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The map label for this gene is cheA [H]

Identifier: 209397867

GI number: 209397867

Start: 2481582

End: 2483540

Strand: Reverse

Name: cheA [H]

Synonym: ECH74115_2627

Alternate gene names: 209397867

Gene position: 2483540-2481582 (Counterclockwise)

Preceding gene: 209397424

Following gene: 209398753

Centisome position: 44.57

GC content: 53.04

Gene sequence:

>1959_bases
ATGGATATAAGCGATTTTTATCAGACATTTTTTGATGAAGCGGACGAACTGTTGGCTGATATGGAGCAGCATCTGCTGGT
TTTGCAGCCGGAAGCGCCAGATGCCGAACAATTGAATGCCATCTTTCGGGCTGCCCACTCGATCAAAGGAGGGGCAGGAA
CTTTTGGCTTCAGCGTTTTGCAGGAAACCACGCATCTGATGGAAAACCTGCTCGATGAAGCCAGACGAGGTGAGATGCAA
CTCAACACCGACATTATCAATCTGTTTTTGGAAACGAAGGACATCATGCAAGAACAGCTCGACGCTTATAAACAGTCGCA
AGAGCCGGATGCCGCCAGCTTCGATTATATCTGCCAGGCCTTGCGTCAACTGGCATTAGAAGCGAAAGGCGAAACGCCAT
CCGCAGTGACCCGATTAAGTGTGGTTGCCAAAAGTGAACCGCAAGATGAGCAGAGTCGCAGTCAGTTGCCGCGACGAATT
ATCCTTTCGCGCCTGAAGGCCAGCGAAGTCGACCTGCTGGAAGAAGAGCTGGGGCATCTGACAACGTTAACTGACGTGGT
GAAAGGGGCGGATTCTCTCTCGGCAATATTACCGGGCGATATCGCCGAAGATGACATCACAGCGGTACTCTGTTTTGTGA
TTGAAGCCGATCAGATTACCTTTGAAACAGTAGAAGTCTCGCCAAAAATATCCACCCCACCAGTGCTTAAACTGGCAGCC
GAACAAGCGCCAACCGGTCGCGTGGAGCGGGAAAAAACGACGCGTAGCAGTGAATCCACCAGCATCCGTGTAGCGGTAGA
AAAGGTTGATCAATTAATTAACCTCGTCGGCGAGCTGGTTATCACCCAGTCCATGCTTGCCCAGCGTTCCAGCGAACTGG
ACCCGGTTAATCATGGTGATTTGATTACCAGCATGGGGCAGTTACAACGTAACGCCCGTGATTTGCAGGAATCAGTGATG
TCGATTCGCATGATGCCGATGGAATATGTCTTTAGTCGCTATCCCCGGCTGGTGCGTGATCTGGCGGGAAAACTCGGCAA
GCAGGTAGAACTGACGCTGGTGGGCAGTTCCACCGAGCTCGACAAGAGCCTGATAGAACGCATTATCGACCCGCTGACCC
ACCTGGTACGCAATAGCCTCGATCACGGTATTGAACTGCCAGAAAAACGGCTCGCCGCAGGTAAAAACAGCGTCGGAAAT
TTAATTCTGTCTGCCGAACATCAGGGCGGCAACATTTGCATTGAAGTGACCGACGATGGGGCGGGGCTAAACCGTGAGCG
AATTCTGGCAAAAGCGGCCTCGCAAGGTTTGACTGTCAGCGAAAACATGAGCGACGACGAAGTCGCGATGCTGATATTTG
CACCAGGCTTCTCCACGGCAGAGCAGGTCACCGACGTCTCCGGGCGCGGCGTCGGCATGGACGTCGTTAAACGTAATATC
CAGGAGATGGGCGGTCATGTTGAAATCCAGTCGAAGCAGGGTACTGGCACTACGATCCGCATTTTACTGCCGCTGACGCT
GGCCATCCTCGACGGCATGTCCGTACGCGTTGCGGATGAAGTATTCATTCTGCCGCTGAATGCTGTTATGGAATCACTGC
AACCCCGTGAAGCCGATCTGCATCCACTGGCCGGCGGCGAGCGGGTGCTGGAAGTGCGGGGTGAATATCTGCCCATCGTC
GAACTGTGGAAAGTGTTCAACGTCGCGGGCGCGAAAACCGAAGCTACCCAGGGAATTGTGGTGATCTTACAAAGTGGCGG
TCGCCGCTACGCCTTGCTGGTGGATCAATTAATTGGTCAACATCAGGTTGTAGTTAAAAACCTTGAAAGTAACTATCGCA
AAGTCCCCGGCATTTCTGCTGCGACCATTCTTGGCGACGGCAGCGTGGCACTGATTGTTGATGTCTCCGCCTTGCAGGCG
ATAAACCGCGAACAACGTATGGCGAACACCGCCGCCTGA

Upstream 100 bases:

>100_bases
AGCCAGAATGAGCCAGTAAGCGCCCTGGAAAAACCTGAGGTTGCACCACAGGTCAGTGTTCCCACAATGCCATCAGCCGA
ACCGAGGTGACAGCGTGAGC

Downstream 100 bases:

>100_bases
ATGAGTAAAAAGGTAACAATATGACCGGTATGACGAATGTAACAAAGCTGGCCAGCGAGCCGTCAGGCCAGGAATTTCTG
GTATTTACCCTTGGTGATGA

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 652; Mature: 652

Protein sequence:

>652_residues
MDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIFRAAHSIKGGAGTFGFSVLQETTHLMENLLDEARRGEMQ
LNTDIINLFLETKDIMQEQLDAYKQSQEPDAASFDYICQALRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQLPRRI
ILSRLKASEVDLLEEELGHLTTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIEADQITFETVEVSPKISTPPVLKLAA
EQAPTGRVEREKTTRSSESTSIRVAVEKVDQLINLVGELVITQSMLAQRSSELDPVNHGDLITSMGQLQRNARDLQESVM
SIRMMPMEYVFSRYPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKRLAAGKNSVGN
LILSAEHQGGNICIEVTDDGAGLNRERILAKAASQGLTVSENMSDDEVAMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNI
QEMGGHVEIQSKQGTGTTIRILLPLTLAILDGMSVRVADEVFILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPIV
ELWKVFNVAGAKTEATQGIVVILQSGGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQA
INREQRMANTAA

Sequences:

>Translated_652_residues
MDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIFRAAHSIKGGAGTFGFSVLQETTHLMENLLDEARRGEMQ
LNTDIINLFLETKDIMQEQLDAYKQSQEPDAASFDYICQALRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQLPRRI
ILSRLKASEVDLLEEELGHLTTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIEADQITFETVEVSPKISTPPVLKLAA
EQAPTGRVEREKTTRSSESTSIRVAVEKVDQLINLVGELVITQSMLAQRSSELDPVNHGDLITSMGQLQRNARDLQESVM
SIRMMPMEYVFSRYPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKRLAAGKNSVGN
LILSAEHQGGNICIEVTDDGAGLNRERILAKAASQGLTVSENMSDDEVAMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNI
QEMGGHVEIQSKQGTGTTIRILLPLTLAILDGMSVRVADEVFILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPIV
ELWKVFNVAGAKTEATQGIVVILQSGGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQA
INREQRMANTAA
>Mature_652_residues
MDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIFRAAHSIKGGAGTFGFSVLQETTHLMENLLDEARRGEMQ
LNTDIINLFLETKDIMQEQLDAYKQSQEPDAASFDYICQALRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQLPRRI
ILSRLKASEVDLLEEELGHLTTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIEADQITFETVEVSPKISTPPVLKLAA
EQAPTGRVEREKTTRSSESTSIRVAVEKVDQLINLVGELVITQSMLAQRSSELDPVNHGDLITSMGQLQRNARDLQESVM
SIRMMPMEYVFSRYPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKRLAAGKNSVGN
LILSAEHQGGNICIEVTDDGAGLNRERILAKAASQGLTVSENMSDDEVAMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNI
QEMGGHVEIQSKQGTGTTIRILLPLTLAILDGMSVRVADEVFILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPIV
ELWKVFNVAGAKTEATQGIVVILQSGGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQA
INREQRMANTAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=652, Percent_Identity=99.3865030674847, Blast_Score=1310, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71195; Mature: 71195

