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The map label for this gene is nanE [H]

Identifier: 209396728

GI number: 209396728

Start: 4207361

End: 4208050

Strand: Reverse

Name: nanE [H]

Synonym: ECH74115_4540

Alternate gene names: 209396728

Gene position: 4208050-4207361 (Counterclockwise)

Preceding gene: 209397614

Following gene: 209396911

Centisome position: 75.52

GC content: 57.97

Gene sequence:

>690_bases
ATGTCGTTACTTGCACAACTGGATCAAAAAATCGCTGCTAACGGTGGCCTGATTGTCTCCTGCCAGCCGGTTCCGGACAG
CCCGCTCGATAAACCCGAAATCGTCGCAGCCATGGCATTAGCGGCAGAGCAGGCGGGCGCGGTTGCCATTCGCATCGAAG
GTGTGGCAAATCTGCAAGCCACGCGTGCGGTGGTGAGCGTGCCGATTATTGGAATTGTGAAACGCGATCTGGAGGATTCT
CCGGTACGCATCACGGCCTATATTGAAGATGTCGATGCGCTGGCGCAGGCGGGCGCGGACATTATCGCCATTGACGGCAC
CGACCGCCCGCGTCCGGTGCCTGTTGAAACGCTGCTGGCACGTATTCATCATCACGGTTTACTGGCGATGACCGACTGCT
CAACGCCGGAAGACGGCCTGGCATGCCAAAAGCTGGGAGCCGAAATTATTGGCACTACGCTTTCTGGCTATACCACGCCT
GAAACGCCAGAAGAGCCGGATCTGACGCTGGTGAAAAGGTTGAGCGACGCCGGATGTCGGGTGATTGCCGAAGGGCGTTA
CAACACGCCTGCTCAGGCGGCTGATGCGATGCGCCACGGCGCGTGGGCGGTGACGGTCGGTTCTGCCATTACGCGTCTTG
AACACATTTGTCAGTGGTACAACACAGCGATGAAAAAGGCGGTGCTATGA

Upstream 100 bases:

>100_bases
GTGCCGTGCCGTTTGGCAGCGCCAAAAACGATTTAGTCAAAACCAAAAGTTAATCCTGTTGCCCGGTCTCTGTATCGGGC
CTTTCGCTAAGGGAAGATGT

Downstream 100 bases:

>100_bases
CCACACTGGCGATTGATATCGGCGGTACTAAACTTGCCGCCGCGCTGATTGGCGCTGACGGGCAGATCCGCGATCGTCGT
GAACTTCCTACGCCAGCCAG

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQAGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDS
PVRITAYIEDVDALAQAGADIIAIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTP
ETPEEPDLTLVKRLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQWYNTAMKKAVL

Sequences:

>Translated_229_residues
MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQAGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDS
PVRITAYIEDVDALAQAGADIIAIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTP
ETPEEPDLTLVKRLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQWYNTAMKKAVL
>Mature_228_residues
SLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQAGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSP
VRITAYIEDVDALAQAGADIIAIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTPE
TPEEPDLTLVKRLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQWYNTAMKKAVL

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential) [H]

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family [H]

Homologues:

Organism=Escherichia coli, GI1789617, Length=229, Percent_Identity=99.1266375545851, Blast_Score=456, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060 [H]

Pfam domain/function: PF04131 NanE [H]

EC number: =5.1.3.9 [H]

Molecular weight: Translated: 24159; Mature: 24028

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQAGAVAIRIEGVANLQA
CCHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHH
TRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADIIAIDGTDRPRPVPVETLLA
HHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHH
RIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTPETPEEPDLTLVKRLSDAGCR
HHHHCCCEEEECCCCCCCCHHHHHHCHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCE
VIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQWYNTAMKKAVL
EEECCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQAGAVAIRIEGVANLQA
CHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHH
TRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADIIAIDGTDRPRPVPVETLLA
HHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHH
RIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTPETPEEPDLTLVKRLSDAGCR
HHHHCCCEEEECCCCCCCCHHHHHHCHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCE
VIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQWYNTAMKKAVL
EEECCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA