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The map label for this gene is ompR [H]

Identifier: 209395753

GI number: 209395753

Start: 5234774

End: 5235481

Strand: Direct

Name: ompR [H]

Synonym: ECH74115_5596

Alternate gene names: 209395753

Gene position: 5234774-5235481 (Clockwise)

Preceding gene: 209399923

Following gene: 209396346

Centisome position: 93.95

GC content: 55.23

Gene sequence:

>708_bases
ATGAAACCCGTCGTGCTGGTGGTGGATGATGACACGGCTATCTGCGCACTGTTGCAGGACGTGTTAAGTGAACATGTCTT
TACGGTTTCAGTCTGCCATACCGGACAGGAGGCCATATTGCGTATTGAGGGCGATCCTGACATTGCGCTGGTGGTGCTGG
ATATGATGCTACCCGATACCAACGGCCTGAGGGTATTGCAGCAAATCCAGAAACTGCGTCCGACATTGCCGGTGGTGATG
TTGACCGGCATGGGCAGTGAGTCTGATGTGGTGGTCGGGCTGGAAATGGGCGCGGATGATTACATCTGCAAACCGTTCAC
CCCGCGGGTGGTGGTCGCACGACTGAAAGCGGTGTTGCGACGGGTTGGCGCGCTGGCGGTTAATGACGAGAAAAGCGCCG
GGCTGTCATTCAATGGCTGGTATCTCGATACCATGCGCTGCCAGTTGCACAATCCGCTTCAGCAACATGTCGAGTTAACT
CAGGGCGAATATGGCTTGTTACTGGCTCTGGCGCAAAACGCGCGTCGGGTATTGAGCCGCGAGCAGTTGCTGGCGTTCAC
CCACAGCGACAGCGTGGAGGTGTTTGATCGCACCATCGACGTATTAATCATGCGCTTACGACGCAAAATCGAACTCAACC
CGCATCAGCCGATGTTGATTAAAACTCTGCGCGGTCTGGGGTATGTCTTCGCTGCCGACGTGCATTAA

Upstream 100 bases:

>100_bases
TGACCTGACTTATATTTTTATTATTTATATTACTTTCAGCTTTCACTTCGACAAGAAGTACGCACAATGATTAATCAGAT
GAATGATGCGGAGTGTAACC

Downstream 100 bases:

>100_bases
TCCGACATTTCTGTTTGCAGCTCTTCCAGCGTTTTCGCCCCGTCGATGGCATTGGCGCATAACAGGCTTGCCCGCGCGCA
GGCGTGTGCCAGTTTGATGC

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKPVVLVVDDDTAICALLQDVLSEHVFTVSVCHTGQEAILRIEGDPDIALVVLDMMLPDTNGLRVLQQIQKLRPTLPVVM
LTGMGSESDVVVGLEMGADDYICKPFTPRVVVARLKAVLRRVGALAVNDEKSAGLSFNGWYLDTMRCQLHNPLQQHVELT
QGEYGLLLALAQNARRVLSREQLLAFTHSDSVEVFDRTIDVLIMRLRRKIELNPHQPMLIKTLRGLGYVFAADVH

Sequences:

>Translated_235_residues
MKPVVLVVDDDTAICALLQDVLSEHVFTVSVCHTGQEAILRIEGDPDIALVVLDMMLPDTNGLRVLQQIQKLRPTLPVVM
LTGMGSESDVVVGLEMGADDYICKPFTPRVVVARLKAVLRRVGALAVNDEKSAGLSFNGWYLDTMRCQLHNPLQQHVELT
QGEYGLLLALAQNARRVLSREQLLAFTHSDSVEVFDRTIDVLIMRLRRKIELNPHQPMLIKTLRGLGYVFAADVH
>Mature_235_residues
MKPVVLVVDDDTAICALLQDVLSEHVFTVSVCHTGQEAILRIEGDPDIALVVLDMMLPDTNGLRVLQQIQKLRPTLPVVM
LTGMGSESDVVVGLEMGADDYICKPFTPRVVVARLKAVLRRVGALAVNDEKSAGLSFNGWYLDTMRCQLHNPLQQHVELT
QGEYGLLLALAQNARRVLSREQLLAFTHSDSVEVFDRTIDVLIMRLRRKIELNPHQPMLIKTLRGLGYVFAADVH

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=38.7931034482759, Blast_Score=153, Evalue=9e-39,
Organism=Escherichia coli, GI1788394, Length=235, Percent_Identity=36.1702127659575, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1790863, Length=236, Percent_Identity=33.0508474576271, Blast_Score=134, Evalue=4e-33,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=37.3913043478261, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=39.8268398268398, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=36.0515021459227, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=35.2173913043478, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=31.5789473684211, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=30.8370044052863, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=34.3612334801762, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=31.6455696202532, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=31.7180616740088, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=31.140350877193, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=32.3144104803493, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790437, Length=102, Percent_Identity=32.3529411764706, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26160; Mature: 26160

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVVLVVDDDTAICALLQDVLSEHVFTVSVCHTGQEAILRIEGDPDIALVVLDMMLPDT
CCCEEEEECCCHHHHHHHHHHHHHHEEEEEEEECCCEEEEEECCCCCEEEEEEEHHCCCC
NGLRVLQQIQKLRPTLPVVMLTGMGSESDVVVGLEMGADDYICKPFTPRVVVARLKAVLR
CHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCEECCCCHHHHHHHHHHHHH
RVGALAVNDEKSAGLSFNGWYLDTMRCQLHNPLQQHVELTQGEYGLLLALAQNARRVLSR
HHCCEEECCCCCCCCEECCEEEEEHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EQLLAFTHSDSVEVFDRTIDVLIMRLRRKIELNPHQPMLIKTLRGLGYVFAADVH
HHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEECCC
>Mature Secondary Structure
MKPVVLVVDDDTAICALLQDVLSEHVFTVSVCHTGQEAILRIEGDPDIALVVLDMMLPDT
CCCEEEEECCCHHHHHHHHHHHHHHEEEEEEEECCCEEEEEECCCCCEEEEEEEHHCCCC
NGLRVLQQIQKLRPTLPVVMLTGMGSESDVVVGLEMGADDYICKPFTPRVVVARLKAVLR
CHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCCEECCCCHHHHHHHHHHHHH
RVGALAVNDEKSAGLSFNGWYLDTMRCQLHNPLQQHVELTQGEYGLLLALAQNARRVLSR
HHCCEEECCCCCCCCEECCEEEEEHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EQLLAFTHSDSVEVFDRTIDVLIMRLRRKIELNPHQPMLIKTLRGLGYVFAADVH
HHHEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]