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The map label for this gene is ydhP

Identifier: 209397024

GI number: 209397024

Start: 2242127

End: 2243296

Strand: Reverse

Name: ydhP

Synonym: ECH74115_2369

Alternate gene names: 209397024

Gene position: 2243296-2242127 (Counterclockwise)

Preceding gene: 209398936

Following gene: 209398586

Centisome position: 40.26

GC content: 53.59

Gene sequence:

>1170_bases
ATGAAAATTAACTATCCGTTGCTGGCGCTGGCGATTGGCGCGTTTGGTATCGGGACAACGGAGTTCTCGCCAATGGGCTT
GTTGCCCGTCATTGCGCGCGGTGTGGATGTCTCGATTCCCGCTGCCGGAATGTTAATCAGTGCCTATGCAGTTGGCGTAA
TGGTTGGCGCGCCGCTGATGACGCTTCTACTTTCTCATCGTGCCCGCCGCAGTGCGTTGATTTTCCTGATGGCAATTTTC
ACGCTCGGCAACGTACTTTCCGCCATCGCGCCGGATTATATGACCCTGATGCTTTCACGCATTTTGACCAGCCTGAATCA
CGGAGCATTTTTTGGTTTGGGTTCAGTCGTGGCCGCAAGCGTGGTGCCAAAACATAAACAGGCCAGCGCAGTTGCCACTA
TGTTTATGGGGTTAACCCTGGCAAATATCGGTGGCGTGCCGGCGGCGACCTGGTTGGGTGAAACCATCGGCTGGCGGATG
TCATTTCTGGCAACGGCGGGGCTGGGAGTGATTTCAATGGTAAGTCTGTTCTTCTCATTACCTAAAGGTGGTGCAGGGGC
ACGACCTGAAGTGAAAAAAGAGCTGGCGGTATTAATGCGTCCGCAGGTGCTGTCTGCATTGCTGACGACGGTACTGGGAG
CTGGTGCAATGTTTACTCTCTACACCTATATCTCTCCGGTACTGCAAAGTATTACCCACGCAACACCGGTGTTCGTCACG
GCAATGCTGGTGCTGATTGGTGTCGGATTCTCTATCGGTAACTATCTCGGCGGCAAACTGGCAGATCGTTCAGTTAACGG
CACGTTGAAAGGCTTTTTGTTGCTGCTGATGGTGATTATGCTGGCAATCCCGTTCCTGGCCCGCAATAAGTTCGGCGCAG
CTATTAGCATGGCGGTGTGGGGCGCTGCAACCTTTGCGGTCGTACCGCCGTTACAGATGCGCGTGATGCGTGTCGCCAGT
GAAGCGCCAGGTCTGTCTTCATCAGTCAATATTGGTGCCTTTAATCTTGGAAATGCGCTGGGAGCAGCTGCTGGTGGTGC
GGTAATTTCCGCTGGGCTGGGATACAGCTTTGTGCCGGTGATGGGGGCGATTGTCGCGGGACTGGCATTATTGCTGGTGT
TTATGTCAGCCAGAAAACAACCTGAAACAGTTTGCGTTGCTAACAGCTAA

Upstream 100 bases:

>100_bases
TGTTTTCTCTTTTTGTTATTTTCATTTTTTTGTGATTGCTGTCATGCTTTCGCCACTTTAATGAATATCGCGTAATGACG
CGAAGAGGTGGAGATAAGGC

Downstream 100 bases:

>100_bases
TTAAACAAAAACGCAGAAGGATAACCTTCTGCGTTACAGTTGCTGACAACGTGCGATTTATCTTGCCGAATGCGCTGTTA
ACGCCTCATCCGCGTTGGCA

Product: transporter, major facilitator family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIF
TLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRM
SFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVT
AMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNKFGAAISMAVWGAATFAVVPPLQMRVMRVAS
EAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS

Sequences:

>Translated_389_residues
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIF
TLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRM
SFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVT
AMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNKFGAAISMAVWGAATFAVVPPLQMRVMRVAS
EAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>Mature_389_residues
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIF
TLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRM
SFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVT
AMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNKFGAAISMAVWGAATFAVVPPLQMRVMRVAS
EAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS

Specific function: Unknown

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily

Homologues:

Organism=Escherichia coli, GI1787947, Length=389, Percent_Identity=99.4858611825193, Blast_Score=749, Evalue=0.0,
Organism=Escherichia coli, GI1786595, Length=379, Percent_Identity=32.4538258575198, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1787808, Length=380, Percent_Identity=30, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI145693198, Length=327, Percent_Identity=26.9113149847095, Blast_Score=106, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YDHP_ECO57 (Q8X625)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B85773
- PIR:   F90924
- RefSeq:   NP_288093.1
- RefSeq:   NP_310393.1
- ProteinModelPortal:   Q8X625
- EnsemblBacteria:   EBESCT00000025444
- EnsemblBacteria:   EBESCT00000058572
- GeneID:   912314
- GeneID:   961620
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z2679
- KEGG:   ecs:ECs2366
- GeneTree:   EBGT00050000008819
- HOGENOM:   HBG732715
- OMA:   INVGAFN
- ProtClustDB:   CLSK880157
- BioCyc:   ECOL83334:ECS2366-MONOMER
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 40036; Mature: 40036

Theoretical pI: Translated: 10.91; Mature: 10.91

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2052d778)-; HASH(0x2131f5b4)-; HASH(0x21342ec4)-; HASH(0x2133169c)-; HASH(0x20ff0544)-; HASH(0x1feb8788)-; HASH(0x21032624)-; HASH(0x212a7c38)-; HASH(0x1fa5ad2c)-; HASH(0x20e7be50)-; HASH(0x2058fb1c)-; HASH(0x205a9bd4)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLM
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
TLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSL
HCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHH
AMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNKFGAAISMAVW
HHHHHHHCCHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPV
HHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHHHHHCCHHHHHCCCHHHHHH
MGAIVAGLALLLVFMSARKQPETVCVANS
HHHHHHHHHHHHHHHHCCCCCCEEEECCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHCCCCCCEEEECCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796