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS00039 DEAD_ATP_HELICASE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIFRAAHSIKGGAGTFGFSVL
CCHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
QETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQLDAYKQSQEPDAASFDYICQA
HHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
LRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQLPRRIILSRLKASEVDLLEEELGHL
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIEADQITFETVEVSPKISTPPVLKLAA
HHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHEECCCEEEEEEEECCCCCCCHHHHHHH
EQAPTGRVEREKTTRSSESTSIRVAVEKVDQLINLVGELVITQSMLAQRSSELDPVNHGD
CCCCCCCCCHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
LITSMGQLQRNARDLQESVMSIRMMPMEYVFSRYPRLVRDLAGKLGKQVELTLVGSSTEL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHH
DKSLIERIIDPLTHLVRNSLDHGIELPEKRLAAGKNSVGNLILSAEHQGGNICIEVTDDG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEEEECCCCEEEEEECCCC
AGLNRERILAKAASQGLTVSENMSDDEVAMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNI
CCCCHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCCHHHHHCCCCCCCCHHHHHHHH
QEMGGHVEIQSKQGTGTTIRILLPLTLAILDGMSVRVADEVFILPLNAVMESLQPREADL
HHCCCEEEEEECCCCCCEEEHHHHHHHHHHCCCCEEEECCEEEEEHHHHHHHCCCCCCCC
HPLAGGERVLEVRGEYLPIVELWKVFNVAGAKTEATQGIVVILQSGGRRYALLVDQLIGQ
CCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEHHHHHHHHCC
HQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQAINREQRMANTAA
HHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIFRAAHSIKGGAGTFGFSVL
CCHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHH
QETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQLDAYKQSQEPDAASFDYICQA
HHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
LRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQLPRRIILSRLKASEVDLLEEELGHL
HHHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
TTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIEADQITFETVEVSPKISTPPVLKLAA
HHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHEECCCEEEEEEEECCCCCCCHHHHHHH
EQAPTGRVEREKTTRSSESTSIRVAVEKVDQLINLVGELVITQSMLAQRSSELDPVNHGD
CCCCCCCCCHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
LITSMGQLQRNARDLQESVMSIRMMPMEYVFSRYPRLVRDLAGKLGKQVELTLVGSSTEL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHH
DKSLIERIIDPLTHLVRNSLDHGIELPEKRLAAGKNSVGNLILSAEHQGGNICIEVTDDG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCEEEEEECCCCEEEEEECCCC
AGLNRERILAKAASQGLTVSENMSDDEVAMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNI
CCCCHHHHHHHHHHCCCEEECCCCCCCEEEEEEECCCCCHHHHHCCCCCCCCHHHHHHHH
QEMGGHVEIQSKQGTGTTIRILLPLTLAILDGMSVRVADEVFILPLNAVMESLQPREADL
HHCCCEEEEEECCCCCCEEEHHHHHHHHHHCCCCEEEECCEEEEEHHHHHHHCCCCCCCC
HPLAGGERVLEVRGEYLPIVELWKVFNVAGAKTEATQGIVVILQSGGRRYALLVDQLIGQ
CCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEHHHHHHHHCC
HQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQAINREQRMANTAA
HHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2002011; 9097040; 9278503; 3510184; 2832069; 2068106; 8555213; 8639521; 9020767; 9437425; 9636149 [H]