCGGTACCGATGACCCCTTTACAGGAGTTCTGGCA
CTATTTTAAACGCAACAAAG

Product: dipeptide transporter permease DppB

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MPLRAAPSGSNTSFPARPGRELICEQYRHAVPGCGSLQRIRVMLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIM
AGERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISMKSRIPVWEEFVPRFQATLELGVCAMIFATAVGIPVG
VLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNF
IDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGA
ILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIRHKK

Sequences:

>Translated_381_residues
MPLRAAPSGSNTSFPARPGRELICEQYRHAVPGCGSLQRIRVMLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIM
AGERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISMKSRIPVWEEFVPRFQATLELGVCAMIFATAVGIPVG
VLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNF
IDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGA
ILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIRHKK
>Mature_380_residues
PLRAAPSGSNTSFPARPGRELICEQYRHAVPGCGSLQRIRVMLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMA
GERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISMKSRIPVWEEFVPRFQATLELGVCAMIFATAVGIPVGV
LAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWNLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFI
DAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAI
LTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPRIRHKK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=339, Percent_Identity=100, Blast_Score=673, Evalue=0.0,
Organism=Escherichia coli, GI1787053, Length=342, Percent_Identity=42.1052631578947, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1787761, Length=329, Percent_Identity=43.7689969604863, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI1787550, Length=283, Percent_Identity=38.1625441696113, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI1789888, Length=341, Percent_Identity=32.8445747800587, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1787497, Length=340, Percent_Identity=35.2941176470588, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1788504, Length=378, Percent_Identity=28.042328042328, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 42060; Mature: 41929

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLRAAPSGSNTSFPARPGRELICEQYRHAVPGCGSLQRIRVMLQFILRRLGLVIPTFIG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ITLLTFAFVHMIPGDPVMIMAGERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDL
HHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
GISMKSRIPVWEEFVPRFQATLELGVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLAL
CCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHEE
TGYSMPIFWWGMMLIMLVSVHWNLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNF
ECCCHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEEEECCCCCEEEEEEEHHHCCCCCCH
IDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMII
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LVNLLVDLLYGVVNPRIRHKK
HHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PLRAAPSGSNTSFPARPGRELICEQYRHAVPGCGSLQRIRVMLQFILRRLGLVIPTFIG
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ITLLTFAFVHMIPGDPVMIMAGERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDL
HHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
GISMKSRIPVWEEFVPRFQATLELGVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLAL
CCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHEE
TGYSMPIFWWGMMLIMLVSVHWNLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNF
ECCCHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEEEECCCCCEEEEEEEHHHCCCCCCH
IDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMII
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LVNLLVDLLYGVVNPRIRHKK
HHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]