Click here to switch to the map view.

The map label for this gene is yhaK

Identifier: 209396124

GI number: 209396124

Start: 4097031

End: 4097732

Strand: Direct

Name: yhaK

Synonym: ECH74115_4421

Alternate gene names: 209396124

Gene position: 4097031-4097732 (Clockwise)

Preceding gene: 209397210

Following gene: 209400283

Centisome position: 73.53

GC content: 53.28

Gene sequence:

>702_bases
ATGATTACTACCCGAACTGCCAGGCAGTGTGGACAAGCAGACTACGGATGGTTGCAGGCCCGGTATACTTTTTCCTTTGG
ACACTACTTCGACCCGAAATTGTTAGGCTATGCCTCCCTGCGTGTGCTTAACCAGGAAGTGCTGGCCCCAGGTGCCGCCT
TTCAGCCGCGAACCTATCCCAAAGTCGATATTTTAAATGTGATTCTGGATGGAGAAGCAGAGTATCGCGACAGCGAAGGC
AATCATGTTCAGGCCAGCGCCGGTGAGGCGTTGCTGCTCTCTACCCAGCCGGGTGTCAGCTACAGCGAACACAATCTCAG
CAAAGACAAACCGTTAACACGAATGCAGCTTTGGCTGGACGCCTGCCCGCAGCGAGAGAATCCGCTGATTCAAAAACTGG
CGCTTAATATGGGCAAGCAGCATTTAATCGCCTCGCCAGAGGGTGCGATGGGAAGCCTGCAATTACGCCAGCAAGTGTGG
CTGCACCATATCGTGCTCGACAAAGGCGAAAGTGCGAATTTCCAGTTGCATGGGCCACGCACGTATTTGCAATCGATTCA
CGGGAAATTTCATGCGCTTACGCATCATGAAGAGAAAGCGGCGCTGACCTGCGGTGATGGGGCGTTTATTCGTGACGAGG
CTAACATTACGCTGGTTGCCGATTCCCCACTGCGCGCTTTGCTGATAGATTTGCCTGTCTAG

Upstream 100 bases:

>100_bases
TTCTCATTCAGGAAATTTGAACATACCGGGCAGAATATCTGGCTAACAATGTAGCGTCCAGCCCCTTACCATAAAAGGAA
GTAAAGAGAGGTCAAGAATT

Downstream 100 bases:

>100_bases
TTGTTTTTACAGGGAGATGATGATGAGTAAAAAATCGGCCAAAAAGCGCCAGCCAGTGAAGCCCGTGGTGGCGAAAGAAC
CTGCTCGCACCGCCAAAAAT

Product: pirin family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEG
NHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQHLIASPEGAMGSLQLRQQVW
LHHIVLDKGESANFQLHGPRTYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV

Sequences:

>Translated_233_residues
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEG
NHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQHLIASPEGAMGSLQLRQQVW
LHHIVLDKGESANFQLHGPRTYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV
>Mature_233_residues
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEG
NHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQHLIASPEGAMGSLQLRQQVW
LHHIVLDKGESANFQLHGPRTYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV

Specific function: Does not have quercetin 2,3-dioxygenase activity

COG id: COG1741

COG function: function code R; Pirin-related protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pirin family

Homologues:

Organism=Escherichia coli, GI1789493, Length=233, Percent_Identity=99.1416309012876, Blast_Score=480, Evalue=1e-137,
Organism=Escherichia coli, GI1789847, Length=235, Percent_Identity=34.8936170212766, Blast_Score=133, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHAK_ECO57 (P58115)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   C85972
- PIR:   D91127
- RefSeq:   NP_289680.1
- RefSeq:   NP_312015.1
- ProteinModelPortal:   P58115
- SMR:   P58115
- EnsemblBacteria:   EBESCT00000024647
- EnsemblBacteria:   EBESCT00000055386
- GeneID:   916176
- GeneID:   958582
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4460
- KEGG:   ecs:ECs3988
- GeneTree:   EBGT00050000010710
- HOGENOM:   HBG370454
- OMA:   LRQQVWI
- ProtClustDB:   CLSK880589
- BioCyc:   ECOL83334:ECS3988-MONOMER
- GO:   GO:0005737
- InterPro:   IPR011051
- InterPro:   IPR012093
- InterPro:   IPR003829
- InterPro:   IPR014710
- Gene3D:   G3DSA:2.60.120.10
- PANTHER:   PTHR13903
- PIRSF:   PIRSF006232

Pfam domain/function: PF02678 Pirin; SSF51182 RmlC_like_cupin

EC number: NA

Molecular weight: Translated: 25935; Mature: 25935

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYP
CCCCCCHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLD
CCEEEEEEECCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
ACPQRENPLIQKLALNMGKQHLIASPEGAMGSLQLRQQVWLHHIVLDKGESANFQLHGPR
HCCCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHEEECCCCCCEEEECHH
TYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV
HHHHHHCCHHEEEECCCCCCEEEECCCCEEECCCCEEEEECCCCEEEEEECCC
>Mature Secondary Structure
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYP
CCCCCCHHHCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
KVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLD
CCEEEEEEECCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
ACPQRENPLIQKLALNMGKQHLIASPEGAMGSLQLRQQVWLHHIVLDKGESANFQLHGPR
HCCCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHEEECCCCCCEEEECHH
TYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV
HHHHHHCCHHEEEECCCCCCEEEECCCCEEECCCCEEEEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796