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The map label for this gene is TldD [H]

Identifier: 20809065

GI number: 20809065

Start: 2622319

End: 2623614

Strand: Reverse

Name: TldD [H]

Synonym: TTE2724

Alternate gene names: 20809065

Gene position: 2623614-2622319 (Counterclockwise)

Preceding gene: 20809066

Following gene: 20809064

Centisome position: 97.55

GC content: 33.41

Gene sequence:

>1296_bases
ATGATGAGCCAAAAGGAGATAGTCAACTATACTCTTGAAGCCTTAAATAGAGCAGGTGCTCAGAAATCCCAAGTTAATCT
CACTTTTACAGAAAAGCATGAAGTCAACCTTGAAGCTAATGAATTTACTATGGTAAGAACAACCTTTGATACGGATATAG
TTTTAACAGCTATAAAAGATAAGAAAAAAGGTACTATTTCAATAAATAAATCCGATATTCAATCAATTGATTCTGCAGCA
CAAGATGTTATATTAGTTGCAGAGGCGTCACCTGAAGATGAGGCAAATGACATAGCCGAATATCAACCACCCAAAGTATT
TTCATCAGGGGATAGAACTCCAGATTTAGAAATGATGTATTACAGGATGAATGAATTAGTCAAACAAATAAAAGAAAAAT
ATCCCAAAATTATACTGATTCAAGCTTTTTTATATCATGAGTATAAACAAAGTTATTTTGTAAATTCCAATGGTGTTGAT
TATGTTTCTAATCAAGGTGTATATAACTTTTTTGCAATGTTTTCATCAAAGGACCAGGATAAAACCTCCTCTTTTAACTA
TACAAGTTTTTCTTTAAAAAACCTTGATAAAGAGCTATTAAATTGTGGCACTCTAGACATTTTACTAAAACAATTAGAAG
AGCAGACAAACACAAGACCTGTAGAAGGTAAATTTGTAGGTGATGTCATAATTTCTCCTGATGCTGTAAATGATATATTA
GATTTCCTCACAAGGTCGCTATCAGACAATTCTATAATATCTGGAACCAGTATATATAAAGATAAGCTTGAAAAGCAGAT
TGCAAGCCCTCTTTTGACTGTTCATTCTTGTCCTGTATCGGAGGAAATTTGTAGTGGCTATTTTGTCACGAAGGATGGGT
ACGAAGCTCGAAATATAACCATTATTGACAAAGGCGTATTAAAAAACTTTTTATTAAGTCTTTATGGTTCAAAAAAGACA
GGATTAAAATATGCCTATAATGATGGAGGTGCTTTTGTAATTGAACCAGGTGAAACAGCACTTGATGATATGATTAGATC
TGTAAAAAAAGGTATATTGCTTATGAGATTTTCAGGAGGGTATCCAAGTGACAGCGGTGATTTTTCCGGGGTTGCAAAAA
ATAGTTATCTGATTGAAGATGGCAAAATAAAATATCCTATAAGTGAAACGATGATTTCTGGCAACATTGCAGAGATGTTG
AAGAATATAACTGCAATCTCCAAAGAACAAGTCAATTTTGGGTGGCAGGTACTCCCATGGATTAGCGTGAAAGGGGTAAC
CATATCAGGAAAATAA

Upstream 100 bases:

>100_bases
AAATGGATAAGCAGTGGCTGGTGTGGTAAAAAACAGCCTATGCCCGTTGGAATGGCCGGTCCTGCAATCAAATGCCAGAT
CAACATAGGGGGTAGGTAAG

Downstream 100 bases:

>100_bases
ATCAAACGCCAGGGACGGTTCTCTTTGTTTGATTTTCAAACTTTCAAACAGAAAGAACCATTCCCTTTGTGTGGAAGTTT
GATATCCGCTATTCAAAGAA

Product: Zn-dependent protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MMSQKEIVNYTLEALNRAGAQKSQVNLTFTEKHEVNLEANEFTMVRTTFDTDIVLTAIKDKKKGTISINKSDIQSIDSAA
QDVILVAEASPEDEANDIAEYQPPKVFSSGDRTPDLEMMYYRMNELVKQIKEKYPKIILIQAFLYHEYKQSYFVNSNGVD
YVSNQGVYNFFAMFSSKDQDKTSSFNYTSFSLKNLDKELLNCGTLDILLKQLEEQTNTRPVEGKFVGDVIISPDAVNDIL
DFLTRSLSDNSIISGTSIYKDKLEKQIASPLLTVHSCPVSEEICSGYFVTKDGYEARNITIIDKGVLKNFLLSLYGSKKT
GLKYAYNDGGAFVIEPGETALDDMIRSVKKGILLMRFSGGYPSDSGDFSGVAKNSYLIEDGKIKYPISETMISGNIAEML
KNITAISKEQVNFGWQVLPWISVKGVTISGK

Sequences:

>Translated_431_residues
MMSQKEIVNYTLEALNRAGAQKSQVNLTFTEKHEVNLEANEFTMVRTTFDTDIVLTAIKDKKKGTISINKSDIQSIDSAA
QDVILVAEASPEDEANDIAEYQPPKVFSSGDRTPDLEMMYYRMNELVKQIKEKYPKIILIQAFLYHEYKQSYFVNSNGVD
YVSNQGVYNFFAMFSSKDQDKTSSFNYTSFSLKNLDKELLNCGTLDILLKQLEEQTNTRPVEGKFVGDVIISPDAVNDIL
DFLTRSLSDNSIISGTSIYKDKLEKQIASPLLTVHSCPVSEEICSGYFVTKDGYEARNITIIDKGVLKNFLLSLYGSKKT
GLKYAYNDGGAFVIEPGETALDDMIRSVKKGILLMRFSGGYPSDSGDFSGVAKNSYLIEDGKIKYPISETMISGNIAEML
KNITAISKEQVNFGWQVLPWISVKGVTISGK
>Mature_431_residues
MMSQKEIVNYTLEALNRAGAQKSQVNLTFTEKHEVNLEANEFTMVRTTFDTDIVLTAIKDKKKGTISINKSDIQSIDSAA
QDVILVAEASPEDEANDIAEYQPPKVFSSGDRTPDLEMMYYRMNELVKQIKEKYPKIILIQAFLYHEYKQSYFVNSNGVD
YVSNQGVYNFFAMFSSKDQDKTSSFNYTSFSLKNLDKELLNCGTLDILLKQLEEQTNTRPVEGKFVGDVIISPDAVNDIL
DFLTRSLSDNSIISGTSIYKDKLEKQIASPLLTVHSCPVSEEICSGYFVTKDGYEARNITIIDKGVLKNFLLSLYGSKKT
GLKYAYNDGGAFVIEPGETALDDMIRSVKKGILLMRFSGGYPSDSGDFSGVAKNSYLIEDGKIKYPISETMISGNIAEML
KNITAISKEQVNFGWQVLPWISVKGVTISGK

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1790682, Length=444, Percent_Identity=21.8468468468468, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 48134; Mature: 48134

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSQKEIVNYTLEALNRAGAQKSQVNLTFTEKHEVNLEANEFTMVRTTFDTDIVLTAIKD
CCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCCEEEEEEECCCCEEEEEECC
KKKGTISINKSDIQSIDSAAQDVILVAEASPEDEANDIAEYQPPKVFSSGDRTPDLEMMY
CCCCEEEECHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHH
YRMNELVKQIKEKYPKIILIQAFLYHEYKQSYFVNSNGVDYVSNQGVYNFFAMFSSKDQD
HHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHCCCCCC
KTSSFNYTSFSLKNLDKELLNCGTLDILLKQLEEQTNTRPVEGKFVGDVIISPDAVNDIL
CCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHH
DFLTRSLSDNSIISGTSIYKDKLEKQIASPLLTVHSCPVSEEICSGYFVTKDGYEARNIT
HHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHEEECCCCCHHHHCCEEEECCCCCCCEEE
IIDKGVLKNFLLSLYGSKKTGLKYAYNDGGAFVIEPGETALDDMIRSVKKGILLMRFSGG
EEEHHHHHHHHHHHHCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHCCEEEEEECCC
YPSDSGDFSGVAKNSYLIEDGKIKYPISETMISGNIAEMLKNITAISKEQVNFGWQVLPW
CCCCCCCCCCCCCCCEEEECCEEECCHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEECE
ISVKGVTISGK
EEEEEEEEECC
>Mature Secondary Structure
MMSQKEIVNYTLEALNRAGAQKSQVNLTFTEKHEVNLEANEFTMVRTTFDTDIVLTAIKD
CCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEEEECCCEEEEEEECCCCEEEEEECC
KKKGTISINKSDIQSIDSAAQDVILVAEASPEDEANDIAEYQPPKVFSSGDRTPDLEMMY
CCCCEEEECHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHH
YRMNELVKQIKEKYPKIILIQAFLYHEYKQSYFVNSNGVDYVSNQGVYNFFAMFSSKDQD
HHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHCCCCCC
KTSSFNYTSFSLKNLDKELLNCGTLDILLKQLEEQTNTRPVEGKFVGDVIISPDAVNDIL
CCCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEECCHHHHHHH
DFLTRSLSDNSIISGTSIYKDKLEKQIASPLLTVHSCPVSEEICSGYFVTKDGYEARNIT
HHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHEEECCCCCHHHHCCEEEECCCCCCCEEE
IIDKGVLKNFLLSLYGSKKTGLKYAYNDGGAFVIEPGETALDDMIRSVKKGILLMRFSGG
EEEHHHHHHHHHHHHCCCCCCCEEEEECCCEEEECCCCHHHHHHHHHHHCCEEEEEECCC
YPSDSGDFSGVAKNSYLIEDGKIKYPISETMISGNIAEMLKNITAISKEQVNFGWQVLPW
CCCCCCCCCCCCCCCEEEECCEEECCHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEECE
ISVKGVTISGK
EEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]