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The map label for this gene is tauA

Identifier: 209397536

GI number: 209397536

Start: 449833

End: 450795

Strand: Direct

Name: tauA

Synonym: ECH74115_0440

Alternate gene names: 209397536

Gene position: 449833-450795 (Clockwise)

Preceding gene: 209396745

Following gene: 209397710

Centisome position: 8.07

GC content: 56.07

Gene sequence:

>963_bases
ATGGCAATTTCATCGCGTAACACTCTTCTTGCCGCACTGGCATTCATCGCTTTTCAGGCGCAGGCGGTGAACGTCACCGT
GGCGTATCAAACCTCAGCCGAACCGGCGAAAGTGGCTCAGGCCGATAACACCTTTGCTAAAGAAAGTGGAGCAACTGTGG
ACTGGCGCAAGTTTGACAGCGGAGCCAGCATCGTGCGGGCGCTGGCTTCTGGCGACGTGCAAATCGGCAACCTTGGTTCC
AGCCCGTTAGCGGTTGCAGCCAGCCAACAGGTGCCGATTGAAGTCTTCTTGCTGGCGTCAAAACTGGGTAACTCCGAAGC
GCTGGTGGTAAAGAAAACTATCAGCAAACCGGAAGATCTGATTGGCAAACGCATCGCCGTACCGTTTATCTCCACCACCC
ACTACAGCCTGCTGGCGGCGCTGAAACACTGGGGCATTAAACCCGGGCAAGTGGAGATTGTGAACCTGCAGCCGCCCGCG
ATTATCGCTGCCTGGCAGCGGGGAGATATTGATGGTGCTTATGTCTGGGCACCGGCGGTTAACGCCCTGGAAAAAGACGG
CAAGGTGTTGACCGATTCTGAACAGGTCGGGCAGTGGGGCGCGCCAACGCTGGACGTTTGGGTGGTGCGCAAAGATTTTG
CCGAGAAACATCCTGAGGTCGTGAAAGCGTTCGCTAAAAGCGCCATCGATGCTCAGCAACCGTACATTGCTAACCCAGAC
GTGTGGCTGAAACAGCCGGAAAACATCAGCAAACTGGCGCGTTTAAGCGGCGTGCCTGAAGGTGACGTTCCGGGGCTGGT
GAAGGGGAATACCTATCTGACGCCGCAGCAACAAACGGCAGAACTGACCGGACCGGTGAACAAAGCGATCATCGACACCG
CGCAGTTTTTGAAAGAGCAGGGCAAGGTCCCGGCTGTAGCGAATGATTACAGCCAGTACGTTACCTCGCGCTTCGTGCAA
TAA

Upstream 100 bases:

>100_bases
TCTAAAAACGCTTTGTTCTTAACAAGACCTTTTAATTCCTTTATCAAACTGACCCGCAACGAAATACTGCTCCCATAACA
AGACAGGGGAGCAGACAATC

Downstream 100 bases:

>100_bases
AAGGAGGCGCAGATGCTGCAAATCTCTCATCTTTACGCCGATTATGGCGGCAAACCGGTACTGGAAGATATCAACCTGAC
GCTGGAAAGCGGCGAGCTAC

Product: taurine transporter substrate binding subunit

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: Sulfate starvation-induced protein 1; SSI1

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNTFAKESGATVDWRKFDSGASIVRALASGDVQIGNLGS
SPLAVAASQQVPIEVFLLASKLGNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPA
IIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHPEVVKAFAKSAIDAQQPYIANPD
VWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQQQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ

Sequences:

>Translated_320_residues
MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNTFAKESGATVDWRKFDSGASIVRALASGDVQIGNLGS
SPLAVAASQQVPIEVFLLASKLGNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPA
IIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHPEVVKAFAKSAIDAQQPYIANPD
VWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQQQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ
>Mature_319_residues
AISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNTFAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSS
PLAVAASQQVPIEVFLLASKLGNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPAI
IAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHPEVVKAFAKSAIDAQQPYIANPDV
WLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQQQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ

Specific function: Part of a binding-protein-dependent transport system for taurine

COG id: COG4521

COG function: function code P; ABC-type taurine transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein ssuA/tauA family

Homologues:

Organism=Escherichia coli, GI87081727, Length=320, Percent_Identity=100, Blast_Score=642, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAUA_ECOLI (Q47537)

Other databases:

- EMBL:   D85613
- EMBL:   U73857
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   S78604
- RefSeq:   AP_001016.1
- RefSeq:   NP_414899.2
- ProteinModelPortal:   Q47537
- IntAct:   Q47537
- STRING:   Q47537
- EnsemblBacteria:   EBESCT00000004675
- EnsemblBacteria:   EBESCT00000014942
- GeneID:   945030
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW0357
- KEGG:   eco:b0365
- EchoBASE:   EB3085
- EcoGene:   EG13300
- eggNOG:   COG4521
- GeneTree:   EBGT00050000010032
- HOGENOM:   HBG566818
- OMA:   LLQGNVY
- ProtClustDB:   PRK11480
- BioCyc:   EcoCyc:TAUA-MONOMER
- Genevestigator:   Q47537
- InterPro:   IPR007210
- InterPro:   IPR001638
- InterPro:   IPR010068
- SMART:   SM00062
- TIGRFAMs:   TIGR01729

Pfam domain/function: PF04069 OpuAC

EC number: NA

Molecular weight: Translated: 34266; Mature: 34135

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNTFAKESGATVDWRKFDS
CCCCCCHHHHHHHHHHHHHCEEEEEEEEEECCCCCHHHHHCCCCHHHCCCCEEEHHCCCC
GASIVRALASGDVQIGNLGSSPLAVAASQQVPIEVFLLASKLGNSEALVVKKTISKPEDL
HHHHHHHHHCCCEEECCCCCCCEEEEECCCCCEEEEEEEHHCCCCCEEEEEHHHCCCHHH
IGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPAIIAAWQRGDIDGAYVWAPAV
HCCEEEEEEECHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCCCCEEEECHHH
NALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHPEVVKAFAKSAIDAQQPYIANPD
HHHHHCCCEEECHHHHCCCCCCCEEEEEEEHHHHHCCHHHHHHHHHHHHCCCCCEECCCC
VWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQQQTAELTGPVNKAIIDTAQFLKEQ
CEECCCCCHHHHHHHCCCCCCCCCCEEECCEEECCCHHHHHHCCCHHHHHHHHHHHHHHC
GKVPAVANDYSQYVTSRFVQ
CCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNTFAKESGATVDWRKFDS
CCCCCHHHHHHHHHHHHHCEEEEEEEEEECCCCCHHHHHCCCCHHHCCCCEEEHHCCCC
GASIVRALASGDVQIGNLGSSPLAVAASQQVPIEVFLLASKLGNSEALVVKKTISKPEDL
HHHHHHHHHCCCEEECCCCCCCEEEEECCCCCEEEEEEEHHCCCCCEEEEEHHHCCCHHH
IGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPAIIAAWQRGDIDGAYVWAPAV
HCCEEEEEEECHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEECCCCCCCEEEECHHH
NALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHPEVVKAFAKSAIDAQQPYIANPD
HHHHHCCCEEECHHHHCCCCCCCEEEEEEEHHHHHCCHHHHHHHHHHHHCCCCCEECCCC
VWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQQQTAELTGPVNKAIIDTAQFLKEQ
CEECCCCCHHHHHHHCCCCCCCCCCEEECCEEECCCHHHHHHCCCHHHHHHHHHHHHHHC
GKVPAVANDYSQYVTSRFVQ
CCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 8774726