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The map label for this gene is yrbB

Identifier: 209397627

GI number: 209397627

Start: 4181083

End: 4181376

Strand: Reverse

Name: yrbB

Synonym: ECH74115_4513

Alternate gene names: 209397627

Gene position: 4181376-4181083 (Counterclockwise)

Preceding gene: 209396690

Following gene: 209396580

Centisome position: 75.04

GC content: 53.4

Gene sequence:

>294_bases
ATGAGCGAGTCACTGAGCTGGATGCAGACGGGTGACACACTGGCGTTATCCGGAGAGCTGGATCAGGACGTTCTGCTACC
GCTTTGGGAAATGCGTGAGGAAGCGGTGAAGGGGATTACCTGCATCGATCTTAGCCGTGTGTCCCGCGTGGATACGGGTG
GACTGGCACTGCTGCTCCATCTTATCGATCTGGCGAAAAAGCAGGGCAACAACGTGACGCTTCAGGGGGTAAACGACAAA
GTGTATACCCTGGCGAAATTGTATAATTTGCCTGCTGATGTTCTGCCTCGTTAA

Upstream 100 bases:

>100_bases
ACGAGTGGGGAACGCTGCTACGTACCAAAGGTATCGACGGCCTGACTGCGCAACTGAAATCGATTTCTCAACAGAAAATC
ACTCTGGAAGAGAAAAAATA

Downstream 100 bases:

>100_bases
ATTTTTTCAGGCCGGATATGGCGTTAACCGCCTGTCCGGCAAACCTGCCTGCAAGTCGAGCCTTGTCTGATTTATCAGCG
AGGCTTTTTGCTTATTTATG

Product: YrbB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MSESLSWMQTGDTLALSGELDQDVLLPLWEMREEAVKGITCIDLSRVSRVDTGGLALLLHLIDLAKKQGNNVTLQGVNDK
VYTLAKLYNLPADVLPR

Sequences:

>Translated_97_residues
MSESLSWMQTGDTLALSGELDQDVLLPLWEMREEAVKGITCIDLSRVSRVDTGGLALLLHLIDLAKKQGNNVTLQGVNDK
VYTLAKLYNLPADVLPR
>Mature_96_residues
SESLSWMQTGDTLALSGELDQDVLLPLWEMREEAVKGITCIDLSRVSRVDTGGLALLLHLIDLAKKQGNNVTLQGVNDKV
YTLAKLYNLPADVLPR

Specific function: Part of the ABC transporter complex mlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner memb

COG id: COG3113

COG function: function code R; Predicted NTP binding protein (contains STAS domain)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain

Homologues:

Organism=Escherichia coli, GI87082227, Length=97, Percent_Identity=100, Blast_Score=195, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MLAB_ECOLI (P64602)

Other databases:

- EMBL:   U18997
- EMBL:   U00096
- EMBL:   AP009048
- RefSeq:   AP_003734.1
- RefSeq:   NP_417658.4
- ProteinModelPortal:   P64602
- SMR:   P64602
- DIP:   DIP-47898N
- STRING:   P64602
- EnsemblBacteria:   EBESCT00000003577
- EnsemblBacteria:   EBESCT00000017184
- GeneID:   947954
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5535
- KEGG:   eco:b3191
- EchoBASE:   EB2649
- EcoGene:   EG12797
- eggNOG:   COG3113
- GeneTree:   EBGT00050000009745
- HOGENOM:   HBG731225
- OMA:   MANALNW
- ProtClustDB:   CLSK2394893
- BioCyc:   EcoCyc:G7658-MONOMER
- Genevestigator:   P64602
- GO:   GO:0005737
- InterPro:   IPR002645
- Gene3D:   G3DSA:3.30.750.24

Pfam domain/function: PF01740 STAS; SSF52091 STAS

EC number: NA

Molecular weight: Translated: 10681; Mature: 10549

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESLSWMQTGDTLALSGELDQDVLLPLWEMREEAVKGITCIDLSRVSRVDTGGLALLLH
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHCCCCCHHHHHHH
LIDLAKKQGNNVTLQGVNDKVYTLAKLYNLPADVLPR
HHHHHHHCCCCEEEEECCCHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
SESLSWMQTGDTLALSGELDQDVLLPLWEMREEAVKGITCIDLSRVSRVDTGGLALLLH
CCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHCCCCCHHHHHHH
LIDLAKKQGNNVTLQGVNDKVYTLAKLYNLPADVLPR
HHHHHHHCCCCEEEEECCCHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503