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The map label for this gene is fucR [H]

Identifier: 209397462

GI number: 209397462

Start: 3766165

End: 3766896

Strand: Direct

Name: fucR [H]

Synonym: ECH74115_4069

Alternate gene names: 209397462

Gene position: 3766165-3766896 (Clockwise)

Preceding gene: 209396564

Following gene: 209397968

Centisome position: 67.59

GC content: 47.95

Gene sequence:

>732_bases
ATGAAAGCGGCACGCCAGCAAGCGATAGTCGACCTGCTGCTGAACCATACCAGCCTGACCACGGAAGCTCTCTCTGAACA
GCTAAAGGTCAGTAAAGAAACCATTCGTCGCGATCTCAATGAATTACAGACGCAGGGTAAAATTCTGCGCAATCATGGAC
GCGCTAAATATATCCACCGTCAAAATCAAGACAGTGGCGATCCCTTTCACATCAGGCTGAAAAGCCATTATGCGCATAAA
GCAGATATCGCGCGCGAGGCGCTCGCGTGGATTGAAGAAGGGATGGTGATAGCCTTAGACGCCAGTTCAACTTGCTGGTA
TCTGGCACGCCAGTTGCCTGACATCAACATTCAGGTCTTCACCAATAGCCATCCGATTTGCCATGAACTCGGTAAACGCG
AACGCATTCAACTGATCAGTTCCGGCGGCACACTTGAGCGCAAATATGGCTGTTACGTCAATCCCTCGCTGATTTCCCAA
CTTAAATCGCTGGAAATCGATCTGTTTATTTTTTCTTGTGAAGGGATCGATAGCAGCGGCGCACTGTGGGACTCCAATGC
TATCAACGCTGATTACAAATCAATGCTATTAAAACGCGCCGCGCAATCGTTGTTATTGATTGATAAAAGTAAATTTAATC
GTTCAGGGGAAGCCCGCATCGGGCATCTGGATGAGGTAACGCACATTATTTCTGATGAACGCCAGGTTGCAACTTCTTTG
GTAACAGGCTGA

Upstream 100 bases:

>100_bases
GAAGTACGGGAATATTCTTTTAAAAAAAGGGGTAACACCGTAATCTCATACCGGTACGCCCGCATGACGCGGGCGGTTAT
CGAATGATGGGGTGAAAAAT

Downstream 100 bases:

>100_bases
CGGAAAGGGTAGCAGGCCGGAGACGACGCCCCGGCCTTGCCTGTTATCGCTCGTCGCGACGACCACCCACCGCAGCCCAG
ATACGGCGGACGTGCACCGT

Product: DNA-binding transcriptional activator FucR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHK
ADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVFTNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQ
LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVATSL
VTG

Sequences:

>Translated_243_residues
MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHK
ADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVFTNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQ
LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVATSL
VTG
>Mature_243_residues
MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHK
ADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVFTNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQ
LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVATSL
VTG

Specific function: Transcriptional activator of the fuc operon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789170, Length=243, Percent_Identity=99.5884773662551, Blast_Score=499, Evalue=1e-143,
Organism=Escherichia coli, GI1788069, Length=231, Percent_Identity=32.9004329004329, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789829, Length=232, Percent_Identity=28.448275862069, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI87082344, Length=230, Percent_Identity=28.695652173913, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787540, Length=240, Percent_Identity=25.4166666666667, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789059, Length=231, Percent_Identity=27.7056277056277, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790753, Length=229, Percent_Identity=23.5807860262009, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1789519, Length=239, Percent_Identity=27.6150627615063, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790635, Length=231, Percent_Identity=23.8095238095238, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI226510968, Length=238, Percent_Identity=26.0504201680672, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27348; Mature: 27348

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHCC
QNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVF
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCEEEEE
TNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQLKSLEIDLFIFSCEGIDSSG
ECCCCHHHHHCCHHEEEEEECCCCEEECCCCEECHHHHHHHHHCEEEEEEEEECCCCCCC
ALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVATSL
CEECCCCCCHHHHHHHHHHHHHHHEEEEHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHH
VTG
CCC
>Mature Secondary Structure
MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHCC
QNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVF
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCEEEEE
TNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQLKSLEIDLFIFSCEGIDSSG
ECCCCHHHHHCCHHEEEEEECCCCEEECCCCEECHHHHHHHHHCEEEEEEEEECCCCCCC
ALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVATSL
CEECCCCCCHHHHHHHHHHHHHHHEEEEHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHH
VTG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503 [H]