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The map label for this gene is rtn [H]

Identifier: 209397294

GI number: 209397294

Start: 3047081

End: 3048574

Strand: Direct

Name: rtn [H]

Synonym: ECH74115_3314

Alternate gene names: 209397294

Gene position: 3047081-3048574 (Clockwise)

Preceding gene: 209398438

Following gene: 209399185

Centisome position: 54.68

GC content: 50.6

Gene sequence:

>1494_bases
ATGATTGCGATACTGGTGAGCTGCCTTCAGTTTTTAGTGGCCTGGCATAAGCACGAAGTCAAATACGACACACTGATTAC
CGACGTACAAAAGTATCTCGATACCTATTTTGCCGACCTGAAATCCACTACTGACCGGCTCCAGCCGCTGACCTTAGATA
CATGCAAGCAAGCTAACCCCGAACTGACCGCCCGCGCGGCGTTTAGCATGAATGTCCGAACGTTTGTGCTGGTGAAAGAT
AAAAAAACATTCTGTTCATCTGCGACCGGTGAGATGGACATTCCACTCAATGAATTGATTCCTGCGCTCGACATTAATAA
AAATGTCGATATGGCGATCTTACCCGGCACGCCGATGGTGCCGAACAAACCCGCAATCGTCATCTGGTATCGCAACCCTT
TGCTGAAAAATAGCGGCGTCTTTGCCGCTCTGAATCTCAACCTGACGCCTTCTCTCTTTTATAGCTCACGGCAGGAAGAT
TACGATGGCGTCGCCCTCATTATTGGCAATACTGCGCTATCTACCTTTTCTTCACGTTTGATGAACGTTAACGAATTAAC
CGACATGCCAGTCCGTGAAACTAAAATTGCGGGCATTCCTCTGACCGTTCGGCTTTATGCAGATGACTGGACATGGAACG
ATGTGTGGTACGCATTTTTACTGGGCGGCATGAGTGGAACTGTCGTTGGCCTGCTCTGCTATTACCTGATGAGCGTACGT
ATGCGCCCCGGCAGAGAAATCATGACCGCCATCAAGCGCGAACAATTTTACGTGGCGTATCAACCGGTGGTGGATACACA
AGCTTTGCGAGTAACGGGCCTGGAAGTACTGCTACGCTGGCGGCATCCTGTCGCGGGAGAAATTCCCCCGGATGCCTTCA
TTAACTTTGCCGAATCGCAAAAGATGATTGTGCCGCTGACTCAGCACCTGTTTGAGTTAATTGCCCGCGATGCCGCAGAA
TTAGAAAAAGTGCTGCCGGTAGGCGTCAAATTTGGCATTAACATTGCGCCGGACCATCTGCACAGCGAAAGCTTTAAAGC
AAATATCCAGAAACTGCTCACTTCCCTACCCGCACACCATTTCCAGATTGTGCTGGAAATTACCGAGCGCGATATGCTGA
AAGAGCAAGAAGCCACACAACTCTTCGCCTGGCTGCACTCGGTCGGCGTAGAAATTGCTATTGATGACTTCGGCACCGGG
CACAGCGCGCTTATCTATCTTGAGCGTTTTACGCTCGATTATCTGAAAATTGACCGTGGATTTATCAACGCCATCGGTAC
GGAAACGATCACTTCACCCGTACTTGACGCGGTGCTGACGCTGGCGAAACGCCTCAATATGCTGACGGTTGCTGAGGGGG
TCGAAACGCCGGAACAGGCGCGATGGCTAAGCGAACGCGGCGTTAATTTCATGCAAGGCTACTGGATTAGTCGCCCGTTA
CCGCTGGACGATTTTGTCCGCTGGCTGAAGAAACCGTATACGCCGCAGTGGTAA

Upstream 100 bases:

>100_bases
TTAAATGTTGTCGTAATTTCAGGAAATTAACGGAATCATGTTCATACGCGCTCCCAATTCTGGACGTAAGCTCCTGCTTA
CCTGCATTGTTGCAGGCGTA

Downstream 100 bases:

>100_bases
GGTGTGCTTACGTCCCTTATTATTCATAGTGAAAGCATGCCGGATTGCGGCTAATGATGAGTAAAAGGAAATCCGTTGCA
GATGATTGTGCGCATACTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCKQANPELTARAAFSMNVRTFVLVKD
KKTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSGVFAALNLNLTPSLFYSSRQED
YDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAFLLGGMSGTVVGLLCYYLMSVR
MRPGREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAESQKMIVPLTQHLFELIARDAAE
LEKVLPVGVKFGINIAPDHLHSESFKANIQKLLTSLPAHHFQIVLEITERDMLKEQEATQLFAWLHSVGVEIAIDDFGTG
HSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVNFMQGYWISRPL
PLDDFVRWLKKPYTPQW

