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The map label for this gene is AslB4 [C]

Identifier: 20809080

GI number: 20809080

Start: 2641883

End: 2643208

Strand: Reverse

Name: AslB4 [C]

Synonym: TTE2746

Alternate gene names: 20809080

Gene position: 2643208-2641883 (Counterclockwise)

Preceding gene: 20809081

Following gene: 20809079

Centisome position: 98.28

GC content: 31.83

Gene sequence:

>1326_bases
ATGAAACCGTCTAGATATAACTTTTTCTTTGACTTTCCTGAAGAGCCGGAGAAAATAGTAGCTTATAACTCAAGAACAGG
AGCTTTAGCCTTAATGGAAAAAAAGAATCACGACAAGTATAAAAATTATGTAGAAAAAGGCATTTCGATTGATGACAGTA
AATTAATAGAAGACTTGAAAAAAGGTCAATTTCTCATAGATGACAATATTGACGAACTTCAGCTATTACGTTTCAATCTC
TGGCGGAGTAGATTTAATGACAAAAATTTGGGTTTAACTATTGCACCTACATTAGGATGTAATTTTGCTTGTGTATACTG
CTACGAAAAGGGCAATCAGAAAGATGTATTTATGAGTGAAGAAGTACAGGATAAAATAGTTAAATATATAAAGCAGCGGA
TAAAGTATTTGCAGAGTGTAAATATTACTTGGTATGGAGGGGAACCTTTATTAGCTTTTGACATTGTCAAAGATATGTCA
GAAAAAATTATAAAGCTCTGTGATGAAAATGAAGTTATGTATGGAGCATCTATTATAACGAATGGATATAACTTGACAAG
GGAAGTAGTGGAACAATTTAGGAACCTGCGATTATCATTTATACAAATAACATTGGATGGTCCCCAGGATGTACACGATA
AAAGACGTCCTTTAAAAAGTGGACAGGGAACTTTTGAAAAGATACTAGTTAACATAGAAGAAAATATTGATATAATGCCA
AATATTTCTTTAAGGATAAACGTAGACAAAGAAAACGTAAACAGAGTTAATGAAATATTAGATGGGTTGGAAAGAAGAGG
ATTGAAAAATAAACTTAGTGTTTATTTGGGATATGTAGAACCTACAAATGATTGTTATGTACCAAATAAGTGTCTATCTA
TGCATGAATATTCTAAGGTTACTTATATGTTTGAAAAAGTGTTAAAAGAAAGAGGTTTTTCGAATAATTTAATGCATAAG
TACCCCCATTTAAAATACAATTTTTGTGGAGCAGATAGTGTAAATTCAATGGTGATAGACCCGGAGGGATACATATACAA
GTGCTGGTCTGATATAGGGATAGAAGAGTATAGGGTAGGAAATATATTAAACGACACATCCTTAGTTTCTTTAAATGTTG
ATAAATATATGGAATATCTTCTTTATGACCCTACGATAGACGAGATGTGTATTGATTGCAAGCTCCTGCCAATTTGTATA
GGAGGATGTCCAAGGAGAAGAATAGAAAGAATGACAGAAAGATGTGGAGATTATAAGTATGTTTTAGAAGAATATTTGAA
GGATATAGCAAAAGAGCTATTAGAGAAAAAACAAGAAAAGGTTTAA

Upstream 100 bases:

>100_bases
AAATAGATTTCAGGCAGCCTAGAAGCACATCTTAGAACTTTTATGTAGAAAAGTTTTTGAGATGAGCTCAGGATAAAAAT
TCTTTAAGGGGAGAAAGAAA

Downstream 100 bases:

>100_bases
ACCAATTTGAGTGTATATTTCAGATATTAATTTTGATTAGAATGTGCGCACATTCTATAATATACTGGATTGGAAAAAGG
AGGTGGAGAGAATGGAATAT

Product: arylsulfatase regulator (Fe-S oxidoreductase)

Products: NA

Alternate protein names: AnSME; Cys-type sulfatase-activating enzyme [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKPSRYNFFFDFPEEPEKIVAYNSRTGALALMEKKNHDKYKNYVEKGISIDDSKLIEDLKKGQFLIDDNIDELQLLRFNL
WRSRFNDKNLGLTIAPTLGCNFACVYCYEKGNQKDVFMSEEVQDKIVKYIKQRIKYLQSVNITWYGGEPLLAFDIVKDMS
EKIIKLCDENEVMYGASIITNGYNLTREVVEQFRNLRLSFIQITLDGPQDVHDKRRPLKSGQGTFEKILVNIEENIDIMP
NISLRINVDKENVNRVNEILDGLERRGLKNKLSVYLGYVEPTNDCYVPNKCLSMHEYSKVTYMFEKVLKERGFSNNLMHK
YPHLKYNFCGADSVNSMVIDPEGYIYKCWSDIGIEEYRVGNILNDTSLVSLNVDKYMEYLLYDPTIDEMCIDCKLLPICI
GGCPRRRIERMTERCGDYKYVLEEYLKDIAKELLEKKQEKV

Sequences:

>Translated_441_residues
MKPSRYNFFFDFPEEPEKIVAYNSRTGALALMEKKNHDKYKNYVEKGISIDDSKLIEDLKKGQFLIDDNIDELQLLRFNL
WRSRFNDKNLGLTIAPTLGCNFACVYCYEKGNQKDVFMSEEVQDKIVKYIKQRIKYLQSVNITWYGGEPLLAFDIVKDMS
EKIIKLCDENEVMYGASIITNGYNLTREVVEQFRNLRLSFIQITLDGPQDVHDKRRPLKSGQGTFEKILVNIEENIDIMP
NISLRINVDKENVNRVNEILDGLERRGLKNKLSVYLGYVEPTNDCYVPNKCLSMHEYSKVTYMFEKVLKERGFSNNLMHK
YPHLKYNFCGADSVNSMVIDPEGYIYKCWSDIGIEEYRVGNILNDTSLVSLNVDKYMEYLLYDPTIDEMCIDCKLLPICI
GGCPRRRIERMTERCGDYKYVLEEYLKDIAKELLEKKQEKV
>Mature_441_residues
MKPSRYNFFFDFPEEPEKIVAYNSRTGALALMEKKNHDKYKNYVEKGISIDDSKLIEDLKKGQFLIDDNIDELQLLRFNL
WRSRFNDKNLGLTIAPTLGCNFACVYCYEKGNQKDVFMSEEVQDKIVKYIKQRIKYLQSVNITWYGGEPLLAFDIVKDMS
EKIIKLCDENEVMYGASIITNGYNLTREVVEQFRNLRLSFIQITLDGPQDVHDKRRPLKSGQGTFEKILVNIEENIDIMP
NISLRINVDKENVNRVNEILDGLERRGLKNKLSVYLGYVEPTNDCYVPNKCLSMHEYSKVTYMFEKVLKERGFSNNLMHK
YPHLKYNFCGADSVNSMVIDPEGYIYKCWSDIGIEEYRVGNILNDTSLVSLNVDKYMEYLLYDPTIDEMCIDCKLLPICI
GGCPRRRIERMTERCGDYKYVLEEYLKDIAKELLEKKQEKV

Specific function: Involved in 'Cys-type' sulfatase maturation under anaerobic conditions. Catalyzes the post-translational modification of cysteine into 3-oxoalanine (also known as C(alpha)-formylglycine (FGly)), by a free radical chemical mechanism initiated via the reduc

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI87081923, Length=357, Percent_Identity=24.6498599439776, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 51620; Mature: 51620

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPSRYNFFFDFPEEPEKIVAYNSRTGALALMEKKNHDKYKNYVEKGISIDDSKLIEDLK
CCCCCCEEEECCCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHH
KGQFLIDDNIDELQLLRFNLWRSRFNDKNLGLTIAPTLGCNFACVYCYEKGNQKDVFMSE
CCCEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEEECCCCCCCEECH
EVQDKIVKYIKQRIKYLQSVNITWYGGEPLLAFDIVKDMSEKIIKLCDENEVMYGASIIT
HHHHHHHHHHHHHHHHHHHCCEEEECCCCEEHHHHHHHHHHHHHHHHCCCCEEECHHHEE
NGYNLTREVVEQFRNLRLSFIQITLDGPQDVHDKRRPLKSGQGTFEKILVNIEENIDIMP
CCHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHCCCCCCCCCHHHHHEECCCCCEECC
NISLRINVDKENVNRVNEILDGLERRGLKNKLSVYLGYVEPTNDCYVPNKCLSMHEYSKV
CCEEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHH
TYMFEKVLKERGFSNNLMHKYPHLKYNFCGADSVNSMVIDPEGYIYKCWSDIGIEEYRVG
HHHHHHHHHHCCCCCCCHHHCCCCEEEECCCCCCCCEEECCCCCEEEEEHHCCCCCEECC
NILNDTSLVSLNVDKYMEYLLYDPTIDEMCIDCKLLPICIGGCPRRRIERMTERCGDYKY
CEECCCEEEEEEHHHHHHHHHCCCCHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCHHH
VLEEYLKDIAKELLEKKQEKV
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPSRYNFFFDFPEEPEKIVAYNSRTGALALMEKKNHDKYKNYVEKGISIDDSKLIEDLK
CCCCCCEEEECCCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHH
KGQFLIDDNIDELQLLRFNLWRSRFNDKNLGLTIAPTLGCNFACVYCYEKGNQKDVFMSE
CCCEEECCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEEEECCCCCCCEECH
EVQDKIVKYIKQRIKYLQSVNITWYGGEPLLAFDIVKDMSEKIIKLCDENEVMYGASIIT
HHHHHHHHHHHHHHHHHHHCCEEEECCCCEEHHHHHHHHHHHHHHHHCCCCEEECHHHEE
NGYNLTREVVEQFRNLRLSFIQITLDGPQDVHDKRRPLKSGQGTFEKILVNIEENIDIMP
CCHHHHHHHHHHHHCCEEEEEEEEECCCCCHHHHHCCCCCCCCCHHHHHEECCCCCEECC
NISLRINVDKENVNRVNEILDGLERRGLKNKLSVYLGYVEPTNDCYVPNKCLSMHEYSKV
CCEEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHH
TYMFEKVLKERGFSNNLMHKYPHLKYNFCGADSVNSMVIDPEGYIYKCWSDIGIEEYRVG
HHHHHHHHHHCCCCCCCHHHCCCCEEEECCCCCCCCEEECCCCCEEEEEHHCCCCCEECC
NILNDTSLVSLNVDKYMEYLLYDPTIDEMCIDCKLLPICIGGCPRRRIERMTERCGDYKY
CEECCCEEEEEEHHHHHHHHHCCCCHHHHHHCCEEEEEECCCCCHHHHHHHHHHHCCHHH
VLEEYLKDIAKELLEKKQEKV
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA