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The map label for this gene is arcC

Identifier: 209395866

GI number: 209395866

Start: 646214

End: 647107

Strand: Direct

Name: arcC

Synonym: ECH74115_0622

Alternate gene names: 209395866

Gene position: 646214-647107 (Clockwise)

Preceding gene: 209398161

Following gene: 209397071

Centisome position: 11.6

GC content: 56.94

Gene sequence:

>894_bases
ATGAAAACACTGGTTGTAGCTCTTGGGGGCAACGCCTTACTCCAGCGCGGTGAGGCGCTGACGGCAGAAAATCAATATCG
CAATATCGCCAGTGCTGTACCCGCGCTGGCGCGCCTGGCCCGTTCTTATCGGCTGGCGATTGTTCACGGCAACGGGCCGC
AGGTGGGGCTGCTGGCATTGCAGAATCTGGCGTGGAAAGAGGTAGAACCGTATCCGCTGGATGTGCTGGTGGCAGAAAGT
CAGGGGATGATTGGCTATATGCTGGCGCAGAGTTTGAGCGCACAGCCGCAGATGCCGCCTGTCACGACGGTGCGGACGCG
CATTGAAGTTTCGCCTGATGATCCGGCGTTTTTGCAGCCAGAGAAATTTATTGGTCCGGTTTATCAGCCAGAAGAACAAG
AGGCACTGGAAGCGGCTTACGGCTGGCAGATGAAACGTGATGGTAAATATTTGCGCCGGGTGGTGGCGTCTCCGCAACCG
CGTAAAATTCTCGACAGCGAAGCCATCGAGTTGTTGCTCAAAGAGGGGCATGTGGTGATTTGCAGTGGCGGCGGCGGTGT
GCCTGTGACGGATGACGGAGCAGGGAGTGAAGCAGTGATTGATAAAGATCTCGCCGCTGCGTTGCTCGCCGAGCAAATTA
ACGCCGATGGACTGGTGATCCTCACCGATGCTGATGCGGTATATGAAAACTGGGGAATGCCGCAGCAACGTGCCATTCGC
CATGCCACACCGGATGAGTTAGCGCCATTTGCCAAAGCCGATGGTTCGATGGGGCCGAAGGTAACGGCGGTGAGTGGTTA
TGTCAGAAGCCGTGGTAAACCCGCGTGGATTGGGGCGTTATCGCGAATTGAAGAGACGCTGGCGGGCGAAGCGGGGACCT
GTATTTCGCTGTAG

Upstream 100 bases:

>100_bases
CCGCTGTTGCGATTGATTCGCTGCTGGCGCTGGGGCATACGTCAGGGGCAGATACACTGCTGGGGTTCTGGCTTGGCCAA
CAATTATTACAAGGAAAACC

Downstream 100 bases:

>100_bases
TGATGAGAGCATCCGGCAATCGGCGCACCATGCCTGATGCGACGCTTGACGCGTCTTATCAGGCCTACAATGGGTACCGG
ATCGGTGTAGGCCGGATAAG

Product: carbamate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYRLAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAES
QGMIGYMLAQSLSAQPQMPPVTTVRTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQP
RKILDSEAIELLLKEGHVVICSGGGGVPVTDDGAGSEAVIDKDLAAALLAEQINADGLVILTDADAVYENWGMPQQRAIR
HATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAWIGALSRIEETLAGEAGTCISL

Sequences:

>Translated_297_residues
MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYRLAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAES
QGMIGYMLAQSLSAQPQMPPVTTVRTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQP
RKILDSEAIELLLKEGHVVICSGGGGVPVTDDGAGSEAVIDKDLAAALLAEQINADGLVILTDADAVYENWGMPQQRAIR
HATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAWIGALSRIEETLAGEAGTCISL
>Mature_297_residues
MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYRLAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAES
QGMIGYMLAQSLSAQPQMPPVTTVRTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQP
RKILDSEAIELLLKEGHVVICSGGGGVPVTDDGAGSEAVIDKDLAAALLAEQINADGLVILTDADAVYENWGMPQQRAIR
HATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAWIGALSRIEETLAGEAGTCISL

Specific function: Arginine degradation via arginine deiminase; third step. [C]

COG id: COG0549

COG function: function code E; Carbamate kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbamate kinase family

Homologues:

Organism=Escherichia coli, GI1786732, Length=297, Percent_Identity=98.989898989899, Blast_Score=592, Evalue=1e-170,
Organism=Escherichia coli, GI1789238, Length=312, Percent_Identity=39.7435897435897, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1786516, Length=313, Percent_Identity=38.6581469648562, Blast_Score=147, Evalue=8e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARCC_ECO57 (Q8XCV5)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B85552
- PIR:   G90701
- RefSeq:   NP_286270.1
- RefSeq:   NP_308610.1
- ProteinModelPortal:   Q8XCV5
- SMR:   Q8XCV5
- EnsemblBacteria:   EBESCT00000024625
- EnsemblBacteria:   EBESCT00000058440
- GeneID:   916781
- GeneID:   957524
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z0676
- KEGG:   ecs:ECs0583
- GeneTree:   EBGT00050000010999
- HOGENOM:   HBG296625
- OMA:   IVICCGG
- ProtClustDB:   PRK09411
- BioCyc:   ECOL83334:ECS0583-MONOMER
- GO:   GO:0005737
- InterPro:   IPR001048
- InterPro:   IPR003964
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000723
- PRINTS:   PR01469
- TIGRFAMs:   TIGR00746

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.2

Molecular weight: Translated: 31732; Mature: 31732

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYRLAIVHGNGPQVGLLAL
CCEEEEEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHH
QNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVTTVRTRIEVSPDDPAFLQP
HHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCC
EKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQPRKILDSEAIELLLKEGHVVI
HHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEE
CSGGGGVPVTDDGAGSEAVIDKDLAAALLAEQINADGLVILTDADAVYENWGMPQQRAIR
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCHHHHHH
HATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAWIGALSRIEETLAGEAGTCISL
CCCHHHHCCHHHCCCCCCCEEEEEHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEECC
>Mature Secondary Structure
MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYRLAIVHGNGPQVGLLAL
CCEEEEEECCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHH
QNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVTTVRTRIEVSPDDPAFLQP
HHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCC
EKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQPRKILDSEAIELLLKEGHVVI
HHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCEEE
CSGGGGVPVTDDGAGSEAVIDKDLAAALLAEQINADGLVILTDADAVYENWGMPQQRAIR
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCHHHHHH
HATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAWIGALSRIEETLAGEAGTCISL
CCCHHHHCCHHHCCCCCCCEEEEEHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796