Sequences:

>Translated_497_residues
MIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCKQANPELTARAAFSMNVRTFVLVKD
KKTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSGVFAALNLNLTPSLFYSSRQED
YDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAFLLGGMSGTVVGLLCYYLMSVR
MRPGREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAESQKMIVPLTQHLFELIARDAAE
LEKVLPVGVKFGINIAPDHLHSESFKANIQKLLTSLPAHHFQIVLEITERDMLKEQEATQLFAWLHSVGVEIAIDDFGTG
HSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVNFMQGYWISRPL
PLDDFVRWLKKPYTPQW
>Mature_497_residues
MIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCKQANPELTARAAFSMNVRTFVLVKD
KKTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSGVFAALNLNLTPSLFYSSRQED
YDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAFLLGGMSGTVVGLLCYYLMSVR
MRPGREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAESQKMIVPLTQHLFELIARDAAE
LEKVLPVGVKFGINIAPDHLHSESFKANIQKLLTSLPAHHFQIVLEITERDMLKEQEATQLFAWLHSVGVEIAIDDFGTG
HSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVNFMQGYWISRPL
PLDDFVRWLKKPYTPQW

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=497, Percent_Identity=99.5975855130785, Blast_Score=1023, Evalue=0.0,
Organism=Escherichia coli, GI87081980, Length=474, Percent_Identity=30.8016877637131, Blast_Score=221, Evalue=8e-59,
Organism=Escherichia coli, GI87081845, Length=252, Percent_Identity=39.2857142857143, Blast_Score=178, Evalue=8e-46,
Organism=Escherichia coli, GI1786507, Length=247, Percent_Identity=36.8421052631579, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1790496, Length=251, Percent_Identity=30.6772908366534, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI87081743, Length=270, Percent_Identity=31.4814814814815, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1787541, Length=246, Percent_Identity=30.4878048780488, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081921, Length=255, Percent_Identity=29.8039215686275, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI226510982, Length=253, Percent_Identity=30.8300395256917, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788849, Length=244, Percent_Identity=28.6885245901639, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI87082096, Length=243, Percent_Identity=30.0411522633745, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1787055, Length=251, Percent_Identity=29.0836653386454, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787410, Length=227, Percent_Identity=25.9911894273128, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 56286; Mature: 56286

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCKQANP
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
ELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMV
CEEEEEEEEECCEEEEEEECCHHHHCCCCCCCCCCHHHCCCCCCCCCCCCEEEECCCCCC
PNKPAIVIWYRNPLLKNSGVFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRL
CCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHCCCCCCCCCEEEEECCHHHHHHHHHH
MNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAFLLGGMSGTVVGLLCYYLMSVR
CCHHHHCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHC
MRPGREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAESQ
CCCCHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCC
KMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPDHLHSESFKANIQKLLTSLPAHH
CEEEHHHHHHHHHHHHHHHHHHHHCCCCEEECCEECCHHHCHHHHHHHHHHHHHHCCCCC
FQIVLEITERDMLKEQEATQLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRG
EEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEHHHHHHHHHCCH
FINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVNFMQGYWISRPL
HHHHHCHHHHHHHHHHHHHHHHHHCCHHEECCCCCCHHHHHHHHHCCCHHHHCCCCCCCC
PLDDFVRWLKKPYTPQW
CHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCKQANP
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
ELTARAAFSMNVRTFVLVKDKKTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMV
CEEEEEEEEECCEEEEEEECCHHHHCCCCCCCCCCHHHCCCCCCCCCCCCEEEECCCCCC
PNKPAIVIWYRNPLLKNSGVFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRL
CCCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHCCCCCCCCCEEEEECCHHHHHHHHHH
MNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAFLLGGMSGTVVGLLCYYLMSVR
CCHHHHCCCCCCCCEECCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHC
MRPGREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAESQ
CCCCHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCC
KMIVPLTQHLFELIARDAAELEKVLPVGVKFGINIAPDHLHSESFKANIQKLLTSLPAHH
CEEEHHHHHHHHHHHHHHHHHHHHCCCCEEECCEECCHHHCHHHHHHHHHHHHHHCCCCC
FQIVLEITERDMLKEQEATQLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRG
EEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEHHHHHHHHHCCH
FINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVNFMQGYWISRPL
HHHHHCHHHHHHHHHHHHHHHHHHCCHHEECCCCCCHHHHHHHHHCCCHHHHCCCCCCCC
PLDDFVRWLKKPYTPQW
CHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]