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The map label for this gene is yniA

Identifier: 209397430

GI number: 209397430

Start: 2313804

End: 2314664

Strand: Direct

Name: yniA

Synonym: ECH74115_2443

Alternate gene names: 209397430

Gene position: 2313804-2314664 (Clockwise)

Preceding gene: 209396496

Following gene: 209396268

Centisome position: 41.52

GC content: 51.92

Gene sequence:

>861_bases
ATGTGGCAGGCAATCAGTCGTCTTTTGAGCGAGCAGTTAGGTGAAGGCGAAATCGAACTGCGTAATGAACTGCCTGGCGG
AGAAGTCCATGCCGCATGGCATTTGCGCTATGCAGGACATGACTTTTTCGTCAAATGTGATGAAAGGGAACTGCTTCCCG
GTTTTACCGCCGAAGCCGACCAACTGGAGTTACTGTCGCGTAGTAAAACCGTCACCGTGCCTAAGGTTTGGGCAGTTGGC
GCTGACCGTGACTACAGTTTTCTGGTGATGGATTATCTCCCACCTCGTCCGCTGGATGCGCATAGCGCATTTATTCTTGG
TCAGCAAATTGCGCGTTTACATCAATGGAGCGACCAACCACAATTTGGACTCGATTTTGATAACTCGCTCTCCACAACTC
CACAGCCCAACACCTGGCAACGTCGCTGGTCAACGTTTTTTGCTGAACAACGGATTGGCTGGCAGTTGGAACTGGCAGCA
GAAAAAGGGATCGCTTTCGGCAATATCGATGCCATCGTCGAGCATATTCAGCAGCGTCTCGCCTCACATCAACCGCAGCC
TTCTCTGTTGCACGGCGATTTATGGTCCGGCAACTGTGCGCTGGGTCCGGATGGCCCGTACATTTTCGACCCGGCCTGCT
ACTGGGGTGACCGAGAGTGCGACCTGGCGATGTTACCGCTGCATACTGAACAGCCGCCACAAATCTATGACGGCTATCAG
TCAGTATCCCCGCTACCTGCCGATTTCCTTGAACGTCAACCGGTTTACCAACTCTACACGCTGTTAAATCGTGCAAGATT
ATTTGGCGGTCAGCATTTGGTTATTGCTCAGCAGTCACTGGATAGATTATTAGCTGCGTGA

Upstream 100 bases:

>100_bases
TTTTGGGCAATAATCAGTCTGTGGTGTGCGTTAGCTCGTGTTTTTACACCGCATTCTTGCGCTAACCTTATGATCTGGCA
GACAACATGGGAGAGACATC

Downstream 100 bases:

>100_bases
TATGGGTTGAAGATAATGGCCGCTCCGTGCGGCCTTTTGATTAAATAAACCCAAGCAGAGAAAAGAACACATAACCTGCA
GCAATACAAATAACCGGCAG

Product: fructosamine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MWQAISRLLSEQLGEGEIELRNELPGGEVHAAWHLRYAGHDFFVKCDERELLPGFTAEADQLELLSRSKTVTVPKVWAVG
ADRDYSFLVMDYLPPRPLDAHSAFILGQQIARLHQWSDQPQFGLDFDNSLSTTPQPNTWQRRWSTFFAEQRIGWQLELAA
EKGIAFGNIDAIVEHIQQRLASHQPQPSLLHGDLWSGNCALGPDGPYIFDPACYWGDRECDLAMLPLHTEQPPQIYDGYQ
SVSPLPADFLERQPVYQLYTLLNRARLFGGQHLVIAQQSLDRLLAA

Sequences:

>Translated_286_residues
MWQAISRLLSEQLGEGEIELRNELPGGEVHAAWHLRYAGHDFFVKCDERELLPGFTAEADQLELLSRSKTVTVPKVWAVG
ADRDYSFLVMDYLPPRPLDAHSAFILGQQIARLHQWSDQPQFGLDFDNSLSTTPQPNTWQRRWSTFFAEQRIGWQLELAA
EKGIAFGNIDAIVEHIQQRLASHQPQPSLLHGDLWSGNCALGPDGPYIFDPACYWGDRECDLAMLPLHTEQPPQIYDGYQ
SVSPLPADFLERQPVYQLYTLLNRARLFGGQHLVIAQQSLDRLLAA
>Mature_286_residues
MWQAISRLLSEQLGEGEIELRNELPGGEVHAAWHLRYAGHDFFVKCDERELLPGFTAEADQLELLSRSKTVTVPKVWAVG
ADRDYSFLVMDYLPPRPLDAHSAFILGQQIARLHQWSDQPQFGLDFDNSLSTTPQPNTWQRRWSTFFAEQRIGWQLELAA
EKGIAFGNIDAIVEHIQQRLASHQPQPSLLHGDLWSGNCALGPDGPYIFDPACYWGDRECDLAMLPLHTEQPPQIYDGYQ
SVSPLPADFLERQPVYQLYTLLNRARLFGGQHLVIAQQSLDRLLAA

Specific function: Unknown

COG id: COG3001

COG function: function code G; Fructosamine-3-kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fructosamine kinase family

Homologues:

Organism=Homo sapiens, GI20149680, Length=294, Percent_Identity=28.9115646258503, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI11545906, Length=272, Percent_Identity=29.7794117647059, Blast_Score=99, Evalue=5e-21,
Organism=Escherichia coli, GI1788019, Length=286, Percent_Identity=99.6503496503496, Blast_Score=586, Evalue=1e-169,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YNIA_ECO57 (P58065)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   C85781
- PIR:   G90932
- RefSeq:   NP_288158.1
- RefSeq:   NP_310458.1
- ProteinModelPortal:   P58065
- SMR:   P58065
- EnsemblBacteria:   EBESCT00000026765
- EnsemblBacteria:   EBESCT00000058303
- GeneID:   913778
- GeneID:   961695
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z2754
- KEGG:   ecs:ECs2431
- GeneTree:   EBGT00050000011724
- HOGENOM:   HBG635091
- OMA:   LYNLYHI
- ProtClustDB:   CLSK880174
- BioCyc:   ECOL83334:ECS2431-MONOMER
- InterPro:   IPR016477
- InterPro:   IPR011009
- PIRSF:   PIRSF006221

Pfam domain/function: PF03881 Fructosamin_kin; SSF56112 Kinase_like

EC number: NA

Molecular weight: Translated: 32475; Mature: 32475

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWQAISRLLSEQLGEGEIELRNELPGGEVHAAWHLRYAGHDFFVKCDERELLPGFTAEAD
CHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEEEEECCEEEEEECCCCCCCCCCCCHH
QLELLSRSKTVTVPKVWAVGADRDYSFLVMDYLPPRPLDAHSAFILGQQIARLHQWSDQP
HHHHHHCCCEEECCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
QFGLDFDNSLSTTPQPNTWQRRWSTFFAEQRIGWQLELAAEKGIAFGNIDAIVEHIQQRL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEHHCCCCCCCHHHHHHHHHHHH
ASHQPQPSLLHGDLWSGNCALGPDGPYIFDPACYWGDRECDLAMLPLHTEQPPQIYDGYQ
HHCCCCCCEEECCCCCCCCCCCCCCCEEECCHHCCCCCCCCEEEECCCCCCCCHHHCCHH
SVSPLPADFLERQPVYQLYTLLNRARLFGGQHLVIAQQSLDRLLAA
HCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCC
>Mature Secondary Structure
MWQAISRLLSEQLGEGEIELRNELPGGEVHAAWHLRYAGHDFFVKCDERELLPGFTAEAD
CHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEEEEECCEEEEEECCCCCCCCCCCCHH
QLELLSRSKTVTVPKVWAVGADRDYSFLVMDYLPPRPLDAHSAFILGQQIARLHQWSDQP
HHHHHHCCCEEECCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
QFGLDFDNSLSTTPQPNTWQRRWSTFFAEQRIGWQLELAAEKGIAFGNIDAIVEHIQQRL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEEHHCCCCCCCHHHHHHHHHHHH
ASHQPQPSLLHGDLWSGNCALGPDGPYIFDPACYWGDRECDLAMLPLHTEQPPQIYDGYQ
HHCCCCCCEEECCCCCCCCCCCCCCCEEECCHHCCCCCCCCEEEECCCCCCCCHHHCCHH
SVSPLPADFLERQPVYQLYTLLNRARLFGGQHLVIAQQSLDRLLAA
HCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796