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The map label for this gene is ygfU [H]

Identifier: 209397544

GI number: 209397544

Start: 3873785

End: 3875362

Strand: Direct

Name: ygfU [H]

Synonym: ECH74115_4177

Alternate gene names: 209397544

Gene position: 3873785-3875362 (Clockwise)

Preceding gene: 209396772

Following gene: 209397252

Centisome position: 69.52

GC content: 48.99

Gene sequence:

>1578_bases
TTGCCTCCGCAATTCCTGTCTCTAACTCCCCTTCCTCGCAAAAACTGGCACTCCACGAGCATGTGTTTAGACAGTTTCAT
TAACGTAAACGGTTGCTTTTTACTCTGGCGGGCGAAAGGAGAAACACTGATGAGCGCCATAGATTCCCAACTTCCCTCAT
CTTCTGGGCAAGACCGCCCAACTGATGAGGTTGACCGCATATTATCACCAGGAAAGCTGATCATACTCGGTCTGCAACAC
GTCCTTGTCATGTACGCAGGTGCAGTCGCTGTTCCTCTTATGATTGGTGACCGACTGGGCCTCTCAAAAGAAGCTATTGC
GATGCTCATTAGCTCGGATCTCTTTTGCTGCGGGATCGTCACATTATTGCAATGTATCGGTATCGGCCGCTTTATGGGGA
TCCGCCTGCCGGTGATTATGTCGGTGACCTTTGCTGCTGTAACACCAATGATAGCCATTGGGATGAACCCGGATATCGGC
CTGCTGGGTATATTTGGTGCCACTATCGCCGCGGGTTTTATCACCACATTATTAGCGCAACTTATCGGTCGCTTGATGCC
TTTATTCCCGCCACTGGTTACCGGTGTGGTTATTACTTCTATCGGGCTTAGCATCATTCAGGTGGGTATTGACTGGGCCG
CCGGAGGTAAAGGGAATCCGCAATATGGTAATCCCGTTTATTTAGGTATCTCCTTTGCCGTCTTAATTTTTATCTTGCTC
ATTACTCGCTATGCGAAAGGATTTATGTCCAACGTCGCCGTATTACTGGGGATTGTATTTGGCTTTTTACTTTCGTGGAT
GATGAATGAAGTCAATTTATCCGGGCTACATGATGCCTCGTGGTTTGCGATTGTCACCCCGATGTCGTTTGGTATGCCGA
TTTTCGATCCCGTTTCCATTCTGACCATGACTGCCGTGTTAATCATCGTGTTTATCGAGTCGATGGGGATGTTCCTGGCA
CTGGGTGAAATAGTCGGTCGTAAACTCTCTTCGCACGATATTATTCGCGGGCTGCGTGTCGATGGCGTAGGGACAATGAT
TGGTGGCACGTTTAACAGCTTCCCCCACACGTCATTTTCTCAAAACGTTGGCCTGGTTAGCGTGACGCGCGTTCATAGCC
GCTGGGTGTGTATTTCTTCGGGAATTATATTAATCCTGTTTGGCATGGTGCCAAAAATGGCGGTGCTGGTAGCCTCCATT
CCGCAATTTGTGCTGGGCGGCGCTGGTCTGGTGATGTTCGGCATGGTACTGGCGACAGGGATTCGAATTCTGTCGCGCTG
TAACTACACCACCAACCGTTACAACCTCTATATTGTGGCGATCAGTCTCGGCGTTGGCATGACTCCAACGCTCTCTCACG
ATTTCTTTTCTAAGTTACCGGCCGTACTGCAACCGCTGCTACATAGCGGCATTATGCTCGCAACCCTTAGCGCCGTTGTG
CTGAACGTCTTCTTTAATGGCTATCAGCATCATGCTGACCTGGTGAAGGAATCCGTCTCTGATAAAGATTTAAAAGTCAG
GACAGTACGTATGTGGCTTCTGATGCGCAAGCTGAAGAAAAATGAGCATGGAGAATAA

Upstream 100 bases:

>100_bases
CATGCCAGAATGATTAATGAAATATCAATATGAGAAAATTACAGATAATTCCATTGTCAGGTTCTCTTGTCATTTTCGTA
GTTTAAGCACGATTATGTGA

Downstream 100 bases:

>100_bases
TATGAATTTTTTAATGCGCGCTATATTCAGTCTGCTGTTGCTTTTTACTCTCTCTATTCCTGTCATTTCTGACTGTGTTG
CAATGGCCATTGAAAGTCGC

Product: putative xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 524

Protein sequence:

>525_residues
MPPQFLSLTPLPRKNWHSTSMCLDSFINVNGCFLLWRAKGETLMSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQH
VLVMYAGAVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIG
LLGIFGATIAAGFITTLLAQLIGRLMPLFPPLVTGVVITSIGLSIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILL
ITRYAKGFMSNVAVLLGIVFGFLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFLA
LGEIVGRKLSSHDIIRGLRVDGVGTMIGGTFNSFPHTSFSQNVGLVSVTRVHSRWVCISSGIILILFGMVPKMAVLVASI
PQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYNLYIVAISLGVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVV
LNVFFNGYQHHADLVKESVSDKDLKVRTVRMWLLMRKLKKNEHGE

Sequences:

>Translated_525_residues
MPPQFLSLTPLPRKNWHSTSMCLDSFINVNGCFLLWRAKGETLMSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQH
VLVMYAGAVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIG
LLGIFGATIAAGFITTLLAQLIGRLMPLFPPLVTGVVITSIGLSIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILL
ITRYAKGFMSNVAVLLGIVFGFLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFLA
LGEIVGRKLSSHDIIRGLRVDGVGTMIGGTFNSFPHTSFSQNVGLVSVTRVHSRWVCISSGIILILFGMVPKMAVLVASI
PQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYNLYIVAISLGVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVV
LNVFFNGYQHHADLVKESVSDKDLKVRTVRMWLLMRKLKKNEHGE
>Mature_524_residues
PPQFLSLTPLPRKNWHSTSMCLDSFINVNGCFLLWRAKGETLMSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHV
LVMYAGAVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIGL
LGIFGATIAAGFITTLLAQLIGRLMPLFPPLVTGVVITSIGLSIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILLI
TRYAKGFMSNVAVLLGIVFGFLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFLAL
GEIVGRKLSSHDIIRGLRVDGVGTMIGGTFNSFPHTSFSQNVGLVSVTRVHSRWVCISSGIILILFGMVPKMAVLVASIP
QFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYNLYIVAISLGVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVVL
NVFFNGYQHHADLVKESVSDKDLKVRTVRMWLLMRKLKKNEHGE

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=441, Percent_Identity=24.9433106575964, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI40316845, Length=441, Percent_Identity=24.9433106575964, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI44680145, Length=437, Percent_Identity=25.858123569794, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI44680143, Length=441, Percent_Identity=25.6235827664399, Blast_Score=107, Evalue=3e-23,
Organism=Escherichia coli, GI87082181, Length=482, Percent_Identity=99.7925311203319, Blast_Score=952, Evalue=0.0,
Organism=Escherichia coli, GI1790087, Length=460, Percent_Identity=28.695652173913, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI87082178, Length=465, Percent_Identity=26.4516129032258, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788843, Length=391, Percent_Identity=27.6214833759591, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI87081818, Length=457, Percent_Identity=25.8205689277899, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17558856, Length=472, Percent_Identity=23.5169491525424, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17541904, Length=463, Percent_Identity=21.5982721382289, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17542262, Length=450, Percent_Identity=22.8888888888889, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17542260, Length=238, Percent_Identity=27.3109243697479, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71993493, Length=238, Percent_Identity=26.890756302521, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356175, Length=427, Percent_Identity=24.1217798594848, Blast_Score=102, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 56723; Mature: 56592

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PPQFLSLTPLPRKNWHSTSMCLDSFINVNGCFLLWRAKGETLMSAIDSQLPSSSGQDRP
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCC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HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]