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The map label for this gene is glpC

Identifier: 209397793

GI number: 209397793

Start: 3126255

End: 3127445

Strand: Direct

Name: glpC

Synonym: ECH74115_3380

Alternate gene names: 209397793

Gene position: 3126255-3127445 (Clockwise)

Preceding gene: 209397429

Following gene: 209397027

Centisome position: 56.11

GC content: 53.99

Gene sequence:

>1191_bases
ATGAATGACACCAGCTTCGAAAACTGCATTAAGTGCACCGTCTGCACCACCGCCTGCCCAGTGAGCCGGGTGAATCCCGG
TTATCCAGGGCCAAAACAAGCCGGGCCGGATGGCGAGCGTCTGCGTTTAAAAGATGGCGCACTGTATGACGAGGCACTGA
AATATTGCATCAACTGCAAACGTTGCGAAGTCGCCTGCCCGTCCGATGTGAAGATTGGCGATATCATCCAGCGCGCACGG
GCGAAATATGACACCACGCGCCCGTCGCTGCGCAATTTTGTTTTAAGCCATACCGACCTGATGGGTAGCGTTTCCACGCC
GTTCGCACCAATCGTCAACACCGCTACCTCGCTGAAACCGGTGCGGCAGTTGCTTGATGCGGCGTTAAAAATCGATCATC
GCCGCACGCTACCGAAATACTCCTTCGGCACGTTTCGTCGCTGGTATCGCAGCGTGGCGGCTCAGCAAGCGCAGTATAAA
GACCAGGTCGCTTTCTTTCACGGCTGCTTCGTTAACTACAACCATCCGCAGTTAGGTAAAGATTTAATTAAAGTGCTCAA
CGCAATGGGTACCGGTGTACAACTGCTCAGCAAAGAAAAATGCTGCGGCGTACCGCTGATCGCCAACGGCTTTACCGATA
AAGCACGCAAACAGGCAATTACGAATGTAGAGTCGATCCGCGAAGCTGTGGGAGTAAAAGGCATTCCGGTGATTGCCACC
TCCTCAACCTGTACATTTGCCCTGCGCGACGAATACCCGGAAGTGCTGAATGTCGACAACAAAGGCTTGCGCGATCATAT
CGAACTGGCGACCCGCTGGCTGTGGCGCAAGCTGGACGAAGGCAAAACGTTACCGCTGAAACCGCTGCCGCTGAAAGTGG
TTTATCACACTCCGTGCCATATGGAAAAAATGGGCTGGACGCTCTACACCCTGGAGCTGTTGCGTAACATCCCGGGGCTT
GAGTTAACGGTGCTGGATTCCCAGTGCTGCGGTATTGCGGGTACTTACGGTTTCAAAAAAGAGAACTACCCCACCTCACA
AGCCATCGGCGCACCACTGTTCCGCCAGATAGAAGAAAGCGGCGCAGATCTGGTGGTCACCGACTGCGAAACCTGTAAAT
GGCAGATTGAGATGTCCACAAGTCTTCGCTGCGAACATCCGATTACGCTACTGGCCCAGGCGCTGGCTTAA

Upstream 100 bases:

>100_bases
GCGGATTTGATCCCATCGCCCAGGGATGCGGCGGCGGTGTTTGTGCCGTCAGTGCTTTACATGCCGCTCAACAGATTGCC
CAACGCGCAGGAGGCCAACA

Downstream 100 bases:

>100_bases
ACTCCTTTCTGATGCCCGGTAAGCATGTGGTTACCGGGCATTTTTGCGTACACGATTCCGTGCCCAATGTATGCGTTGCA
ACGCAGTGAAAATTCCTCTG

Product: sn-glycerol-3-phosphate dehydrogenase subunit C

Products: glycerone phosphate; reduced acceptor

Alternate protein names: G-3-P dehydrogenase

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRAR
AKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYK
DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIAT
SSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRNIPGL
ELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA

Sequences:

>Translated_396_residues
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRAR
AKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYK
DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIAT
SSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRNIPGL
ELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA
>Mature_396_residues
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRAR
AKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYK
DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIAT
SSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRNIPGL
ELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA

Specific function: Electron transfer protein; may also function as the membrane anchor for the glpAB dimer

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

Organism=Escherichia coli, GI1788576, Length=396, Percent_Identity=100, Blast_Score=825, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLPC_ECO57 (P0A997)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B85864
- PIR:   H91019
- RefSeq:   NP_288819.1
- RefSeq:   NP_311155.1
- ProteinModelPortal:   P0A997
- SMR:   P0A997
- EnsemblBacteria:   EBESCT00000024004
- EnsemblBacteria:   EBESCT00000058545
- GeneID:   916836
- GeneID:   959546
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z3501
- KEGG:   ecs:ECs3128
- GeneTree:   EBGT00050000011307
- HOGENOM:   HBG404065
- OMA:   MIPGLEL
- ProtClustDB:   PRK11168
- BioCyc:   ECOL83334:ECS3128-MONOMER
- GO:   GO:0006810
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR004017
- InterPro:   IPR012285
- InterPro:   IPR017753
- InterPro:   IPR009051
- Gene3D:   G3DSA:1.10.1060.10
- TIGRFAMs:   TIGR03379

Pfam domain/function: PF02754 CCG; SSF46548 Helical_ferredxn

EC number: 1.1.99.5

Molecular weight: Translated: 44108; Mature: 44108

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCK
CCCCCHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCC
RCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKP
CCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
VRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYKDQVAFFHGCFVNYNHPQLGK
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHH
DLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIAT
HHHHHHHHHCCCHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEE
SSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCH
CCCEEEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCC
MEKMGWTLYTLELLRNIPGLELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEES
HHHHCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHC
GADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA
CCCEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHC
>Mature Secondary Structure
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCK
CCCCCHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCC
RCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKP
CCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
VRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYKDQVAFFHGCFVNYNHPQLGK
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHH
DLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIAT
HHHHHHHHHCCCHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEE
SSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCH
CCCEEEEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCC
MEKMGWTLYTLELLRNIPGLELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEES
HHHHCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHC
GADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA
CCCEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: sn-glycerol 3-phosphate; acceptor

Specific reaction: sn-glycerol 3-phosphate + acceptor = glycerone phosphate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796