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The map label for this gene is insK [C]

Identifier: 209397183

GI number: 209397183

Start: 2509893

End: 2510582

Strand: Reverse

Name: insK [C]

Synonym: ECH74115_2665

Alternate gene names: 209397183

Gene position: 2510582-2509893 (Counterclockwise)

Preceding gene: 209396455

Following gene: 209396099

Centisome position: 45.06

GC content: 54.06

Gene sequence:

>690_bases
ATGCCGCTGCTGGATAAGCTGCGTGAGCAGTACGGGGTCGGACCGGTATGCAGTGAACTGCATATTGCCCCGTCAACGTA
TTACCACTGTCAGCAACAGCGACATCATCCGGATAAACGCAGTGCCCGTGCGCAGCGCGATGACTGGCTGAAGAGAGAGA
TACAGCGCGTATACGATGAAAATCATCAGGTGTACGGTGTGCGTAAAGTCTGGCGCCAGTTGTTACGCGAAGGTATCAGG
GTGGCCAGATGTACAGTGGCGCGCCTCATGGCGGTTATGGGACTTGCCGGTGTTCTCCGGGGTAAAAAGGTCCGTACTAC
CGTCAGCCGGAAAGCCGTTTCCGCAGGCGACCGCGTAAACCGTCAGTTCGTGGCAGAACGTCCTGACCAGCTGTGGGTGG
CTGATTTTACTTACGTCAGCACATGGCAGGGCTTCGTCTATGTGGCGTTCATCATTGATGTGTTTTCCGGATGTATCGTG
GGGTGGCGAGTCTCATCGTCTATGGAAACGACATTCGTGCTGGATGCACTGGAGCAGGCGTTGTGGGCCCGTCGGCCGTC
CGGCACAGTCCATCACAGTGATAAAGGTTCTCAGTATGTATCACTGGCCTATACGGAGCGACTAAAAGAAGCAAAACTGC
TGGCATCAACAGGGAGTACAGGTGACTCGTATGACAATGTATTTTATTAG

Upstream 100 bases:

>100_bases
TGGAACGTGAAAATCGTGAACTGCGCCGCAGTAACGATATCCTTCGCCAGGCTTCCGCTTATTTTGCGAAGGCGGAGTTC
GACCGCCTCTGGAAAAAATA

Downstream 100 bases:

>100_bases
TTCACATACAATTATCAGATTATTCTGGGAATAAGGTCTGAATATTCTTTTTTATTTTATAAAAATTGCATTCAACTCCG
CTAGGCTGATTAGCCTGGTA

Product: transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKREIQRVYDENHQVYGVRKVWRQLLREGIR
VARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVSAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFSGCIV
GWRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYVSLAYTERLKEAKLLASTGSTGDSYDNVFY

Sequences:

>Translated_229_residues
MPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKREIQRVYDENHQVYGVRKVWRQLLREGIR
VARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVSAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFSGCIV
GWRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYVSLAYTERLKEAKLLASTGSTGDSYDNVFY
>Mature_228_residues
PLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKREIQRVYDENHQVYGVRKVWRQLLREGIRV
ARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVSAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFSGCIVG
WRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYVSLAYTERLKEAKLLASTGSTGDSYDNVFY

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=223, Percent_Identity=52.4663677130045, Blast_Score=229, Evalue=2e-60,
Organism=Escherichia coli, GI1789981, Length=227, Percent_Identity=29.5154185022026, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788405, Length=236, Percent_Identity=28.8135593220339, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1787263, Length=236, Percent_Identity=28.8135593220339, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1786753, Length=236, Percent_Identity=28.8135593220339, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1786570, Length=236, Percent_Identity=28.8135593220339, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1786490, Length=236, Percent_Identity=28.8135593220339, Blast_Score=101, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 26232; Mature: 26101

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKREIQRVYDE
CCHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
NHQVYGVRKVWRQLLREGIRVARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVSAGDRVN
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHH
RQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFSGCIVGWRVSSSMETTFVLDALEQA
HHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHH
LWARRPSGTVHHSDKGSQYVSLAYTERLKEAKLLASTGSTGDSYDNVFY
HHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKREIQRVYDE
CHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
NHQVYGVRKVWRQLLREGIRVARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVSAGDRVN
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHH
RQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFSGCIVGWRVSSSMETTFVLDALEQA
HHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHH
LWARRPSGTVHHSDKGSQYVSLAYTERLKEAKLLASTGSTGDSYDNVFY
HHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]