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The map label for this gene is gatY [H]

Identifier: 209396304

GI number: 209396304

Start: 4461619

End: 4462479

Strand: Direct

Name: gatY [H]

Synonym: ECH74115_4828

Alternate gene names: 209396304

Gene position: 4461619-4462479 (Clockwise)

Preceding gene: 209396982

Following gene: 209400722

Centisome position: 80.07

GC content: 49.48

Gene sequence:

>861_bases
ATGCCATTAGTTAATGGACGGATACTGCTCGACCGCATTCAGGAAAAACGGGTATTAGCGGGCGCATTTAATACCACCAA
TCTGGAGACGACAATTTCAATTTTAAACGCTATTGAGCGTTCGGGATTACCCAACTTCATTCAGATTGCGCCAACCAATG
CACAACTCTCGGGATACGATTACATTTATGAAATCGTGAAACGTCACGCCGATAAAATGGATGTTCCGGTCAGTCTTCAT
CTGGATCACGGGAAAACCCAGGAGGATGTTAAACAGGCGGTGCGCGCGGGCTTTACCTCGGTCATGATTGACGGTGCCGC
ATTCTCTTTTGAAGAGAATATCGCTTTCACCCAGGAAGCTGTCGATTTCTGTAAATCCTATGGCGTACCGGTTGAAGCGG
AGCTGGGGGCGATTCTCGGCAAAGAAGATGATCACGTCAGCGAAGCCGATTGCAAAACGGAACCGGAAAAGGTGAAGACC
TTTGTCGAGCGTACCGGTTGCGACATGCTGGCAGTTTCTATTGGCAACGTTCATGGCCTGGACGATATACCGCGTATCGA
TATCCCCCTGCTGAAGCGCATTGCCGAAGTCTGTCCGGTGCCGTTGGTTATTCACGGCGGCTCCGGTATCGCCCCGGAGA
TATTACGCAGCTTTGTTAATTATCGCGTCGCTAAAGTAAATATCGCCAGCGATCTGCGCAAAGCGTTTATCACCGCCGTC
GGCAAAGCGTATGTGAATAATCACAACGAGGCGAATCTGGCACGAGTCATGGCATCAGCAAAAAACGCCGTCGAGGAAGA
TGTGTATAGCAAAATCCTGATGATGAATGAGGGGCATCGGTTGGTTAGAAAGGCATCTTAA

Upstream 100 bases:

>100_bases
GATGATGAAAACGAGGCCATACAGACTCTCACCGACTTATTTCGCGACCGCTTCGGTGAAGCTGAATAATTAACTGATAT
TAAAAGATGAGGTTTTCAAT

Downstream 100 bases:

>100_bases
GAGCCACAAAAATATAGCGGCGCAACAGAAATTGTTGGGCCGCTATAAGTTATAAATGATTCAAACGCTCATTCAGTGTT
TCAATAATATAGGTATTAAC

Product: putative fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: TBPA; TagBP aldolase; D-tagatose-bisphosphate aldolase class II; Ketose 1,6-bisphosphate aldolase class II; Tagatose-bisphosphate aldolase [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MPLVNGRILLDRIQEKRVLAGAFNTTNLETTISILNAIERSGLPNFIQIAPTNAQLSGYDYIYEIVKRHADKMDVPVSLH
LDHGKTQEDVKQAVRAGFTSVMIDGAAFSFEENIAFTQEAVDFCKSYGVPVEAELGAILGKEDDHVSEADCKTEPEKVKT
FVERTGCDMLAVSIGNVHGLDDIPRIDIPLLKRIAEVCPVPLVIHGGSGIAPEILRSFVNYRVAKVNIASDLRKAFITAV
GKAYVNNHNEANLARVMASAKNAVEEDVYSKILMMNEGHRLVRKAS

Sequences:

>Translated_286_residues
MPLVNGRILLDRIQEKRVLAGAFNTTNLETTISILNAIERSGLPNFIQIAPTNAQLSGYDYIYEIVKRHADKMDVPVSLH
LDHGKTQEDVKQAVRAGFTSVMIDGAAFSFEENIAFTQEAVDFCKSYGVPVEAELGAILGKEDDHVSEADCKTEPEKVKT
FVERTGCDMLAVSIGNVHGLDDIPRIDIPLLKRIAEVCPVPLVIHGGSGIAPEILRSFVNYRVAKVNIASDLRKAFITAV
GKAYVNNHNEANLARVMASAKNAVEEDVYSKILMMNEGHRLVRKAS
>Mature_285_residues
PLVNGRILLDRIQEKRVLAGAFNTTNLETTISILNAIERSGLPNFIQIAPTNAQLSGYDYIYEIVKRHADKMDVPVSLHL
DHGKTQEDVKQAVRAGFTSVMIDGAAFSFEENIAFTQEAVDFCKSYGVPVEAELGAILGKEDDHVSEADCKTEPEKVKTF
VERTGCDMLAVSIGNVHGLDDIPRIDIPLLKRIAEVCPVPLVIHGGSGIAPEILRSFVNYRVAKVNIASDLRKAFITAVG
KAYVNNHNEANLARVMASAKNAVEEDVYSKILMMNEGHRLVRKAS

Specific function: Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6- bisphosphate (T

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase KbaY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=284, Percent_Identity=35.9154929577465, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI87082041, Length=277, Percent_Identity=36.4620938628159, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1788072, Length=221, Percent_Identity=38.0090497737557, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789293, Length=244, Percent_Identity=27.4590163934426, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000771
- InterPro:   IPR011288 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.40 [H]

Molecular weight: Translated: 31388; Mature: 31257

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00602 ALDOLASE_CLASS_II_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVNGRILLDRIQEKRVLAGAFNTTNLETTISILNAIERSGLPNFIQIAPTNAQLSGYD
CCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHH
YIYEIVKRHADKMDVPVSLHLDHGKTQEDVKQAVRAGFTSVMIDGAAFSFEENIAFTQEA
HHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHEEECCCCCCHHCCHHHHHHH
VDFCKSYGVPVEAELGAILGKEDDHVSEADCKTEPEKVKTFVERTGCDMLAVSIGNVHGL
HHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
DDIPRIDIPLLKRIAEVCPVPLVIHGGSGIAPEILRSFVNYRVAKVNIASDLRKAFITAV
CCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHEEEEEEHHHHHHHHHHHHH
GKAYVNNHNEANLARVMASAKNAVEEDVYSKILMMNEGHRLVRKAS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC
>Mature Secondary Structure 
PLVNGRILLDRIQEKRVLAGAFNTTNLETTISILNAIERSGLPNFIQIAPTNAQLSGYD
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHH
YIYEIVKRHADKMDVPVSLHLDHGKTQEDVKQAVRAGFTSVMIDGAAFSFEENIAFTQEA
HHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCCCHHEEECCCCCCHHCCHHHHHHH
VDFCKSYGVPVEAELGAILGKEDDHVSEADCKTEPEKVKTFVERTGCDMLAVSIGNVHGL
HHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCC
DDIPRIDIPLLKRIAEVCPVPLVIHGGSGIAPEILRSFVNYRVAKVNIASDLRKAFITAV
CCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHEEEEEEHHHHHHHHHHHHH
GKAYVNNHNEANLARVMASAKNAVEEDVYSKILMMNEGHRLVRKAS
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA