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The map label for this gene is rtcB [H]

Identifier: 209397766

GI number: 209397766

Start: 4372881

End: 4374107

Strand: Reverse

Name: rtcB [H]

Synonym: ECH74115_4729

Alternate gene names: 209397766

Gene position: 4374107-4372881 (Counterclockwise)

Preceding gene: 209398865

Following gene: 209399256

Centisome position: 78.5

GC content: 50.86

Gene sequence:

>1227_bases
ATGAATTACGAATTACTGACCACTGAAAATGCCCCGGTAAAAATGTGGACCAAAGGCGTGCCGGTAGAAGCCGATGCGCG
TCAGCAACTTATTAATACGGCGAAGATGCCGTTTATTTTCAAACATATTGCGGTAATGCCTGATGTACACCTGGGTAAAG
GTTCCACCATTGGTAGCGTGATCCCGACCAAAGGGGCGATTATTCCGGCGGCGGTGGGCGTGGATATTGGCTGTGGAATG
AACGCACTACGTACCGCTTTAACGGCGGCTGACCTGCCGGAAAACCTGGCGGAGCTGCGTCAGGCGATTGAAACTGCGGT
GCCGCACGGGCGTACCACTGGCCGTTGTAAACGTGATAAAGGCGCATGGGAAAACCCGCCTGTTAACGTCGATGCGAAAT
GGGCTGAGCTGGAGGCCGGTTATCAGTGGTTAACGCAAAAATATCCGCGTTTCCTTAACACTAACAACTATAAACACCTG
GGAACGCTGGGAACGGGTAACCACTTTATTGAAATCTGCCTTGATGAGTCGGACCAGGTGTGGATTATGCTGCACTCCGG
TTCACGCGGAATTGGTAATGCCATCGGGACTTACTTTATCGATCTGGCGCAAAAAGAGATGCAGGAAACGCTTGAAACAT
TGCCGTCGCGTGATCTGGCGTACTTTATGGAAGGTACGGAATACTTTGATGATTACCTGAAAGCCGTGGCCTGGGCGCAG
CTTTTTGCCAGCCTTAACCGCGATGTGATGATGGAAAACGTAGTAACGGCGTTGCAGAGCATTACGCAGAAAACGGTCAG
ACAGCCACAAACGCTGGCGATGGAAGAGATCAACTGTCACCACAACTATGTGCAAAAAGAACAGCACTTTGGTGAAGAGA
TCTACGTGACGCGTAAAGGCGCGGTGTCTGCGCGTGCTGGTCAATATGGAATTATTCCAGGGTCGATGGGAGCGAAAAGC
TTTATCGTCCGTGGGCTGGGAAATGAAGAGTCGTTCTGTTCGTGCAGCCACGGTGCCGGGCGGGTTATGAGCCGTACTAA
AGCGAAAAAAATGTTCAGCGTGGAAGATCAAATTCGTGCCACCGTGCATGTGGAATGCCGTAAAGATGCCGAAGTGATCG
ACGAAATCCCGATGGCGTATAAAGATATTGATGCGGTGATGGCGGCACAAAGCGATCTGGTGGAAGTTATCTACACCCTA
CGTCAGGTGGTGTGCGTAAAAGGATAA

Upstream 100 bases:

>100_bases
TTTTTAAAACAATGAATTAAAAAATTAATCTGCTTATTTAATTTTCTGGCACGACGGTTGCAATTATCAGGACCGCAAAC
AACGAAAAGAGAAAAACAAA

Downstream 100 bases:

>100_bases
ATGATGAAAAGGATGATTGCGCTGGATGGCGCACAGGGCGAAGGCGGCGGGCAGATCATGCGCTCGGCGCTGAGTCTGTC
GATGATAACCGGCCAGCCAT

Product: RtcB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MNYELLTTENAPVKMWTKGVPVEADARQQLINTAKMPFIFKHIAVMPDVHLGKGSTIGSVIPTKGAIIPAAVGVDIGCGM
NALRTALTAADLPENLAELRQAIETAVPHGRTTGRCKRDKGAWENPPVNVDAKWAELEAGYQWLTQKYPRFLNTNNYKHL
GTLGTGNHFIEICLDESDQVWIMLHSGSRGIGNAIGTYFIDLAQKEMQETLETLPSRDLAYFMEGTEYFDDYLKAVAWAQ
LFASLNRDVMMENVVTALQSITQKTVRQPQTLAMEEINCHHNYVQKEQHFGEEIYVTRKGAVSARAGQYGIIPGSMGAKS
FIVRGLGNEESFCSCSHGAGRVMSRTKAKKMFSVEDQIRATVHVECRKDAEVIDEIPMAYKDIDAVMAAQSDLVEVIYTL
RQVVCVKG

Sequences:

>Translated_408_residues
MNYELLTTENAPVKMWTKGVPVEADARQQLINTAKMPFIFKHIAVMPDVHLGKGSTIGSVIPTKGAIIPAAVGVDIGCGM
NALRTALTAADLPENLAELRQAIETAVPHGRTTGRCKRDKGAWENPPVNVDAKWAELEAGYQWLTQKYPRFLNTNNYKHL
GTLGTGNHFIEICLDESDQVWIMLHSGSRGIGNAIGTYFIDLAQKEMQETLETLPSRDLAYFMEGTEYFDDYLKAVAWAQ
LFASLNRDVMMENVVTALQSITQKTVRQPQTLAMEEINCHHNYVQKEQHFGEEIYVTRKGAVSARAGQYGIIPGSMGAKS
FIVRGLGNEESFCSCSHGAGRVMSRTKAKKMFSVEDQIRATVHVECRKDAEVIDEIPMAYKDIDAVMAAQSDLVEVIYTL
RQVVCVKG
>Mature_408_residues
MNYELLTTENAPVKMWTKGVPVEADARQQLINTAKMPFIFKHIAVMPDVHLGKGSTIGSVIPTKGAIIPAAVGVDIGCGM
NALRTALTAADLPENLAELRQAIETAVPHGRTTGRCKRDKGAWENPPVNVDAKWAELEAGYQWLTQKYPRFLNTNNYKHL
GTLGTGNHFIEICLDESDQVWIMLHSGSRGIGNAIGTYFIDLAQKEMQETLETLPSRDLAYFMEGTEYFDDYLKAVAWAQ
LFASLNRDVMMENVVTALQSITQKTVRQPQTLAMEEINCHHNYVQKEQHFGEEIYVTRKGAVSARAGQYGIIPGSMGAKS
FIVRGLGNEESFCSCSHGAGRVMSRTKAKKMFSVEDQIRATVHVECRKDAEVIDEIPMAYKDIDAVMAAQSDLVEVIYTL
RQVVCVKG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=446, Percent_Identity=28.6995515695067, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI2367224, Length=408, Percent_Identity=99.0196078431373, Blast_Score=850, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17506665, Length=444, Percent_Identity=25.9009009009009, Blast_Score=131, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24585217, Length=444, Percent_Identity=28.6036036036036, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 45238; Mature: 45238

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS01288 UPF0027

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYELLTTENAPVKMWTKGVPVEADARQQLINTAKMPFIFKHIAVMPDVHLGKGSTIGSV
CCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCC
IPTKGAIIPAAVGVDIGCGMNALRTALTAADLPENLAELRQAIETAVPHGRTTGRCKRDK
CCCCCCEEEHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GAWENPPVNVDAKWAELEAGYQWLTQKYPRFLNTNNYKHLGTLGTGNHFIEICLDESDQV
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCEEEEECCCCCEEEEEEECCCCCE
WIMLHSGSRGIGNAIGTYFIDLAQKEMQETLETLPSRDLAYFMEGTEYFDDYLKAVAWAQ
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LFASLNRDVMMENVVTALQSITQKTVRQPQTLAMEEINCHHNYVQKEQHFGEEIYVTRKG
HHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
AVSARAGQYGIIPGSMGAKSFIVRGLGNEESFCSCSHGAGRVMSRTKAKKMFSVEDQIRA
CCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHEE
TVHVECRKDAEVIDEIPMAYKDIDAVMAAQSDLVEVIYTLRQVVCVKG
EEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNYELLTTENAPVKMWTKGVPVEADARQQLINTAKMPFIFKHIAVMPDVHLGKGSTIGSV
CCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCC
IPTKGAIIPAAVGVDIGCGMNALRTALTAADLPENLAELRQAIETAVPHGRTTGRCKRDK
CCCCCCEEEHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GAWENPPVNVDAKWAELEAGYQWLTQKYPRFLNTNNYKHLGTLGTGNHFIEICLDESDQV
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCEEEEECCCCCEEEEEEECCCCCE
WIMLHSGSRGIGNAIGTYFIDLAQKEMQETLETLPSRDLAYFMEGTEYFDDYLKAVAWAQ
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LFASLNRDVMMENVVTALQSITQKTVRQPQTLAMEEINCHHNYVQKEQHFGEEIYVTRKG
HHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
AVSARAGQYGIIPGSMGAKSFIVRGLGNEESFCSCSHGAGRVMSRTKAKKMFSVEDQIRA
CCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHEE
TVHVECRKDAEVIDEIPMAYKDIDAVMAAQSDLVEVIYTLRQVVCVKG
EEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 9738023 [H]